Skip to main content

Upper Tibial Osteotomy or Unicompartmental Knee Arthroplasty for Medial Compartment Knee Osteoarthritis: Evidence-Based Indications for Treatment

  • Chapter
  • First Online:
Controversies in Orthopaedic Surgery of the Lower Limb

Abstract

Available treatments for medial compartment osteoarthritis (OA) of the knee can include non-surgical and surgical options. Currently accepted surgical treatments aim to either preserve the joint surfaces whilst addressing malalignment of the limb (osteotomy) or replace the joint itself (arthroplasty). Where total knee arthroplasty (TKA) has historically been a popular choice in these patients, unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) have evolved to provide favourable outcomes in selected patients. There has been much debate as to which procedure is preferable in these circumstances, suggesting a significant overlap in reported indications. In this chapter we describe the historical origins of both HTO and UKA, exploring how changing indications reflect improvements in surgical techniques combined with a better understanding of the natural history of OA. HTO and UKA both provide excellent results in the treatment of medial compartment knee OA. Patients who experience reliably good outcomes in either group are clinically and radiographically distinct from each other. It is therefore likely that the group of patients in whom HTO and UKA are equally indicated is much smaller than has been previously suggested.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Morgan OJ, Hillstrom HJ, Ellis SJ, Golightly YM, Russell R, Hannan MT, et al. Osteoarthritis in England: incidence trends from National Health Service Hospital Episode Statistics. ACR Open Rheumatol. 2019;1:493–8.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. Chen A, Gupte C, Akhtar K, Smith P, Cobb J. The global economic cost of osteoarthritis: how the UK compares. Arthritis. 2012;2012:698709. https://doi.org/10.1155/2012/698709.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Brittain R, Dawson-Bowling S, Goldberg A, Toms A, Young E, Mccormack V, et al. NJR 17th Annual Report. 2020.

    Google Scholar 

  4. Ledingham J, Regan M, Jones A, Doherty M. Radiographic patterns and associations of osteoarthritis of the knee in patients referred to hospital. Ann Rheum Dis. 1993;52:520–6.

    CAS  PubMed  PubMed Central  Google Scholar 

  5. Wise BL, Niu J, Yang M, Lane NA, Harvey W, Felson DT, et al. Patterns of compartment involvement in tibiofemoral osteoarthritis in men and women and in whites and African Americans. Arthritis Care Res. 2012;64:847–52.

    Google Scholar 

  6. London NJ, Miller LE, Block JE. Clinical and economic consequences of the treatment gap in knee osteoarthritis management. Med Hypotheses. 2011;76:887–92.

    PubMed  Google Scholar 

  7. Jones L, Knezevic K, Beard D, Price A. The failing medial compartment of the knee: pain profile as severe as those requiring arthroplasty. Osteoarthr Cartil. 2012. https://doi.org/10.1016/j.joca.2012.02.436.

  8. Ahlbäck S. Osteoarthrosis of the knee. A radiographic investigation. Acta Radiol Diagn (Stockh). 1968;Suppl 277:7–72.

    Google Scholar 

  9. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis. 1957;16:494–502.

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Luyten FP, Denti M, Filardo G, Kon E, Engebretsen L. Definition and classification of early osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc. 2012;20:401–6.

    PubMed  Google Scholar 

  11. Sharma L, Song J, Felson DT, Cahue S, Shamiyeh E, Dunlop DD. The role of knee alignment in disease progression and functional decline in knee osteoarthritis. J Am Med Assoc. 2001;286:188–95.

    CAS  Google Scholar 

  12. Palmer JS, Jones LD, Monk AP, Nevitt M, Lynch J, Beard DJ, et al. Varus alignment of the proximal tibia is associated with structural progression in early to moderate varus osteoarthritis of the knee. Knee Surg Sports Traumatol Arthrosc. 2020;28:3279–86.

    PubMed  PubMed Central  Google Scholar 

  13. Babis GC, An KN, Chao EYS, Rand JA, Sim FH. Double level osteotomy of the knee: a method to retain joint-line obliquity clinical results. J Bone Joint Surg. 2002;84-A:1380–8.

    Google Scholar 

  14. Jackson JP, Waugh W. Tibial osteotomy for osteoarthritis of the knee. J Bone Joint Surg. 1961;43-B:746–51.

    CAS  Google Scholar 

  15. Gariépy R. High tibial valgus osteotomy. The lateral approach for genu varum. Oper Orthop Traumatol. 1996. https://doi.org/10.1007/BF02510282.

  16. Coventry MB, Ilstrup DM, Wallrichs SL. Proximal tibial osteotomy: a critical long-term study of eighty-seven cases. J Bone Joint Surg. 1993;75-A:196–201.

    Google Scholar 

  17. Lobenhoffer P, Agneskirchner JD. Improvements in surgical technique of valgus high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc. 2003;11:132–8.

    PubMed  Google Scholar 

  18. Paley D, Paley D. Normal lower limb alignment and joint orientation. In: Princ. Deform. Correct. 2002. p. 1–18.

    Google Scholar 

  19. Fujisawa Y, Masuhara K, Shiomi S. The effect of high tibial osteotomy on osteoarthritis of the knee. An arthroscopic study of 54 knee joints. Orthop Clin North Am. 1979;10:585–608.

    CAS  PubMed  Google Scholar 

  20. Martay JL, Palmer AJ, Bangerter NK, Clare S, Monk AP, Brown CP, et al. A preliminary modeling investigation into the safe correction zone for high tibial osteotomy. Knee. 2018;25:286–95.

    PubMed  Google Scholar 

  21. UKKOR research collaboration. The United Kingdom Knee Osteotomy Registry: The First Annual Report 2018.

    Google Scholar 

  22. Brinkman JM, Lobenhoffer P, Agneskirchner JD, Staubli AE, Wymenga AB, Van Heerwaarden RJ. Osteotomies around the knee: patient selection, stability of fixation and bone healing in high tibial osteotomies. J Bone Joint Surg. 2008;90-B:1548–57.

    Google Scholar 

  23. Duivenvoorden T, Brouwer RW, Baan A, Bos PK, Reijman M, Bierma-Zeinstra SMA, et al. Comparison of closing-wedge and opening-wedge high tibial osteotomy for medial compartment osteoarthritis of the knee: a randomized controlled trial with a six-year follow-up. J Bone Joint Surg. 2014;96-A:1425–32.

    Google Scholar 

  24. Koh IJ, Kim MS, Sohn S, Song KY, Choi NY, Jung H, et al. Predictive factors for satisfaction after contemporary unicompartmental knee arthroplasty and high tibial osteotomy in isolated medial femorotibial osteoarthritis. Orthop Traumatol Surg Res. 2019;105:77–83.

    PubMed  Google Scholar 

  25. Floerkemeier S, Staubli AE, Schroeter S, Goldhahn S, Lobenhoffer P. Outcome after high tibial open-wedge osteotomy: a retrospective evaluation of 533 patients. Knee Surg Sports Traumatol Arthrosc. 2013;21:170–80.

    PubMed  Google Scholar 

  26. Campbell W. Interposition of vitallium plates in arthroplasties of the knee: preliminary report. Am J Surg. 1940;47:639–41.

    Google Scholar 

  27. McKeever D. Tibial plateau prosthesis. Clin Orthop Relat Res. 1960;18:86–95.

    Google Scholar 

  28. MacIntosh DL. Hemiarthroplasty of the knee using a space occupying prosthesis for painful varus and valgus deformities. J Bone Joint Surg. 1958;40-A:1431.

    Google Scholar 

  29. Insall J, Aglietti P. A five to seven-year follow-up of unicondylar arthroplasty. J Bone Joint Surg. 1980;62-A:1329–37.

    Google Scholar 

  30. Laskin RS. Unicompartmental tibiofemoral resurfacing arthroplasty. J Bone Joint Surg. 1978;60-A:182–5.

    Google Scholar 

  31. Kozinn SC, Scott R. Unicondylar knee arthroplasty. J Bone Joint Surg. 1989;71-A:145–50.

    Google Scholar 

  32. Stern SH, Becker MW, Insall JN. Unicondylar knee arthroplasty: an evaluation of selection criteria. Clin Orthop Relat Res. 1993;286:143–8.

    Google Scholar 

  33. Goodfellow J. Unicompartmental arthroplasty with the Oxford knee. Oxford; 2011.

    Google Scholar 

  34. Pandit H, Hamilton TW, Jenkins C, Mellon SJ, Dodd CAF, Murray DW. The clinical outcome of minimally invasive Phase 3 Oxford unicompartmental knee arthroplasty. Bone Joint J. 2015;97-B:1493–500.

    CAS  PubMed  Google Scholar 

  35. Hamilton TW, Pandit HG, Inabathula A, Ostlere SJ, Jenkins C, Mellon SJ, et al. Unsatisfactory outcomes following unicompartmental knee arthroplasty in patients with partial thickness cartilage loss. Bone Joint J. 2017;99-B:475–82.

    CAS  PubMed  Google Scholar 

  36. Pandit H, Gulati A, Jenkins C, Barker K, Price AJ, Dodd CAF, et al. Unicompartmental knee replacement for patients with partial thickness cartilage loss in the affected compartment. Knee. 2011;18:168–71.

    CAS  PubMed  Google Scholar 

  37. Niinimäki TT, Murray DW, Partanen J, Pajala A, Leppilahti JI. Unicompartmental knee arthroplasties implanted for osteoarthritis with partial loss of joint space have high re-operation rates. Knee. 2011;18:432–5.

    PubMed  Google Scholar 

  38. Cao ZW, Mai XJ, Wang J, Feng EH, Huang YM. Unicompartmental knee arthroplasty versus high tibial osteotomy for knee osteoarthritis: a systematic review and meta-analysis. J Arthroplast. 2018;33:952–9.

    Google Scholar 

  39. Börjesson M, Weidenhielm L, Mattsson E, Olsson E. Gait and clinical measurements in patients with knee osteoarthritis after surgery: a prospective 5-year follow-up study. Knee. 2005;12:121–7.

    PubMed  Google Scholar 

  40. Stukenborg-Colsman C, Wirth CJ, Lazovic D, Wefer A. High tibial osteotomy versus unicompartmental joint replacement in unicompartmental knee joint osteoarthritis: 7-10-Year follow-up prospective randomised study. Knee. 2001;8:187–94.

    CAS  PubMed  Google Scholar 

  41. Dettoni F, Bonasia DE, Castoldi F, Bruzzone M, Blonna D, Rossi R. High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment arthrosis of the knee: a review of the literature. Iowa Orthop J. 2010;30:131–40.

    PubMed  PubMed Central  Google Scholar 

  42. Belsey J, Yasen SK, Jobson S, Faulkner J, Wilson AJ. Return to physical activity after high tibial osteotomy or unicompartmental knee arthroplasty: a systematic review and pooling data analysis. Am J Sports Med. 2021;49(5):1372–80. https://doi.org/10.1177/0363546520948861.

    Article  PubMed  Google Scholar 

  43. Beard DJ, Davies LJ, Cook JA, McLennan G, Price A, Kent S, et al. The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial. Lancet. 2019;394:746–56.

    PubMed  PubMed Central  Google Scholar 

  44. Pannell WC, Heidari KS, Mayer EN, Zimmerman K, Heckmann N, McKnight B, et al. High tibial osteotomy survivorship: a population-based study. Orthop J Sport Med. 2019;7:1–7.

    Google Scholar 

  45. O’Rourke MR, Gardner JJ, Callaghan JJ, Liu SS, Goetz DD, Vittetoe DA, et al. The John Insall Award: unicompartmental knee replacement. Clin Orthop Relat Res. 2005;440:27–37.

    PubMed  Google Scholar 

  46. Vorlat P, Putzeys G, Cottenie D, Van Isacker T, Pouliart N, Handelberg F, et al. The Oxford unicompartmental knee prosthesis: an independent 10-year survival analysis. Knee Surg Sports Traumatol Arthrosc. 2006;14:40–5.

    PubMed  Google Scholar 

  47. Kumar A, Fiddian NJ. Medial unicompartmental arthroplasty of the knee. Knee. 1999;6:21–3.

    Google Scholar 

  48. Kristensen PW, Holm HA, Varnum C. Up to 10-year follow-up of the Oxford medial partial knee arthroplasty—695 cases from a single institution. J Arthroplast. 2013;28:195–8.

    Google Scholar 

  49. Robertsson O, W-Dahl A. The risk of revision after TKA is affected by previous HTO or UKA. Clin Orthop Relat Res. 2015;473:90–3.

    PubMed  Google Scholar 

  50. Spahn G, Hofmann GO, von Engelhardt LV, Li M, Neubauer H, Klinger HM. The impact of a high tibial valgus osteotomy and unicondylar medial arthroplasty on the treatment for knee osteoarthritis: a meta-analysis. Knee Surg Sports Traumatol Arthrosc. 2013;21:96–112.

    PubMed  Google Scholar 

  51. Sokol DK. Update on the UK law on consent. BMJ. 2015;350:h1481.

    PubMed  Google Scholar 

  52. Sanderson J, Kay N, Watts R. Universal Personalised Care. NHS Engl. 2019.

    Google Scholar 

  53. Skou ST, Roos EM, Laursen MB, Rathleff MS, Arendt-Nielsen L, et al. A randomized, controlled trial of total knee replacement. N Engl J Med. 2015;373:1597–606.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Shearman, A.D., Bottomley, N.J., Jackson, W.F.M., Price, A.J. (2021). Upper Tibial Osteotomy or Unicompartmental Knee Arthroplasty for Medial Compartment Knee Osteoarthritis: Evidence-Based Indications for Treatment. In: Rodríguez-Merchán, E.C., Liddle, A.D. (eds) Controversies in Orthopaedic Surgery of the Lower Limb. Springer, Cham. https://doi.org/10.1007/978-3-030-80695-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-80695-8_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-80694-1

  • Online ISBN: 978-3-030-80695-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics