We dream of a self-sustaining ‘Home of the Future’ that will be a home and a workplace for two persons. This home should be utilising digital technologies to optimise its resource consumption as well as vital resource production. We envisage of a home capable of producing energy, water and food and an open office that will be a hosting bed for start-ups and entrepreneurs to test and monitor their daring ideas and solutions in real-life. The objective of this book is to investigate the self-sustaining concept under the water-energy-food nexus perspective. To apply the theory into practice, we will design a self-sustaining house that will serve as an Open Digital Innovation Hub (ODIH) for entrepreneurs, start-ups and researchers. ODIH, as a platform, will serve like a catalyst for exploring the boundaries of Internet of Things, Artificial Intelligence, Smart Charging and Blockchain that can be used in resource management.