Abstract
Twenty years ago, City of Hope (COH), a National Cancer Institute-designated Comprehensive Cancer Center located in the city of Duarte, California, recognized the need to bridge the gap between basic discovery research and clinical translation for its own academic researchers and their collaborators. To that end, COH constructed three good manufacturing practices (GMP) compliant facilities over the course of two decades: the Center for Biomedicine and Genetics (CBG), the Cellular Therapy Production Center, and the Chemical GMP Synthesis Facility. The ultimate aim of these facilities is to produce and test emerging therapeutic innovations in a clinical setting while ensuring patient safety. Here, we focus on the CBG due to its broad experience with different types of biologic products.
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Couture, L., Hsu, D., Shad, Y., Vashi, M., Nallu, R., Gold, J. (2022). Design and Operation of a Multiuse GMP Facility at the City of Hope. In: Gee, A.P. (eds) Cell Therapy. Springer, Cham. https://doi.org/10.1007/978-3-030-75537-9_16
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DOI: https://doi.org/10.1007/978-3-030-75537-9_16
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