Abstract
Primary malignant bone tumor of the diaphysis is less common than tumors over the metaphysis and epiphysis (Buch, et al., Advanced Biomedical Research 3:33, 2014). According to Sim et al., of the one thousand osteosarcoma cases recorded in the Mayo Clinic records, only approximately 7% of the lesions occurred in the diaphysis of long bones (Sim, et al., Orthopedics. 18:19–23, 1995). The incidence of humeral diaphyseal tumor is even less. Therefore, experience in treating tumors at those locations are usually sparse. The goal for limb salvage surgery for those tumors is not so different from tumors at other locations. “Adequate oncological resection” and “optimal reconstruction” to restore maximum function are still fundamental. To highlight key pearls and what we learned over the course, we share a case of primary diaphyseal osteogenic sarcoma over the right humeral diaphysis, treated with intercalary resection and biological reconstruction.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Bertrand TE, Cruz A, Binitie O, Cheong D, Letson GD. Do surgical margins affect local recurrence and survival in extremity, nonmetastatic, high-grade osteosarcoma? Clin Orthop Relat Res. 2016;474(3):677–83.
Buch A, Sawlani V, Chandanwale S, Kumar H. Diaphyseal osteosarcoma with varying histomorphologic patterns. Adv Biomed Res. 2014;3:33.
Chen WM, Wu PK, Chen CF, Chung LH, Liu CL, Chen TH. High-grade osteosarcoma treated with hemicortical resection and biological reconstruction. J Surg Oncol. 2012;105(8):825–9.
Kawaguchi N, Ahmed AR, Matsumoto S, Manabe J, Matsushita Y. The concept of curative margin in surgery for bone and soft tissue sarcoma. Clin Orthop. 2004;419:165–72.
Sim FH, Frassica FJ, Unni KK. Osteosarcoma of the diaphysis of long bones: clinicopathologic features and treatment of 51 cases. Orthopedics. 1995;18(1):19–23.
Wu PK, Chen CF, Chen CM, Cheng YC, Tsai SW, Chen TH, Chen WM. Intraoperative extracorporeal irradiation and frozen treatment on tumor-bearing autografts show equivalent outcomes for biologic reconstruction. Clin Orthop Relat Res. 2018;476(4):877–89.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2022 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Chen, KL., Chen, CM., Wu, PK., Chen, WM. (2022). Biological Reconstruction of the Humeral Diaphysis: Irradiated Autograft. In: Özger, H., Sim, F.H., Puri, A., Eralp, L. (eds) Orthopedic Surgical Oncology For Bone Tumors . Springer, Cham. https://doi.org/10.1007/978-3-030-73327-8_43
Download citation
DOI: https://doi.org/10.1007/978-3-030-73327-8_43
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-73326-1
Online ISBN: 978-3-030-73327-8
eBook Packages: MedicineMedicine (R0)