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The Role of Chromatographic and Electromigration Techniques in Foodomics

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Separation Techniques Applied to Omics Sciences

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1336))

Abstract

Foodomics is the discipline aimed at studying the prevention of diseases by food, identifying chemical, biological and biochemical food contaminants, determining changes in genetically modified foods, identifying biomarkers able to confirm the authenticity and quality of foods or studying the safety, quality and traceability of foods, among other issues. It is mainly based on the use of genomic, transcriptomic, proteomic and metabolomic tools, among others, in order to understand the effect of food on animals and humans at the level of genes, messenger ribonucleic acid, proteins and metabolites. Since the first definition of Foodomics, a reasonable number of works have shown the extremely high possibilities of this discipline, which is highly based on the use of advanced analytical hyphenated techniques – especially for proteomics and metabolomics. This book chapter aims at providing a general description of the role of chromatographic and electromigration techniques that are currently being applied to achieve the main objectives of Foodomics, particularly in the proteomic and metabolomic fields, since most published works have been focused on these approaches, and to highlight relevant applications.

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Abbreviations

2D:

Two-dimensional

ACN:

Acetonitrile

C18:

Octadecylsilane

CE:

Capillary electrophoresis

CSIC:

National Research Council of Spain

DAD:

Diode array detector

ddPCR:

Droplet digital polymerase chain reaction

DNA:

Deoxyribonucleic acid

EOF:

Electroosmotic flow

ESI:

Electrospray ionization

FT:

Fourier transform

GC:

Gas chromatography

HILIC:

Hydrophilic interaction liquid chromatography

HPLC:

High-performance liquid chromatography

HRM:

High-resolution melting

HS-SPME:

Headspace solid-phase microextraction

ICR:

Ion cyclotron resonance

IT:

Ion trap

LAMP:

Loop-mediated isothermal amplification

LC:

Liquid chromatography

LCxLC:

Two-dimensional liquid chromatography

m/z:

Mass/charge ratio

MALDI:

Matrix-assisted laser desorption ionization

miRNA:

Micro-ribonucleic acid

mRNA:

Messenger ribonucleic acid

MS:

Mass spectrometry

MS/MS:

Tandem mass spectrometry

NMR:

Nuclear magnetic resonance

PAGE:

Polyacrylamide gel electrophoresis

PCR:

Polymerase chain reaction

PTM:

Posttranslational modification

Q:

Quadrupole

QqQ:

Triple quadrupole

RNA:

Ribonucleic acid

rRNA:

Ribosomal ribonucleic acid

SDS:

Sodium dodecyl sulphate

TOF:

Time-of-flight

tRNA:

Transfer ribonucleic acid

UHPLC:

Ultra high-performance liquid chromatography

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Acknowledgements

J.G.S. would like to thank “Cabildo de Tenerife” for the Agustín de Betancourt contract at the Universidad de La Laguna.

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Authors and Affiliations

  1. Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Spain

    Javier González-Sálamo, Diana Angélica Varela-Martínez & Javier Hernández-Borges

  2. Departamento de Ciencias Básicas, Facultad de Ingeniería, Universidad EAN, Bogotá D.C., Colombia

    Diana Angélica Varela-Martínez & Miguel Ángel González-Curbelo

  3. Instituto Universitario de Enfermedades Tropicales y Salud Pública, Universidad de La Laguna (ULL), San Cristóbal de La Laguna, Spain

    Javier Hernández-Borges

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  1. Javier González-Sálamo
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Correspondence to Javier Hernández-Borges .

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  1. Analytical Chemistry Department, University of Campinas, Institute of Chemistry, Campinas, São Paulo, Brazil

    Ana Valéria Colnaghi Simionato

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González-Sálamo, J., Varela-Martínez, D.A., González-Curbelo, M.Á., Hernández-Borges, J. (2021). The Role of Chromatographic and Electromigration Techniques in Foodomics. In: Colnaghi Simionato, A.V. (eds) Separation Techniques Applied to Omics Sciences. Advances in Experimental Medicine and Biology(), vol 1336. Springer, Cham. https://doi.org/10.1007/978-3-030-77252-9_3

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