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Future Directions and Evolving Theories

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Assessing Headache Triggers

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Abstract

While understanding of headache triggers has progressed considerably, much remains to be elucidated. Several recent advances, such as scaling of triggers on a common metric, application of advanced statistical techniques, and utilization of biomarkers, show promise for improving measurement of triggers. This chapter introduces these emerging concepts and their potential for use in trigger assessment.

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References

  1. Brantley PJ, Waggoner CD, Jones GN, Rappaport NB. A daily stress inventory: development, reliability, and validity. J Behav Med. 1987;10:61–74.

    Article  CAS  Google Scholar 

  2. Borkum JM. Migraine triggers and oxidative stress: a narrative review and synthesis. Headache. 2016;56:12–35.

    Article  Google Scholar 

  3. Borkum JM. The migraine attack as a homeostatic, neuroprotective response to brain oxidative stress: preliminary evidence for a theory. Headache. 2018;58:118–35.

    Article  Google Scholar 

  4. Turner DP, Lebowitz AD, Chtay I, Houle TT. Headache triggers as surprise. Headache. 2019;59:495–508.

    Article  Google Scholar 

  5. Shannon CE. A mathematical theory of communication. Bell Syst Tech J. 1948;27:379–423.

    Article  Google Scholar 

  6. Rényi A. On measures of entropy and information. In: Proceedings of the fourth Berkeley symposium in mathematical statistics. Berkeley: University of California Press; 1961.

    Google Scholar 

  7. Barto A, Mirolli M, Baldassarre G. Novelty or surprise? Front Psych. 2013;4:907. https://doi.org/10.3389/fpsyg.2013.00907.

    Article  Google Scholar 

  8. Ince RA. Measuring multivariate redundant information with pointwise common change in surprisal. Entropy. 2017;19:318. https://doi.org/10.3390/e19070318.

    Article  CAS  Google Scholar 

  9. Itti L, Baldi P. Bayesian surprise attracts human attention. Vis Res. 2009;49:1295–306.

    Article  Google Scholar 

  10. McDaniel RR Jr, Jordan ME, Fleeman BF. Surprise, surprise, surprise! A complexity science view of the unexpected. Health Care Manag Rev. 2003;28:266–78.

    Article  Google Scholar 

  11. Ho TW, Edvinsson L, Goadsby PJ. CGRP and its receptors provide new insights into migraine pathophysiology. Nat Rev Neurol. 2010;6:573–82.

    Article  CAS  Google Scholar 

  12. Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97:553–622.

    Article  Google Scholar 

  13. Goadsby PJ, Holland PR. An update: pathophysiology of migraine. Neurol Clin. 2019;37:651–71.

    Article  Google Scholar 

  14. Puledda F, Messina R, Goadsby PJ. An update on migraine: current understanding and future directions. J Neurol. 2017;264:2031–9.

    Article  CAS  Google Scholar 

  15. Houle TT, Turner DP, Golding AN, Porter JAH, Martin VT, Penzien DB, Tegeler CH. Forecasting individual headache attacks using perceived stress: development of a multivariable prediction model for persons with episodic migraine. Headache. 2017;57:1041–50.

    Article  Google Scholar 

  16. Lipton RB, Pavlovic JM, Buse DC. Why migraine forecasting matters. Headache. 2017;57:1023–5.

    Article  Google Scholar 

  17. Turner DP, Lebowitz AD, Chtay I, Houle TT. Forecasting migraine attacks and the utility of identifying triggers. Curr Pain Headache Rep. 2018;22:62. https://doi.org/10.1007/s11916-018-0715-3.

    Article  PubMed  Google Scholar 

  18. Turner DP, Leffert LR, Houle TT. The treatment implications of forecasting headache. Pain Manag. 2020;10:349–52.

    Article  Google Scholar 

  19. Turner DP, Smitherman TA, Martin VT, et al. Causality and headache triggers. Headache. 2013;53:628–35.

    Article  Google Scholar 

  20. Houle TT, Turner DP. Natural experimentation is a challenging method for identifying headache triggers. Headache. 2013;53:636–43.

    Article  Google Scholar 

  21. Pearl J. Causality: models, reasoning and inference. 2nd ed. New York: Cambridge University Press; 2009.

    Book  Google Scholar 

  22. Pearl J, Glymour M, Jewell NP. Causal inference in statistics: a primer. West Sussex: John Wiley & Sons; 2016.

    Google Scholar 

  23. Pearl J, Mackenzie D. The book of why: the new science of cause and effect. New York: Basic Books; 2018.

    Google Scholar 

  24. Durham P, Papapetropoulos S. Biomarkers associated with migraine and their potential role in migraine management. Headache. 2013;53:1262–77.

    Article  Google Scholar 

  25. Lambert GA, Zagami AS. The mode of action of migraine triggers: a hypothesis. Headache. 2009;49:253–75.

    Article  Google Scholar 

  26. Loder E, Rizzoli P. Biomarkers in migraine: their promise, problems, and practical applications. Headache. 2006;46:1046–58.

    Article  Google Scholar 

  27. Holsteen KK, Hittle M, Barad M, Nelson LM. Development and internal validation of a multivariable prediction model for individual episodic migraine attacks based on daily trigger exposures. Headache. 2020;60:2364–79.

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Dana P. Turner

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  1. Dana P. Turner
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Correspondence to Dana P. Turner .

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Turner, D.P. (2021). Future Directions and Evolving Theories. In: Assessing Headache Triggers . Springer, Cham. https://doi.org/10.1007/978-3-030-81949-1_9

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  • DOI: https://doi.org/10.1007/978-3-030-81949-1_9

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-81948-4

  • Online ISBN: 978-3-030-81949-1

  • eBook Packages: MedicineMedicine (R0)

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