Abstract
The first FDA-cleared platelet-rich plasma (PRP) collection devices were developed for use in orthopedic surgery in the 1990s, but recently there has been an explosion in off-label use of newer devices for aesthetic indications. The protocol for PRP preparation involves blood collection, platelet isolation via centrifugation, platelet activation, and administration into target tissues. Each of these steps introduces a source of variation that affects the composition and efficacy of the final PRP product, and this explains the significant heterogeneity seen among the preparation systems currently on the market. A number of classification systems have been proposed to help systematize the reporting of PRP outcomes, but they can also be used to compare devices. Aesthetic clinicians must understand the components of a PRP preparation system in order to critically evaluate the scientific literature on this topic and to offer the most effective treatment regimen to patients. The nuances pertaining to each of the preparatory factors discussed in this chapter are sources of great debate and require further study.
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Krueger, S., Ibrahim, O. (2021). Preparation Systems. In: Khetarpal, S. (eds) Aesthetic Clinician's Guide to Platelet Rich Plasma. Springer, Cham. https://doi.org/10.1007/978-3-030-81427-4_3
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DOI: https://doi.org/10.1007/978-3-030-81427-4_3
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