Abstract
Automating retinal vessel segmentation is a primary element of computer-aided diagnostic systems for many retinal diseases. It facilitates the inspection of shape, width, tortuosity, and other blood vessel characteristics. In this paper, a new method that incorporates Distorted Gaussian Matched Filters (D-GMFs) with adaptive parameters as part of a Deep Convolutional Architecture is proposed. The D-GaussianNet includes D-GMF units, a variant of the Gaussian Matched Filter that considers curvature, placed at the beginning and end of the network to implicitly indicate that spatial attention should focus on curvilinear structures in the image. Experimental results on datasets DRIVE, STARE, and CHASE show state-of-the-art performance with an accuracy of 0.9565, 0.9647, and 0.9609 and a F1-score of 0.8233, 0.8141, and 0.8077, respectively.
This work is partially supported by CONACyT, Mexico (Doctoral Studies Grants no. 626155 and 626154).
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References
Abramoff, M.D., Garvin, M.K., Sonka, M.: Retinal imaging and image analysis. IEEE Rev. Biomed. Eng. 3, 169ā208 (2010)
Acar, E., Yilmaz, I.: Covid-19 detection on IBM quantum computer with classical-quantum transfer learning. medRxiv (2020)
Amil, P., Reyes-Manzano, C.F., GuzmƔn-Vargas, L., SendiƱa-Nadal, I., Masoller, C.: Network-based features for retinal fundus vessel structure analysis. PloS one 14(7), e0220132 (2019)
Badawi, S.A., Fraz, M.M.: Optimizing the trainable B-COSFIRE filter for retinal blood vessel segmentation. PeerJ 6, e5855 (2018)
Chalakkala, R.J., Abdullaa, W.H., Hongb, S.C.: Fundus retinal image analyses for screening and diagnosing diabetic retinopathy, macular edema, and glaucoma disorders. Diabetes and Fundus OCT, p. 59 (2020)
Chaudhuri, S., Chatterjee, S., Katz, N., Nelson, M., Goldbaum, M.: Detection of blood vessels in retinal images using two-dimensional matched filters. IEEE Transactions on medical imaging 8(3), 263ā269 (1989)
Condurache, A.P., Mertins, A.: Segmentation of retinal vessels with a hysteresis binary-classification paradigm. Comput. Medi. Imaging Graph. 36(4), 325ā335 (2012)
Cruz-Aceves, I., Cervantes-Sanchez, F., Avila-Garcia, M.S.: A novel multiscale gaussian-matched filter using neural networks for the segmentation of x-ray coronary angiograms. J. Healthcare Eng. 2018 (2018). https://doi.org/10.1155/2018/5812059
Feng, S., Zhuo, Z., Pan, D., Tian, Q.: CcNet: a cross-connected convolutional network for segmenting retinal vessels using multi-scale features. Neurocomputing 392, 268ā276 (2020)
Fraz, M.M., et al.: Ensemble classification system applied for retinal vessel segmentation on child images containing various vessel profiles. In: Campilho, A., Kamel, M. (eds.) Image Analysis and Recognition, pp. 380ā389. Springer, Heidelberg (2012)
Fu, Q., Li, S., Wang, X.: MSCNN-AM:: a multi-scale convolutional neural network with attention mechanisms for retinal vessel segmentation. IEEE Access 8, 163926ā163936 (2020)
Geng, L., Li, P., Zhu, W., Chen, X.: M2E-Net: multiscale morphological enhancement network for retinal vessel segmentation. In: Pen, Y., et al. (eds.) PRCV 2020, Part. LNCS, vol. 12305, pp. 493ā502. Springer, Cham (2020). https://doi.org/10.1007/978-3-030-60633-6_41
He, K., Zhang, X., Ren, S., Sun, J.: Deep residual learning for image recognition. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 770ā778 (2016)
Heidari, S., Naseri, M., Nagata, K.: Quantum selective encryption for medical images. Int. J. Theor. Phys. 58(11), 3908ā3926 (2019)
Henderson, M., Shakya, S., Pradhan, S., Cook, T.: Quanvolutional neural networks: powering image recognition with quantum circuits. Quant. Mach. Intell. 2(1), 1ā9 (2020). https://doi.org/10.1007/s42484-020-00012-y
Hoover, A., Kouznetsova, V., Goldbaum, M.: Locating blood vessels in retinal images by piecewise threshold probing of a matched filter response. IEEE Trans. Med. Imaging 19(3), 203ā210 (2000)
Huang, G., Liu, Z., Van Der Maaten, L., Weinberger, K.Q.: Densely connected convolutional networks. In: Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, pp. 4700ā4708 (2017)
Jiang, Z., Zhang, H., Wang, Y., Ko, S.B.: Retinal blood vessel segmentation using fully convolutional network with transfer learning. Comput. Med. Imaging Graph. 68, 1ā15 (2018)
Jin, Q., Meng, Z., Pham, T.D., Chen, Q., Wei, L., Su, R.: DUNet: a deformable network for retinal vessel segmentation. Knowl.-Based Syst. 178, 149ā162 (2019)
Khan, M.A.U., Khan, T.M., Bailey, D.G., Soomro, T.A.: A generalized multi-scale line-detection method to boost retinal vessel segmentation sensitivity. Pattern Anal. Appl. 22(3), 1177ā1196 (2018). https://doi.org/10.1007/s10044-018-0696-1
Li, L., Verma, M., Nakashima, Y., Nagahara, H., Kawasaki, R.: Iternet: retinal image segmentation utilizing structural redundancy in vessel networks. In: The IEEE Winter Conference on Applications of Computer Vision, pp. 3656ā3665 (2020)
Liew, G., Wang, J.J.: Retinal vascular signs: a window to the heart? Revista EspaƱola de Cardiologia 64(6), 515ā521 (2011)
Liskowski, P., Krawiec, K.: Segmenting retinal blood vessels with deep neural networks. IEEE Trans. Med. Imaging 35(11), 2369ā2380 (2016)
Maharana, D.K., Das, P.: Automatic extraction of vessels from newly accessible dataset. In: Soft Computing: Theories and Applications, pp. 1139ā1150. Springer (2020). https://doi.org/10.1007/978-981-15-0751-9_105
Mo, J., Zhang, L.: Multi-level deep supervised networks for retinal vessel segmentation. Int. J. Comput. Assist. Radiol. Surg. 12(12), 2181ā2193 (2017). https://doi.org/10.1007/s11548-017-1619-0
Pal, S., Chatterjee, S., Dey, D., Munshi, S.: Morphological operations with iterative rotation of structuring elements for segmentation of retinal vessel structures. Multidimens. Syst. Signal Process. 30(1), 373ā389 (2018). https://doi.org/10.1007/s11045-018-0561-9
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Navab, N., Hornegger, J., Wells, W.M., Frangi, A.F. (eds.) MICCAI 2015 Part III. LNCS, vol. 9351, pp. 234ā241. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Sazak, Ć., Nelson, C.J., Obara, B.: The multiscale bowler-hat transform for blood vessel enhancement in retinal images. Pattern Recognit. 88, 739ā750 (2019)
Birgui Sekou, T., Hidane, M., Olivier, J., Cardot, H.: Retinal blood vessel segmentation using a fully convolutional network ā transfer learning from patch- to image-level. In: Shi, Y., Suk, H.-I., Liu, M. (eds.) MLMI 2018. LNCS, vol. 11046, pp. 170ā178. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00919-9_20
Simard, P.Y., Steinkraus, D., Platt, J.C., et al.: Best practices for convolutional neural networks applied to visual document analysis. In: ICDAR, vol. 3 (2003)
Smith, L.N.: Cyclical learning rates for training neural networks. In: 2017 IEEE Winter Conference on Applications of Computer Vision (WACV), pp. 464ā472. IEEE (2017)
Soomro, T.A., Khan, T.M., Khan, M.A., Gao, J., Paul, M., Zheng, L.: Impact of ICA-based image enhancement technique on retinal blood vessels segmentation. IEEE Access 6, 3524ā3538 (2018)
Staal, J., Abramoff, M., Niemeijer, M., Viergever, M., van Ginneken, B.: Ridge based vessel segmentation in color images of the retina. IEEE Trans. Med. Imaging 23(4), 501ā509 (2004)
Tamim, N., Elshrkawey, M., Abdel Azim, G., Nassar, H.: Retinal blood vessel segmentation using hybrid features and multi-layer perceptron neural networks. Symmetry 12(6), 894 (2020)
Trujillo, M.C.R., AlarcĆ³n, T.E., Dalmau, O.S., Ojeda, A.Z.: Segmentation of carbon nanotube images through an artificial neural network. Soft Comput. 21(3), 611ā625 (2017)
Wang, X., Jiang, X.: Retinal vessel segmentation by a divide-and-conquer funnel-structured classification framework. Signal Process. 165, 104ā114 (2019)
Zapata, M.A., et al.: Artificial intelligence to identify retinal fundus images, quality validation, laterality evaluation, macular degeneration, and suspected glaucoma. Clin. Ophthalmol. 14, 419 (2020). (Auckland, NZ)
Zhang, A., Wang, K.C., Yang, E., Li, J.Q., Chen, C., Qiu, Y.: Pavement lane marking detection using matched filter. Measurement 130, 105ā117 (2018)
Zhang, Z., Liu, Q., Wang, Y.: Road extraction by deep residual u-net. IEEE Geosci. Remote Sens. Lett. 15(5), 749ā753 (2018)
ZhaoZhao, J., et al.: Automatic retinal vessel segmentation using multi-scale superpixel chain tracking. Digit. Signal Process. 81, 26ā42 (2018)
Zhou, M., Jin, K., Wang, S., Ye, J., Qian, D.: Color retinal image enhancement based on luminosity and contrast adjustment. IEEE Trans. Biomed. Eng. 65(3), 521ā527 (2017)
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Alvarado-Carrillo, D.E., Ovalle-Magallanes, E., Dalmau-CedeƱo, O.S. (2021). D-GaussianNet: Adaptive Distorted Gaussian Matched Filter with Convolutional Neural Network for Retinal Vessel Segmentation. In: Nguyen, M., Yan, W.Q., Ho, H. (eds) Geometry and Vision. ISGV 2021. Communications in Computer and Information Science, vol 1386. Springer, Cham. https://doi.org/10.1007/978-3-030-72073-5_29
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