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The Effects of Ivy (Hedera helix) on Respiratory Problems and Cough in Humans: A Review

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Natural Products and Human Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1328))

Abstract

Hedera helix (ivy) belongs to the genus Hedera of the Araliaceae family. The leaf of this plant has several active ingredients with medicinal uses. The active constituents of H. helix include monodesmoside α-hederin, hederacoside B, hederacoside C, and hederacoside D.

H. helix leave have been used for the treatment of cough and respiratory problems, and now, other uses have emerged. As a medicinal plant, H. helix has been approved by the German Commission E due to its antispasmodic, spasmolytic, antimicrobial, anti-inflammatory, anthelmintic, antioxidative, antitumor, and antileishmanial activities. It comes with several formulations, including tablets, liquids, and topical ointments. In this review, we focus on the respiratory effects of tablet and liquid forms of H. helix.

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Competing Interests

None

Funding

 The authors would like to thank the Research Deputy at the Mashhad University of Medical Sciences. 

Author information

Authors and Affiliations

  1. Department of Clinical Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Hamed Baharara & Amir Hooshang Mohammadpour

  2. Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Ali Tafazoli Moghadam

  3. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  4. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  5. Polish Mother’s Memorial Hospital Research Institute (PMMHRI), Lodz, Poland

    Amirhossein Sahebkar

  6. Halal Research Center of IRI, FDA, Tehran, Iran

    Amirhossein Sahebkar

  7. Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Seyed Ahmad Emami

  8. Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Seyed Ahmad Emami

  9. Faculty of Medicine, Azad University of Mashhad, Mashhad, Iran

    Tara Tayebi

  10. Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Amir Hooshang Mohammadpour

Authors
  1. Hamed Baharara
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  2. Ali Tafazoli Moghadam
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  3. Amirhossein Sahebkar
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  4. Seyed Ahmad Emami
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  5. Tara Tayebi
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  6. Amir Hooshang Mohammadpour
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Corresponding authors

Correspondence to Amirhossein Sahebkar , Seyed Ahmad Emami or Amir Hooshang Mohammadpour .

Editor information

Editors and Affiliations

  1. Pharmacy, Medical Biotechnology, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  2. Diabetes, Endocrinology & Metabolism, The University of Hull, Brough, UK

    Thozhukat Sathyapalan

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Baharara, H., Moghadam, A.T., Sahebkar, A., Emami, S.A., Tayebi, T., Mohammadpour, A.H. (2021). The Effects of Ivy (Hedera helix) on Respiratory Problems and Cough in Humans: A Review. In: Sahebkar, A., Sathyapalan, T. (eds) Natural Products and Human Diseases. Advances in Experimental Medicine and Biology(), vol 1328. Springer, Cham. https://doi.org/10.1007/978-3-030-73234-9_23

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