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Neuroprotection in Subarachnoid Hemorrhage

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Management of Subarachnoid Hemorrhage

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Abstract

All cases of subarachnoid hemorrhage, in the absence of treatment, can eventually cause secondary brain injury. Metabolic or biochemical events lead to neuroinflammation and death of nerve cells. Neuroprotection includes all interventions that prevent or mitigate secondary brain injury. Despite advancements in neuroscience, the evidence supporting the currently used neuroprotective strategies is still lacking. Many proposed strategies have conflicting evidence; some show benefit in experimental trials (mainly animal) but not in human studies. Many of these strategies have nevertheless been supported by guidelines from neurocritical care societies. These strategies can be classified into general measures and pharmacologic measures.

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Author information

Authors and Affiliations

  1. Department of Anesthesia, Perioperative Medicine and Critical Care, Hamad Medical Corporation, Doha, Qatar

    Arunabha Karmakar & Yasir M. Abdelwahid

  2. Department of Trauma Intensive Care Unit, Hamad Medical Corporation, Doha, Qatar

    Gustav Strandvik

  3. Weill Cornell Medical School, Ar-Rayyan, Qatar

    Gustav Strandvik

  4. College of Medicine at Qatar University, Doha, Qatar

    Gustav Strandvik

Authors
  1. Arunabha Karmakar
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  2. Yasir M. Abdelwahid
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  3. Gustav Strandvik
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Corresponding author

Correspondence to Gustav Strandvik .

Editor information

Editors and Affiliations

  1. Anesthesia, Perioperative Medicine and Critical Care Department, Hamad General Hospital Hamad Medical Corporation, Doha, Qatar

    Adel E. Ahmed Ganaw

  2. Department of Anesthesia Perioperative Medicine and Critical Care, Surgical Intensive Care Unit Hamad Medical Corporation, Doha, Qatar

    Nissar Shaikh

  3. Faculty of Medicine, Tanta University, Tanta, Egypt

    Nabil A. Shallik

  4. Department of Anesthesiology, University of Muenster, Muenster, Germany

    Marco Abraham E. Marcus

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Karmakar, A., Abdelwahid, Y.M., Strandvik, G. (2022). Neuroprotection in Subarachnoid Hemorrhage. In: Ganaw, A.E.A., Shaikh, N., Shallik, N.A., Marcus, M.A.E. (eds) Management of Subarachnoid Hemorrhage. Springer, Cham. https://doi.org/10.1007/978-3-030-81333-8_4

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  • DOI: https://doi.org/10.1007/978-3-030-81333-8_4

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