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Guidelines and Evidence-Based Recommendations for the Radiosurgical Treatment of CNS Meningiomas

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Stereotactic Radiosurgery for the Treatment of Central Nervous System Meningiomas

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Abstract

Since the 1990s, the introduction of SRS has radically modified standard medical practice for the treatment of several central nervous system (CNS) and intracranial pathologies, particularly meningiomas (MNs). In the last decade, there have been important changes in the management of MNs due to the publication and diffusion of a large number of guidelines (GLs) for their diagnosis and treatment. In this chapter, the authors summarize the highlights from the main GLs recently published. The aim is to provide the reader with clear and precise recommendation on when and how to perform SRS for CNS MNs.

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Abbreviations

CISS:

Constructive interference in steady state

CNS:

Central nervous system

CT:

Computed tomography

EANO:

European Association of Neuro-Oncology

GI:

WHO Grade I MN

GII:

WHO Grade II MN

GIII:

WHO Grade III MN

GLs:

Guidelines

GTR:

Gross total resection

Gy:

Gray

ISRS:

International Stereotactic Radiosurgery Society

LGK-RS:

Leksell Gamma Knife radiosurgery

LINAC:

Linear accelerator

LTC:

Local tumour control

MDT:

Multidisciplinary team

MNs:

Meningiomas

MRI:

Magnetic resonance imaging

NHS:

National Health System

PD:

Prescription dose

PFS:

Progression-free survival

PMCC:

Princess Margaret Cancer Centre

RT:

Radiotherapy

SRS:

Stereotactic radiosurgery

SRT:

Stereotactic radiotherapy

STR:

Subtotal resection

WHO:

World Health Organization

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Author information

Authors and Affiliations

  1. Unità di Gamma Knife, UOC di Neurochirurgia, Istituto Ospedaliero Poliambulanza, Brescia, Italy

    Alberto Franzin, Cesare Giorgi & Lodoviga Giudice

  2. Neurosurgery Unit, Neuroscience Department, Carlo Poma Hospital, Mantova, Italy

    Bruno Zanotti

  3. Neurology Service, Anemos Neuroscience, Reggio Emilia, Italy

    Angela Verlicchi

  4. USO Radiochirurgia e Neurochirurgia Stereotassica, UOC Neurochirurgia B, Dipartimento ad Attività Integrata (DAI) di Neuroscienze, Azienda Ospedaliera Universitaria Integrta (AOUI), Verona, Italy

    Antonio Nicolato

Authors
  1. Alberto Franzin
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  2. Bruno Zanotti
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  3. Cesare Giorgi
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  4. Lodoviga Giudice
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  5. Angela Verlicchi
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  6. Antonio Nicolato
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Corresponding author

Correspondence to Antonio Nicolato .

Editor information

Editors and Affiliations

  1. Department of Neuroscience, Radiosurgery and Stereotactic Neurosurgery Section – Neurosurgery B Unit, University Hospital, Verona, Italy

    Michele Longhi

  2. Department of Neurological Sciences, Neurosurgery, University of Milan GVM Care & Research – Maria Cecilia Hospital, Cotignola, Italy

    Enrico D. F. Motti

  3. Department of Neuroscience, Radiosurgery and Stereotactic Neurosurgery Section – Neurosurgery B Unit, University Hospital, Verona, Italy

    Antonio Nicolato

  4. Director of Functional Neurosurgery & Gamma Knife Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy

    Piero Picozzi

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Franzin, A., Zanotti, B., Giorgi, C., Giudice, L., Verlicchi, A., Nicolato, A. (2021). Guidelines and Evidence-Based Recommendations for the Radiosurgical Treatment of CNS Meningiomas. In: Longhi, M., Motti, E.D.F., Nicolato, A., Picozzi, P. (eds) Stereotactic Radiosurgery for the Treatment of Central Nervous System Meningiomas. Springer, Cham. https://doi.org/10.1007/978-3-030-79419-4_17

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