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Quality of Life in Neuromuscular Disorders

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Pulmonary Function Measurement in Noninvasive Ventilatory Support

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Abstract

Neuromuscular disorders (NMDs) are a heterogeneous group of diseases causing progressive muscular impairment, which can even evolve into respiratory failure. Mechanical ventilation, mostly noninvasive ventilation (NIV), can often be necessary. In this chapter we will review the role of NIV in NMDs and how it could contribute to improve survival and quality of life (QoL), especially when timely employed.

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Abbreviations

AHI:

Apnea/hypopnea index

ALS:

Amyotrophic lateral sclerosis

BiPAP:

Bilevel positive airway pressure

cmH2O:

Centimeters of water

CO2:

Carbon dioxide

DMD:

Duchenne muscular dystrophy

FVC:

Forced vital capacity

HRQOL:

Health-related quality of life

INQoL:

Individualized Neuromuscular Quality of Life Questionnaire

iVAPS:

Intelligent volume-assured pressure support

MEP:

Maximum expiratory pressure

MIP:

Maximal inspiratory pressure

NIV:

Noninvasive ventilation

NMDs:

Neuromuscular disorders

O2:

Oxygen

pCO2:

Carbon dioxide partial pressure

Ppl:

Pleural pressure

PSG:

Polysomnography

QoL:

Quality of life

SMA:

Spinal muscle atrophy—congenital myopathy

SNIP:

Sniff nasal inspiratory pressure

SpO2:

Pulsatile oxygen saturation

VC:

Vital capacity

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Author information

Authors and Affiliations

  1. Department of Anesthesia and Intensive Care, University of Foggia, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Foggia, Italy

    Gilda Cinnella, Guido Gambetti & Michela Rauseo

Authors
  1. Gilda Cinnella
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  2. Guido Gambetti
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  3. Michela Rauseo
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Corresponding author

Correspondence to Michela Rauseo .

Editor information

Editors and Affiliations

  1. Intensive Care Unit, Hospital General Universitario Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

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Cinnella, G., Gambetti, G., Rauseo, M. (2021). Quality of Life in Neuromuscular Disorders. In: Esquinas, A.M. (eds) Pulmonary Function Measurement in Noninvasive Ventilatory Support. Springer, Cham. https://doi.org/10.1007/978-3-030-76197-4_44

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  • DOI: https://doi.org/10.1007/978-3-030-76197-4_44

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-76196-7

  • Online ISBN: 978-3-030-76197-4

  • eBook Packages: MedicineMedicine (R0)

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