Abstract
The interest in the Enhanced Recovery After Surgery (ERAS) protocols on gastrectomy for cancer is fairly new and mainly comes from Eastern series. Gastrectomy is a major abdominal operation and is still burdened by a 30% overall morbidity and a 4.5% mortality. The ERAS protocol aims to optimize the patient’s condition and reduce surgical and anesthesiologic stress in order to reduce complications and secondarily reduce hospitalization. Two recent meta-analyses evidenced a reduction in length of hospital stay, bowel recovery and cost reduction, while also reporting, however, a higher risk for readmission in patients treated with an ERAS protocol. In this chapter we discuss the importance of implementing a multidisciplinary team focusing on gastrectomy-specific items starting from preoptimization up to discharge. Preoptimization should focus on inspiratory muscle training and optimization of the nutritional status, especially for patients undergoing neoadjuvant treatment. A minimally invasive approach can reduce surgical stress and should be considered in accordance with the current oncological guidelines. Anesthesia should focus on a goal-directed fluid approach and on a defined multimodal analgesia plan. The goal of the postoperative management is an early mobilization and resumption of oral intake through the avoidance of unnecessary tubes. Discharge should be based on defined criteria and the patient’s network.
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References
Mortensen K, Nilsson M, Slim K, et al. Consensus guidelines for enhanced recovery after gastrectomy: Enhanced Recovery After Surgery (ERAS) Society recommendations. Br J Surg. 2014;101(10):1209–29.
Low DE, Allum W, de Manzoni G, et al. Guidelines for perioperative care in esophagectomy: Enhanced Recovery After Surgery (ERAS) Society recommendations. World J Surg. 2019;43(2):299–330.
Changsheng H, Shengli S, Yongdong F. Application of enhanced recovery after surgery (ERAS) protocol in radical gastrectomy: a systemic review and meta-analysis. Postgrad Med J. 2019;96(1135):257–66.
Wee IJY, Syn NL, Shabbir A, et al. Enhanced recovery versus conventional care in gastric cancer surgery: a meta-analysis of randomized and non-randomized controlled trials. Gastric Cancer. 2019;22(3):423–34.
Fumagalli Romario U, Weindelmayer J, Coratti A, et al. Enhanced recovery after surgery in gastric cancer: which are the main achievements from the Italian experience? Updates Surg. 2018;70(2):257–64.
Bolger JC, Loughney L, Tully R, et al. Perioperative prehabilitation and rehabilitation in esophagogastric malignancies: a systematic review. Dis Esophagus. 2019;32(9):doz058. https://doi.org/10.1093/dote/doz058.
Katsura M, Kuriyama A, Takeshima T, et al. Preoperative inspiratory muscle training for postoperative pulmonary complications in adults undergoing cardiac and major abdominal surgery. Cochrane Database Syst Rev. 2015;(10):CD010356. https://doi.org/10.1002/14651858.CD010356.pub2.
Manfredelli S, Delhorme JB, Venkatasamy A, et al. Could a feeding jejunostomy be integrated into a standardized preoperative management of oeso-gastric junction adenocarcinoma? Ann Surg Oncol. 2017;24(11):3324–30.
Davis CH, Ikoma N, Mansfield PF, et al. Comparison of laparoscopy versus mini-laparotomy for jejunostomy placement in patients with gastric adenocarcinoma. Surg Endosc. 2020; https://doi.org/10.1007/s00464-020-08155-6. [Epub ahead of print].
El-Sharkawy AM, Daliya P, Lewis-Lloyd C, et al. Fasting and surgery timing (FaST) audit. Clin Nutr. 2021;40(3):1405–12.
Gianotti L, Biffi R, Sandini M, et al. Preoperative oral carbohydrate load versus placebo in major elective abdominal surgery (PROCY): a randomized, placebo-controlled, multicenter, phase III trial. Ann Surg. 2018;267(4):623–30.
Baiocchi GL, Giacopuzzi S, Reim D, et al. Incidence and grading of complications after gastrectomy for cancer using the GASTRODATA registry: a European retrospective observational study. Ann Surg. 2020;272(5):807–13.
Shin CH, Long DR, McLean D, et al. Effects of intraoperative fluid management on postoperative outcomes. Ann Surg. 2018;267(6):1084–92.
Myles PS, Bellomo R, Corcoran T, et al. Restrictive versus liberal fluid therapy for major abdominal surgery. N Engl J Med. 2018;378(24):2263–74.
Calvo-Vecino JM, Ripollés-Melchor J, Mythen MG, et al. Effect of goal-directed haemodynamic therapy on postoperative complications in low-moderate risk surgical patients: a multicentre randomised controlled trial (FEDORA trial). Br J Anaesth. 2018;120(4):734–44.
Hughes M, Yim I, Deans DAC, et al. Systematic review and meta-analysis of epidural analgesia versus different analgesic regimes following oesophagogastric resection. World J Surg. 2018;42(1):204–10.
Wu Y, Liu F, Tang H, et al. The analgesic efficacy of subcostal transversus abdominis plane block compared with thoracic epidural analgesia and intravenous opioid analgesia after radical gastrectomy. Anesth Analg. 2013;117(2):507–13.
Guo Q, Li R, Wang L, et al. Transversus abdominis plane block versus local anaesthetic wound infiltration for postoperative analgesia: a systematic review and meta-analysis. Int J Clin Exp Med. 2015;8(10):17343–52.
Forsmo HM, Erichsen C, Rasdal A, et al. Randomized controlled trial of extended perioperative counseling in enhanced recovery after colorectal surgery. Dis Colon Rectum. 2018;61(6):724–32.
Wang D, Li T, Yu J, et al. Is nasogastric or nasojejunal decompression necessary following gastrectomy for gastric cancer? A systematic review and meta-analysis of randomised controlled trials. J Gastrointest Surg. 2015;19(1):195–204.
Pacelli F, Rosa F, Marrelli D, et al. Naso-gastric or naso-jejunal decompression after partial distal gastrectomy for gastric cancer. Final results of a multicenter prospective randomized trial. Gastric Cancer. 2014;17(4):725–32.
Weindelmayer J, Mengardo V, Veltri A, et al. Should we still use prophylactic drain in gastrectomy for cancer? A systematic review and meta-analysis. Eur J Surg Oncol. 2020;46(8):1396–403.
Jo DH, Jeong O, Sun JW, et al. Feasibility study of early oral intake after gastrectomy for gastric carcinoma. J Gastric Cancer. 2011;11(2):101–8.
Lassen K, Kjaeve J, Fetveit T, et al. Allowing normal food at will after major upper gastrointestinal surgery does not increase morbidity: a randomized multicenter trial. Ann Surg. 2008;247(5):721–9.
Zhang HW, Sun L, Yang XW, et al. Safety of total gastrectomy without nasogastric and nutritional intubation. Mol Clin Oncol. 2017;7(3):421–6.
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Weindelmayer, J., Mengardo, V., Carlini, M. (2022). ERAS Protocols for Gastrectomy. In: de Manzoni, G., Roviello, F. (eds) Gastric Cancer: the 25-year R-Evolution. Updates in Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-73158-8_30
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DOI: https://doi.org/10.1007/978-3-030-73158-8_30
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