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Chronic Neuromuscular Disorders

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Pulmonary Function Measurement in Noninvasive Ventilatory Support

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Abstract

Spirometry, respiratory muscles pressures, peak cough flow, and arterial (or capillary) blood gases are the most commonly used pulmonary function tests for the assessment of patients with neuromuscular disorders. These tests can be used for disease monitoring and patient prognostication, as well as for decision-making regarding the initiation of ventilatory support. However, the use of daytime pulmonary function tests as screening tools for the prediction of sleep hypoventilation cannot be recommended in patients with neuromuscular disorders.

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Abbreviations

ALS:

Amyotrophic lateral sclerosis

BE:

Base excess

BG:

Blood gases

DMD:

Duchenne muscular dystrophy

FRC:

Functional residual capacity

FVC:

Forced vital capacity

IVC:

Inspiratory vital capacity

NIV:

Noninvasive ventilation

NMDs:

Neuromuscular disorders

PCF:

Peak cough flow

PEmax:

Maximum static expiratory pressure

PImax:

Maximum static inspiratory pressure

REM:

Rapid eye movement

SDB:

Sleep-disordered breathing

SNIP:

Sniff nasal inspiratory pressure

SVC:

Slow vital capacity

tcPCO2:

Transcutaneous PCO2

TLC:

Total lung capacity

twPdi:

Twitch transdiaphragmatic pressure

VC:

Vital capacity

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Author information

Authors and Affiliations

  1. Department of Respiratory Failure, “Georgios Papanikolaou” General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Exohi, Greece

    Michalis Agrafiotis & Athanasia Pataka

  2. Department of Pulmonary Medicine, “Georgios Papanikolaou” General Hospital of Thessaloniki, Exohi, Greece

    Stavros Tryfon & Afroditi Boutou

Authors
  1. Michalis Agrafiotis
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  2. Stavros Tryfon
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  3. Afroditi Boutou
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  4. Athanasia Pataka
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Editor information

Editors and Affiliations

  1. Intensive Care Unit, Hospital General Universitario Morales Meseguer, Murcia, Spain

    Antonio M. Esquinas

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Agrafiotis, M., Tryfon, S., Boutou, A., Pataka, A. (2021). Chronic Neuromuscular Disorders. In: Esquinas, A.M. (eds) Pulmonary Function Measurement in Noninvasive Ventilatory Support. Springer, Cham. https://doi.org/10.1007/978-3-030-76197-4_13

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  • DOI: https://doi.org/10.1007/978-3-030-76197-4_13

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-76196-7

  • Online ISBN: 978-3-030-76197-4

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