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Solidago virgaurea L.—Chemical Composition, Traditional and Medicinal Use, Pharmaceutical Properties, Potential Applications, and Biotechnological Studies—A Review

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Medicinal Plants

Part of the book series: Sustainable Development and Biodiversity ((SDEB,volume 28))

Abstract

Solidago virgaurea L.—a herbaceous perennial found in Europe, Asia and North America, is a source of several important secondary metabolites, which possess great potential for medicinal purposes. The raw material contains a wide spectrum of bioactive compounds including bisdesmosidic phenol glycosides, flavonoids, phenolic acids and their depsides, cis-clerodane-type diterpenes, oleanane-type triterpenoid saponins, the essential oil, and anthocyanins. At present, S. virgaurea has the application as a diuretic, an antispasmodic, an analgesic, and an anti-inflammatory fact in diseases of the urinary system. Earlier, the plant was widely used in traditional medicine. Solidaginis virgaureae herba is used as a diuretic and a disinfectant of the urinary tract. Due to the herb overexploitation from its natural habitats, this taxon has become a rare species in Europe. Nowadays European goldenrod is cultivated in some European countries as a result of agronomic scientific research. Therefore, the method of plant micropropagation and other in-vitro growth systems allow plant biomass to be multiplied for phytochemical and biological research. This review presents the unique chemical and pharmaceutical properties of Solidago virgaurea L., a species that differs from other Solidago taxa.

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References

  • Bader G, Binder K, Hiller K, Ziegler-Bohme H (1987) Zur antimyzetischen Wirksamkeit von Triterpensaponinen aus Solidago virgaurea L. Pharmazie 42:140

    CAS  PubMed  Google Scholar 

  • Bader G, Wray V, Hiller K (1992) Virgaurea-saponin 3, a 3, 28-bisdesmosidic triterpenoid saponin from Solidago virgaurea. Phytochemistry 31:621–623

    Article  CAS  PubMed  Google Scholar 

  • Bader G, Wray V, Hiller K (1995) The main saponins from the aerial parts and the roots of Solidago virgaurea subsp. virgaurea. Planta Med 61:158–161

    Article  CAS  PubMed  Google Scholar 

  • Bajkacz S, Baranowska I, Buszewski B, Kowalski B, Ligor M (2018) Determination of flavonoids and phenolic acids in plant materials using SLE-SPE-UHPLC-MS/MS method. Food Anal Methods 11:3563–3575

    Article  Google Scholar 

  • Björkman O, Holmgren P (1958) Preliminary observations on anthocyanins and other flavonoid compounds and respiration rates in different ecotypes of Solidago virgaurea. Physiol Plant 11:54–157

    Article  Google Scholar 

  • Björkman O, Holmgren P (1960) Polyphenols and polyphenol oxidases in leaves of Solidago virgaurea. Physiol Plant 13:582–594

    Article  Google Scholar 

  • Bohr C, Plescher A (1997) Empfehlungen für den Anbau von Echler Goldrute (Solidago virgaurea L.) in Thüringen. Drogenreport 10(18):24–27

    Google Scholar 

  • Bohr Ch, Plescher A (1999) Optimation of the cultivation parameters of golden rod (Solidago virgaurea L.) relating to the yield of active compounds. Drogenreport 9(14):28

    Google Scholar 

  • Borchert VE, Czyborra P, Fetscher C, Goepel M, Michel MC (2004) Extracts from Rhois aromatic and Solidaginis virgaurea inhibit rat and human bladder contraction. Naunyn Schmiedeberg’s Arch Pharmacol 369:281–186

    Article  CAS  Google Scholar 

  • Borkowski B, Skrzypczakowa L (1962) Związki wielofenolowe w krajowych gatunkach nawłoci Solidago L. Acta Pol Pharm 19:491–495

    CAS  PubMed  Google Scholar 

  • Brantner A (1999) Die antimikrobielle Wirkung von Solidago-haltigen Phytourologica. Drogenreport 12:27–28

    Google Scholar 

  • Brantner AH. Antibakterielle Wirkunf von Solidagoextrakt-hältigen Urologika. http://www.agrar.hu-berlin.de/pflanzenbau/pflanz/themal

  • Budzianowski J, Skrzypczak L, Wesołowska M (1988) Studies on the genus Solidago L II. Phenolic compounds in taxonomy of Solidago canadensis L. Acta Biol Cracov Ser Bot 30:33–37

    Google Scholar 

  • Budzianowski J, Skrzypczak L, Wesołowska M (1990) Flavonoids and leiocarposide in four Solidago taxa. Sci Pharm (wien) 58:15–23

    CAS  Google Scholar 

  • Budzianowski J (1999) Die urologische Wirkung des Leiocarposids. Drogenreport 12:20–21

    Google Scholar 

  • Chen SL, Yu H, Luo HM, Wu Q, Li ChF, Steinmetz A (2016) Conservation and sustainable use of medicinal plants. Chin Med 11:1–10

    Google Scholar 

  • Chodera A, Dabrowska K, Seńczuk M, Wasik-Olejnik A, Skrzypczak L, Budzianowski J, Ellnein- Wojtaszek M (1985) Badania nad działaniem diuretycznym estrowego glukozydu z rodzaju Solidago L. Acta Polon Pharm 42:199–204

    Google Scholar 

  • Chodera A, Dąbrowska K, Skrzypczak L, Budzianowski J (1986) Dalsze badania nad działaniem diuretycznym lejokarpozydu. Acta Polon Pharm 43:499–503

    Google Scholar 

  • Chodera A, Dąbrowska K, Bobkiewicz-Kozłowska T, Tkaczyk J, Skrzypczak L, Budzianowski J (1988) Wpływ lejokarpozydu na doświadczalną kamicę moczową u szczurów. Acta Polon Pharm 45:181–185

    Google Scholar 

  • Chodera A, Dąbrowska K, Śloderbach A, Skrzypczak L, Budzianowski J (1991) Wpływ frakcji flawonoidowych z rodzaju Solidago L. na diurezę i poziom elektrolitów. Acta Polon Pharm-Drug Res 48:35–37

    Google Scholar 

  • Debnath M, Malik CP, Bisen PS (2006) Micropropagation: a tool for the production of high quality plant-based medicines. Curr Pharm Biotechnol 7:33–49

    Article  CAS  PubMed  Google Scholar 

  • Demir H, Açik L, Bali EB, Koç LY, Kaynak G (2009) Antioxidant and antimicrobial activities of Solidago virgaurea extracts. Afr J Biotechnol 8(2):274–279

    CAS  Google Scholar 

  • Derda M, Hadaś E, Thiem B (2009) Plant extracts as natural amoebicidal agents. Parasitol Res 104:705–708

    Article  PubMed  Google Scholar 

  • El-Ghazaly M, Khayyal MT, Okpanyi SN, Arens-Corell M (1992) Study of the anti-inflammatory activity of Populus tremula, Solidago virgaurea and Fraxinus excelsior. Arzneim-Forsch/Drug Res 42:333–336

    CAS  Google Scholar 

  • EMEA. European Medicines Agency. Evaluation of Medicines for Human Use. Assessment report on Solidago virgaurea L., herba (2008) London, 4 September 2008 Doc. Ref. EMEA/HMPC/285759/2007

    Google Scholar 

  • European Pharmacopoeia 9.0 (2017) Council of Europe Strasbourg. The monograph European Goldenrod, Solidaginis virgaureae herba 1376–1378

    Google Scholar 

  • Fötsch G, Gründemann E, Pfeifer S, Hiller K, Salzwedel D (1988) Zur struktur von Leiocarposid. Pharmazie 43:278–280

    Google Scholar 

  • Fötsch G, Pfeifer S, Bartoszek M, Franke P, Hiller K (1989) Biotransformation der Phenolglycoside Leiocarposid und Salicin. Pharmazie 44:555–558

    PubMed  Google Scholar 

  • Fujita S (1990) Miscellaneous contributions to the essential oils of plants from various territories. Components of the essential oils of Solidago virgaurea Linn. ssp. Nippon Nogei Kagaku Kaishi 64:1729–1732 (Jpn). Chem Abstr 1991, 114:98252d

    Google Scholar 

  • Goswami A, Barua RN, Sharma RP, Baruah JN, Kulanthaivel P, Herz W (1984) Clerodanes from Solidago virgaurea. Phytochemistry 23:837–841

    Article  CAS  Google Scholar 

  • Gruszczyk M, Kiełtyka A (2005) Yields and raw material quality of Hypericum perforatum L. and Solidago virga aurea L. from one-year and two-year plantations. Herba Pol 51:5–9

    CAS  Google Scholar 

  • Gründemann E, Gil-Rjong K, Hiller K (1979) 1H-und 13C-NMR-spektroskopische Untersuchungen an Leiocarposid, einem neuen Phenologlykosid. Pharmazie 34:430–431

    Google Scholar 

  • Hiller K, Bader G, Dube G (1987) Zur struktur von Virgaureasaponin 2. Pharmazie 42:744–745

    CAS  Google Scholar 

  • Hiller K, Bader G, Schulten H-R (1987a) Virgaureasaponin 1, ein neues bisdesmosidisches Triterpensaponin aus Solidago virgaurea L. Pharmazie 42:541–543

    CAS  Google Scholar 

  • Hiller K, Dube G, Zeigan D (1985) Virgaureosid A-ein neues, bisdesmosidisches Phenolglycosid aus Solidago virgaurea L. Pharmazie 40:795–796

    CAS  Google Scholar 

  • Hiller K, Fötsch G (1986) Zur Guantitativen Verteilung der Phenolglycoside Virgaureosid A und Leiocarposid in Solidago virgaurea L. Pharmazie 41:415–416

    CAS  Google Scholar 

  • Hiller K, Genzel S, Murach M, Franke P (1975) Zur Kenntnis der Saponine der Gattung Solidago. 1 Mitteilung: Über die Saponine von Solidago virgaurea L. Pharmazie 30:188–190

    CAS  PubMed  Google Scholar 

  • Hiller, K., Gil-Rjong, R., Otto, A (1979) Über Die Flavonoide von Solidago virgaurea L. var. leiocarpa (Benth.) A. Gray. Pharmazie 34:571

    Google Scholar 

  • Hirano M, Sakaguchi S, Takahashi K (2017) Phenotypic differentiation of the Solidago virgaurea complex along an elevational gradient: Insights from a common garden experiment and population genetics. Ecol Evol 7:6949–6962

    Article  PubMed  PubMed Central  Google Scholar 

  • Inose Y, Miyase T, Ueno A (1991) Studies on the constituents of Solidago virga-aurea L. I. Structural elucidation of saponins in the herb. Chem Pharm Bull 39:2037–2042

    Article  CAS  Google Scholar 

  • Inose Y, Miyase T, Ueno A (1992) Studies on the constituents of Solidago virga-aurea L. II. Structures of solidagosaponins X-XX. Chem Pharm Bull 40:946–953

    Article  CAS  Google Scholar 

  • Jacker HJ, Voight G, Hiller K (1981) Zum antiexsudativen verhalten einiger triterpensaponine. Pharmazie 37:380–382

    Google Scholar 

  • Jokela K, Galambosi B (1998) Effect of ridge cultivation and plant density on growth and yield of some medicinal plants in Finland. Z Arzn Gew Pfl 3:139–145

    Google Scholar 

  • Kalemba D (1992) Phenolic acids in four Solidago species. Pharmazie 47:471–472

    CAS  Google Scholar 

  • Kalemba D (1998) Constituents of the essential oil of Solidago virgaurea L. Flavour Fragr J 13:373–376

    Article  CAS  Google Scholar 

  • Kalemba D, Góra J, Kurowska A, Lis A, Lasocka I (1993) Polyphenolic compounds in four Solidago species. Acta Pol Pharm- Drug Res 50:441–442

    CAS  Google Scholar 

  • Kalemba D, Thiem B (2004) Constituents of the essentials oils of four micropropagated Solidago species. Flavour Fragr J 19(1):40–43

    Article  CAS  Google Scholar 

  • Kiełtyk P, Mirek Z (2014) Taxonomy of the Solidago virgaurea group (Asteraceae) in Poland, with special reference to variability along an altitudinal gradient. Flora Geobot 49:259–282

    Article  Google Scholar 

  • Kołodziej B (2007) The effect of NPK fertilisation on golden rod (Solidago virgaurea L., ssp. virgaurea) fields and quality parameters. Herba Pol 53:129–134

    Google Scholar 

  • Kołodziej B (2008a) Effect of agrotechnical factors on the field of golden rod (Solidago virgaurea L. ssp. virgaurea). Herba Pol 54(4):28–34

    Google Scholar 

  • Kołodziej B (2008b) Goldenrod (Solidago virgaurea L. ssp. virgaurea) reaction to foliar fertilization. Agro Sci 63(4):1–9

    Google Scholar 

  • Kołodziej B (2008c) The effect of plantation establisment method and Atonik application in goldenrod (Solidago virgaurea L. spp. virgaurea) cultivation. Acta Sci Pol Hortorum Cultus 7(3):33–39

    Google Scholar 

  • Kołodziej B (2009) Optimalisation of mineral fertilization in goldenrod (Solidago virgaurea L. ssp. virgaurea) cultivated for pharmaceutical purposes. Acta Sci Pol, Hortorum Cultus 8(1):27–36

    Google Scholar 

  • Kołodziej B, Kowalski R, Kędzia B (2011) Antibacterial and antimutagenic activity of extracts aboveground parts of three Solidago species: Solidago virgaurea L., Solidago canadensis L., and Solidago gigantea Ait. J Med Plants Res 5(31):6770–6779

    Google Scholar 

  • Kołodziej B, Winiarska S (2005) Nawłoć pospolita (Solidago virgaurea L.)—cenna roślina lecznicza pozyskiwana z upraw polowych. Herba Pol 51:Supplement 1

    Google Scholar 

  • Kołodziej B (2002) The effect of soil material and nitro gen fertilization on growth and development of golden rod (Solidago virga-aurea L.) Folia Hortic 14(1): 187–193

    Google Scholar 

  • Kruk J, Baranowska I, Buszewski B, Bajkacz S, Kowalski B, Ligor M (2019) Flavonoids enantiomer distribution in different parts of goldenrod (Solidago virgaurea L.), lucerne (Medicago sativa L.) and phacelia (Phacelia tanacetifolia Benth.) Chirality 31:138–149

    Google Scholar 

  • Kucharski W, Mordalski R (2006) Optimalisation of nitrogen fertilization in goldenrod (Solidago virgaurea L.) cultivation for raw material. Herba Pol 52:119

    Google Scholar 

  • Lam J (1971) Polyacetylenes of Solidago virgaurea: Their seasonal variation and NMR long-range spin coupling constants. Phytochemistry 10:647–653

    Article  CAS  Google Scholar 

  • Laurençon L, Sarrazin E, Chevalier M, Prêcheur I, Herbette G, Fernandez X (2013) Triterpenoid saponins from the aerial parts of Solidago virgaurea alpestris with inhibiting activity of Candida albicans yeast-hyphal conversion. Phytochemistry 86:103–111

    Google Scholar 

  • Lück L, Schenk R, Weber K, Bader G, Abel G (2000) Wildherkünfte von Solidago virgaurea L. –Erträge und Variabilität morphologischer und phytochemische Merkmale. Z Arzn Gew Pfl 1:20–27

    Google Scholar 

  • Madaus G (1938) Solidago Virga Aurea. In: Madaus Gerhard, Lehrbuch der Biologischen Heilmittel. Abteilung I: Heilpflanzen, Band III. Georg Thieme Verlag, Leipzig 2571–2576

    Google Scholar 

  • Melzig MF (2004) Echtes Goldrutenkraut- ein Klassiker in der urologischen Phytotherapie. Wien Med Wochenschr 154:523–527

    Article  PubMed  Google Scholar 

  • Metzner J, Hirschelmann R, Hiller K (1984) Antiphlogistische und analgetische Wirkungen von Leiocarposid einem phenolischen Bisglucosid aus Solidago virgaurea L. Pharmazie 39:869–870

    Google Scholar 

  • Miyase T, Inose Y, Ueno A (1994) Studies on the constituents of Solidago virga-aurea L. III. Structures of solidagosaponins XXI–XXIX. Chem Pharm Bull 42:617–624

    Article  CAS  Google Scholar 

  • Motaal AA, Ezzat SM, Tadros MG, El-Askary H (2016) In vivo anti-inflammatory ectivity of caffeoylquinic acid derivatives from Solidago virgaurea in rats. Pharm Biol 54(12):2864–2870

    Article  PubMed  CAS  Google Scholar 

  • Móricz ÁM, Jamshidi-Aidji M, Krüzselyi D, Darcsi A, Böszörményi A, Csontos P, Sz B, Ott PG, Morlock GE (2020) Distinction and valorization of 30 root extracts of 5 five goldenrod (Solidago) species. J Chromatogr A 1611:460602

    Article  PubMed  CAS  Google Scholar 

  • Móricz ÁM, Ott PG, Häbe TT, Darcsi A, Böszörményi A, Alberti Á, Krüzselyi D, Csontos P, Béni S, Morlock GE (2016) Effect-directed discovery of bioactive compounds followed by highly targeted characterization, isolation and identification, exemplarily shown for Solidago virgaurea. Anal Chem 88:8202–8209

    Article  PubMed  CAS  Google Scholar 

  • Okpanyi SN, Schirpke-von Panczensky R, Dickson D (1989) Antiphlogistische, analgetische und antipyretische Wirkung unterschiedlicher Pflanzenextrakte und deren Kombination im Tiermodell. Arzneim-Forsch/ Drug Res 39:698–703

    CAS  Google Scholar 

  • Paul JP, Revathy I, Johnson M (2012) In vitro propagation of Solidago virgaurea L. through nodal culture. Res Plant Biol 2(4):8–15; PDR. Physican Desk Reference for Herbal Medicinaes (2000) European Goldenrod. Med Econ 2890291

    Google Scholar 

  • Pepeljnjak S, Kustrak D, Vukusic I (1998) Investigation of the antimycotic activity of Solidago virgaurea and Solidago gigantea extracts. Pharm Pharmacol Lett 8:85–86

    CAS  Google Scholar 

  • Pietta P, Gardana C, Mauri P, Zecca L (1991) High-performance liquid chromatographic analysis of flavonol glycosides of Solidago virgaurea. J Chromatogr A 558:296–301

    Article  CAS  Google Scholar 

  • Poetsch F (1999) Caffeic acid derivatives from Solidago species. Drogenreport 21:15–21

    Google Scholar 

  • Polish Pharmacopoeia 8.0 (2008) Office for Registration of Medicinal Products, Medical Devices and Biocidal Products, Warsaw, Poland

    Google Scholar 

  • Polish Pharmacopoeia 11 (2017) Office for Registration of Medicinal Products, Medical Devices and Biocidal Products, Warsaw, Poland

    Google Scholar 

  • Precheur I, Rolland Y, Hasseine L, Orange F, Morisot A, Landreau A (2020) Solidago virgaurea L. Plant extract targeted against Candida albicans to reduce oral microbial biomass: a double blind randomized trial on healthy adults. Antibiotics (Basel). 25;9(4):137

    Google Scholar 

  • Rola J, Rola H (2010) Solidago spp. biowskaźnikiem występowania odłogów na gruntach rolnych. Fragm Agron 27(3):122–131

    Google Scholar 

  • Rosłon W, Osińska E, Mazur K, Geszprych A (2014) Chemical characteristics of European goldenrod (Solidago virgaurea L. subsp. virgaurea) from natural sites in central and Eastern Poland [Charakterystyka chemiczna nawłoci Pospolitej (Solidago virgaurea L. subsp. virgaurea) ze stanowisk naturalnych w środkowej i Wschodniej Polsce] Acta Scient Pol Hortorum Cultus 13:55–65

    Google Scholar 

  • Różański H, Bobak Ł, Trziszka T (2016) Znaczenie nawłoci (Solidago) w fitoterapii. Meaning of goldenrod (Solidago) in phytotherapy. Herbalism 1(2):160–173

    Google Scholar 

  • Schaser J, Bonaterra GA, Kelber O, Weiser D, Kinscherf R, Metz J (2006) Untersuchung antiinflammatorischer effekte des phytopharmakons Phytodolor® und seiner einzelkomponenten in einem monozyten-testmodel. Persusion 19:76–77

    Google Scholar 

  • Schilcher H (1964) Über das Vorkommen von Flavonoiden und Hydroxyzimtsäuren in Solidago virgaurea L. und Solidago serotina Ait. Die Naturwissenschaften 51:636

    Google Scholar 

  • Schöpke Th, Wray V, Rzazewska B, Hiller K (1991) Bellissaponins BA1 and BA2, acylated saponins from Bellis perennis. Phytochemistry 30:627–631. https://doi.org/10.1016/0031-9422(91)83740-C

    Article  Google Scholar 

  • Skidmor-Roth L (2010) Herbs & natural supplements. Mosby Elsevier, St. Louis, Missouri, pp 306–308

    Google Scholar 

  • Skrzypczak L, Ellnain-Wojtaszek M (1981) 2-β-D-glucopyronosyloxybenzyl-4-β-D-glucopyronosyloxy-2-hydroxy-3-methoxybenzoate of Solidago species (Asteraceae ). Pol J Chem 55:683–685

    CAS  Google Scholar 

  • Skrzypczak L, Wesołowska M, Thiem B, Budzianowski J (1999) XXIII Solidago L. species (goldenrod): in vitro regeneration and biologically active secondary metabolites. In: Bajaj YPS (ed) Biotechnology in agriculture and forestry, vol 43. Medicinal and aromatic plants XI. Springer, Berlin, Heidelberg

    Google Scholar 

  • Skrzypczakowa L (1961) Flawonoidy w zielu nawłoci pospolitej - Solidago virgaurea L. I Wyodrębnienie i identyfikacja 3-rutynozydu kwercetyny (rutyny). Acta Pol Pharm 18:39–48

    CAS  Google Scholar 

  • Skrzypczakowa L (1962) Flawonoidy w zielu nawłoci pospolitej - Solidago virgaurea L. II Wyodrębnienie i identyfikacja dalszych pochodnych flawonolowych. Acta Pol Pharm 19:481–490

    CAS  PubMed  Google Scholar 

  • Sliwinska E, Thiem B (2007) Genome size stability in six medicinal plant species propagated in vitro. Biol Plantarum 51(3):556–558

    Article  Google Scholar 

  • Starks CM, Williams RB, Goering MG, O’Neil-Johnson M, Norman VL, Hu J-F, Garo E, Hough GW, Rice SM, Eldridge GR (2010) Antibacterial clerodane diterpenes from Goldenrod (Solidago virgaurea). Phytochemistry 71:104–109

    Article  CAS  PubMed  Google Scholar 

  • Sztefanov A, Petheő F, Bernáth J, Sárdi É (2002) Comparative Analysis of Hungarian Solidago virga-aurea Populations. Acta Hort 576:53–55

    Article  CAS  Google Scholar 

  • The Plant List (2020) Version 1.1. Published on the Internet. http://www.theplantlist.org/. Accessed Sept 12

  • Thiem B, Goślińska O (2002) Antimicrobial activity of Solidago virgaurea L. fom in vitro cultures. Fitoterapia 73:514–516

    Article  PubMed  Google Scholar 

  • Thiem B, Wesołowska M, Skrzypczak L, Budzianowski J (2001) Phenolic compounds in two Solidago L. species from in vitro culture. J Acta Pol Pharm 58:277–281

    CAS  Google Scholar 

  • Wang Z, Kim JH, Jang YS, Kim CH, Lee J-Y, Lim SS (2017) Anti-obesity effect of Solidago virgaurea var. gigantea extract through regulation of adipogenesis and lipogenesis pathways in high-fat diet-induced obese mice (C57BL/6N). Food Nut Res 61(1):1273479

    Google Scholar 

  • Westendorf J, Vahlensieck W (1981) Spasmolytische und kontraktile Einflüsse eines pflanzlichen Kombinations-präparates auf die glatte Muskular des isolierten Meerschweinchendarms. Arzneim_Forsch/ Drug Res 31:40–43

    Google Scholar 

  • Wittig J, Veit M (1999) Analyse der Flavonolglycoside von “Solidago"-spezies in einem zusammengesetzten Pflanzenextrakt. Drogenreport 12:18–20

    Google Scholar 

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Budzianowski, J., Thiem, B., Kikowska, M. (2021). Solidago virgaurea L.—Chemical Composition, Traditional and Medicinal Use, Pharmaceutical Properties, Potential Applications, and Biotechnological Studies—A Review. In: Ekiert, H.M., Ramawat, K.G., Arora, J. (eds) Medicinal Plants. Sustainable Development and Biodiversity, vol 28. Springer, Cham. https://doi.org/10.1007/978-3-030-74779-4_20

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