Abstract
Since endoscopic ultrasound is uncomfortable and time-consuming, sedation is necessary to improve patient satisfaction and procedure success rate. Although moderate sedation using benzodiazepines and opioids is widely used, dexmedetomidine or propofol sedation is becoming popular. The following three points may increase the burden on the patient and provoke body movement; (1) when passing through the pharynx, (2) when passing through the pylorus, and (3) when shortening the duodenal second portion. Gentle maneuver is needed, and additional sedation should be prepared. It is critical to perform sufficient pre-evaluations for each patient. Elderly patients should receive reduced doses of sedative agents. Additional doses should be carefully considered based on the monitoring and direct observation of the patient’s condition.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Obara K, Haruma K, Irisawa A, Kaise M, Gotoda T, Sugiyama M, et al. Guidelines for sedation in gastroenterological endoscopy. Dig Endosc. 2015;27:435–49.
Lin OS. Sedation for routine gastrointestinal endoscopic procedures: a review on efficacy, safety, efficiency, cost and satisfaction. Intest Res. 2017;15:456–66.
Nishizawa T, Suzuki H, Arita M, Kataoka Y, Fukagawa K, Ohki D, et al. Pethidine dose and female sex as risk factors for nausea after esophagogastroduodenoscopy. J Clin Biochem Nutr. 2018;63:230–2.
Nishizawa T, Sakitani K, Suzuki H, Takeuchi M, Takahashi Y, Takeuchi K, et al. Adverse events associated with bidirectional endoscopy with midazolam and pethidine. J Clin Biochem Nutr. 2019;65:1–4.
Horn E, Nesbit SA. Pharmacology and pharmacokinetics of sedatives and analgesics. Gastrointest Endosc Clin N Am. 2004;14:247–68.
Wu W, Chen Q, Zhang LC, Chen WH. Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy. J Int Med Res. 2014;42:516–22.
Nishizawa T, Suzuki H, Sagara S, Kanai T, Yahagi N. Dexmedetomidine versus midazolam for gastrointestinal endoscopy: a meta-analysis. Dig Endosc. 2015;27:8–15.
Shafer A, Doze VA, Shafer SL, White PF. Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. Anesthesiology. 1988;69:348–56.
Qadeer MA, Vargo JJ, Khandwala F, Lopez R, Zuccaro G. Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. Clin Gastroenterol Hepatol. 2005;3:1049–56.
Nishizawa T, Suzuki H. Propofol for gastrointestinal endoscopy. United European Gastroenterol J. 2018;6:801–5.
Nishizawa T, Suzuki H, Hosoe N, Ogata H, Kanai T, Yahagi N. Dexmedetomidine vs propofol for gastrointestinal endoscopy: a meta-analysis. United European Gastroenterol J. 2017;5:1037–45.
Bo LL, Bai Y, Bian JJ, Wen PS, Li JB, Deng XM. Propofol vs traditional sedative agents for endoscopic retrograde cholangiopancreatography: a meta-analysis. World J Gastroenterol. 2011;17:3538–43.
Nishizawa T, Suzuki H, Matsuzaki J, Kanai T, Yahagi N. Propofol versus traditional sedative agents for endoscopic submucosal dissection. Dig Endosc. 2014;26:701–6.
Wang D, Chen C, Chen J, Xu Y, Wang L, Zhu Z, et al. The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. PLoS One. 2013;8:e53311.
Triantafillidis JK, Merikas E, Nikolakis D, Papalois AE. Sedation in gastrointestinal endoscopy: current issues. World J Gastroenterol. 2013;19:463–81.
Nakai Y, Kogure H, Matsubara S, Isayama H, Koike K. Sedation for “triple-win” endoscopic ultrasonography. Endosc Digest. 2017;29:1100–1.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Nishizawa, T., Suzuki, H. (2021). Sedation for Endoscopic Ultrasound. In: Facciorusso, A., Muscatiello, N. (eds) Endoscopic Ultrasound Management of Pancreatic Lesions. Springer, Cham. https://doi.org/10.1007/978-3-030-71937-1_18
Download citation
DOI: https://doi.org/10.1007/978-3-030-71937-1_18
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-71936-4
Online ISBN: 978-3-030-71937-1
eBook Packages: MedicineMedicine (R0)