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Inflammatory Bowel Disease

  • Chapter
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Pocket Handbook of GI Pharmacotherapeutics

Part of the book series: Clinical Gastroenterology ((CG))

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Abstract

This chapter covers the following conditions: inflammatory bowel disease, ulcerative colitis, and Crohn’s disease. This chapter includes drug class, brand/trade names, manufacturer, dosage, indications, contraindications/cautions, adverse effects, drug Interactions, pregnancy advice, lactation safety, relative cost of sulfasalazine, mesalamine, olsalazine, balsalazide, glucocorticoids, prednisone, methylprednisolone, hydrocortisone, budesonide, hydrocortisone retention enema, 6-mercaptopurine, azathioprine, methotrexate, cyclosporine, infliximab, adalimumab, certolizumab pegol, natalizumab, vedolizumab, ustekinumab, and tofacitinib.

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Abbreviations

6-MP:

6-Mercaptopurine

anti-TNFα:

Anti-tumor necrosis factor alpha

CBC/diff:

Complete blood count with differential

CD:

Crohn’s disease

ER:

Extended release

IBD:

Inflammatory bowel disease

IR:

Immediate release

MTX:

Methotrexate

NSAID:

Nonsteroidal anti-inflammatory drug

PML:

Progressive multifocal leukoencephalopathy

PPI:

Proton pump inhibitor

PUVA:

Psoralen and ultraviolet A

TB:

Tuberculosis

TPMT:

Thiopurine S-methyltransferase

UC:

Ulcerative colitis

Suggested Reading

  1. AGA Clinical Practice Guidelines on the Management of Mild-to-Moderate Ulcerative Colitis – Gastroenterology. https://www.gastrojournal.org/article/S0016-5085(18)35407-6/fulltext. Accessed 2 Jan 2021.

  2. Anusol-HC Suppository Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/7785/Anusol-HC-Suppository. Accessed 2 Jan 2021.

  3. Remicade Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/2173/Remicade. Accessed 3 Jan 2021.

  4. Balsalazide Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/2345/balsalazide. Accessed 2 Jan 2021.

  5. Canasa Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/3513/Canasa. Accessed 2 Jan 2021.

  6. Cimzia Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/4782/Cimzia. Accessed 2 Jan 2021.

  7. Crohn’s Clinical Care Pathway. https://cpms.bbinfotech.com/clients/aga_web_tools/interactive_0000542.html. Accessed 2 Jan 2021.

  8. Colman RJ, Rubin DT. Optimal doses of methotrexate combined with anti-TNF therapy to maintain clinical remission in inflammatory bowel disease. J Crohn’s Colitis. 2015;9(4):312–7. https://doi.org/10.1093/ecco-jcc/jjv027.

    Article  Google Scholar 

  9. Dipentum Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/64610/Dipentum/Monograph. Accessed 2 Jan 2021.

  10. Drugs and Lactation Database (LactMed). National Library of Medicine (US), 2006.

    Google Scholar 

  11. Entocort EC Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/260010/Entocort-EC/Monograph. Accessed 2 Jan 2021.

  12. Entyvio Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/6908/Entyvio. Accessed 2 Jan 2021.

  13. FDA Label Search. https://labels.fda.gov/. Accessed 2 Jan 2021.

  14. Feuerstein JD, et al. AGA clinical practice guidelines on the management of moderate to severe ulcerative colitis. Gastroenterology. 2020;158(5):1450–61. https://doi.org/10.1053/j.gastro.2020.01.006.

    Article  PubMed  Google Scholar 

  15. Gengraf Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/4183/Gengraf. Accessed 2 Jan 2021.

  16. Humira Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/3300/adalimumab. Accessed 2 Jan 2021.

  17. Inflammatory Bowel Disease in Pregnancy Clinical Care Pathway: A Report From the American Gastroenterological Association IBD Parenthood Project Working Group – Gastroenterology. https://www.gastrojournal.org/article/S0016-5085(18)35437-4/fulltext. Accessed 2 Jan 2021.

  18. Lichtenstein GR, et al. ACG clinical guideline: management of Crohn’s disease in adults. J Am Coll Gastroenterol. 2018;113(4):481–517. https://doi.org/10.1038/ajg.2018.27.

    Article  Google Scholar 

  19. Mesalamine Adult Dosing – Epocrates Online. https://online.epocrates.com/drugs/411/mesalamine?MultiBrandAlert=true. Accessed 2 Jan 2021.

  20. Otrexup Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/6848/Otrexup. Accessed 2 Jan 2021.

  21. Prednisone Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/27310/prednisone/Monograph. Accessed 2 Jan 2021.

  22. Purinethol Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/202110/Purinethol/Monograph. Accessed 2 Jan 2021.

  23. Rowasa Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/2005/Rowasa. Accessed 2 Jan 2021.

  24. Rubin DT, et al. ACG clinical guideline: ulcerative colitis in adults. J Am Coll Gastroenterol. 2019;114(3):384–413. https://doi.org/10.14309/ajg.0000000000000152.

    Article  Google Scholar 

  25. Simponi Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/4994/Simponi. Accessed 2 Jan 2021.

  26. Stelara Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/5577/ustekinumab. Accessed 2 Jan 2021.

  27. Sulfasalazine Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/28410/sulfasalazine/Monograph. Accessed 2 Jan 2021.

  28. The Current Role of Methotrexate in Patients With Inflammatory Bowel Disease – Gastroenterology & Hepatology. https://www.gastroenterologyandhepatology.net/archives/january-2020/the-current-role-of-methotrexate-in-patients-with-inflammatory-bowel-disease/. Accessed 29 Dec 2020.

  29. Tysabri Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/4014/Tysabri. Accessed 2 Jan 2021.

  30. Uceris Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/6544/Uceris. Accessed 2 Jan 2021.

  31. Ulcerative Colitis Clinical Care Pathway. https://s3.amazonaws.com/agaassets/pdf/guidelines/UlcerativeColitis/index.html. Accessed 2 Jan 2021.

  32. Xeljanz Entire Monograph – Epocrates Online. https://online.epocrates.com/drugs/6514/Xeljanz. Accessed 2 Jan 2021.

  33. Ulcerative Colitis. https://s3.amazonaws.com/agaassets/pdf/guidelines/UlcerativeColitis/index.html. Accessed 2 Jan 2021.

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Author information

Authors and Affiliations

  1. Gastroenterology-Hepatology Fellowship Program, University of Connecticut Health Center, Farmington, CT, USA

    Sanket Patel

  2. Division of Gastroenterology & Hepatology, University of Connecticut Health Center, Farmington, CT, USA

    Haleh Vaziri

Authors
  1. Sanket Patel
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  2. Haleh Vaziri
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Corresponding author

Correspondence to Haleh Vaziri .

Editor information

Editors and Affiliations

  1. Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT, USA

    Marianna G. Mavilia

  2. Medicine, Division of Gastroenterology-Hepatology, University of Connecticut Health Center, Farmington, CT, USA

    George Y. Wu

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Patel, S., Vaziri, H. (2021). Inflammatory Bowel Disease. In: Mavilia, M.G., Wu, G.Y. (eds) Pocket Handbook of GI Pharmacotherapeutics. Clinical Gastroenterology. Humana, Cham. https://doi.org/10.1007/978-3-030-72592-1_5

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  • DOI: https://doi.org/10.1007/978-3-030-72592-1_5

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-72591-4

  • Online ISBN: 978-3-030-72592-1

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