Abstract
For a long time, the adipose tissue’s medical use was restricted to elementary purposes including volume reduction and volume augmentation. However, in the last decades more noble purposes emerged, above all adipose tissue’s regenerative abilities, which depend on a small cellular population called stromal vascular fraction (SVF) including mesenchymal cells. While in the past, extreme attention was paid to avoid the breakdown of weaker mature adipocytes, nowadays the use of more important mechanical forces is allowed to harvest and process the adipose tissue, because SVF is more resistant. During harvesting, it is possible to use microcannulas with a diameter less than 1 mm, and during processing, it is possible to use transfer and nanotransfer to decrease the fat cluster size. Moreover, mechanical forces destroy a large number of mature adipocytes to obtain increased SVF yield and regenerative potential.
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Trivisonno, A. (2022). Stem Cell Research, Concepts, and Emerging Technologies. In: Kalaaji, A. (eds) Plastic and Aesthetic Regenerative Surgery and Fat Grafting. Springer, Cham. https://doi.org/10.1007/978-3-030-77455-4_10
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DOI: https://doi.org/10.1007/978-3-030-77455-4_10
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