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Protective Effects of Curcumin in the Reproductive System: Anti-toxic, Semen Cryopreservative, and Contraceptive Actions

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Book cover Natural Products and Human Diseases

Part of the book series: Advances in Experimental Medicine and Biology ((PMISB,volume 1328))

Abstract

Human daily exposure to various chemical and biological agents is growing due to modern life, and most of these chronic or acute exposures lead to important recognized toxicities. Multiple tissues and body systems could be affected following these exposures and among them is the human reproductive system, which is very vulnerable to toxins. Here we focus mainly on the male reproductive system, and available data show that various exogenous materials could have negative effects on male reproductive parameters. Interestingly, the well-known antioxidant natural product curcumin may have properties which could diminish these toxic effects. Curcumin has also shown some promise in the cryoprotection of sperm samples through its antioxidant potential. Finally, limited data exists on the putative contraceptive activity of curcumin. This narrative review aims to appraise the activity of curcumin within these topics through the available data.

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Authors and Affiliations

  1. Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

    Maryam Matbou Riahi

  2. Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran

    Behzad Behnam

  3. Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

    Behzad Behnam

  4. Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran

    Behzad Behnam

  5. Pharmacy & Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK

    Neil C. Henney

  6. Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran

    Tannaz Jamialahmadi

  7. Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

    Tannaz Jamialahmadi

  8. Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  9. Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  10. School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

Authors
  1. Maryam Matbou Riahi
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  2. Behzad Behnam
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  3. Neil C. Henney
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  4. Tannaz Jamialahmadi
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  5. Amirhossein Sahebkar
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Corresponding authors

Correspondence to Behzad Behnam or Amirhossein Sahebkar .

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Editors and Affiliations

  1. Pharmacy, Medical Biotechnology, Mashhad University of Medical Sciences, Mashhad, Iran

    Amirhossein Sahebkar

  2. Diabetes, Endocrinology & Metabolism, The University of Hull, Brough, UK

    Thozhukat Sathyapalan

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Riahi, M.M., Behnam, B., Henney, N.C., Jamialahmadi, T., Sahebkar, A. (2021). Protective Effects of Curcumin in the Reproductive System: Anti-toxic, Semen Cryopreservative, and Contraceptive Actions. In: Sahebkar, A., Sathyapalan, T. (eds) Natural Products and Human Diseases. Advances in Experimental Medicine and Biology(), vol 1328. Springer, Cham. https://doi.org/10.1007/978-3-030-73234-9_15

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