Skip to main content

Sedation for Endoscopic Ultrasound

  • Chapter
  • First Online:
Endoscopic Ultrasound Management of Pancreatic Lesions

Abstract

Since endoscopic ultrasound is uncomfortable and time-consuming, sedation is necessary to improve patient satisfaction and procedure success rate. Although moderate sedation using benzodiazepines and opioids is widely used, dexmedetomidine or propofol sedation is becoming popular. The following three points may increase the burden on the patient and provoke body movement; (1) when passing through the pharynx, (2) when passing through the pylorus, and (3) when shortening the duodenal second portion. Gentle maneuver is needed, and additional sedation should be prepared. It is critical to perform sufficient pre-evaluations for each patient. Elderly patients should receive reduced doses of sedative agents. Additional doses should be carefully considered based on the monitoring and direct observation of the patient’s condition.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

References

  1. Obara K, Haruma K, Irisawa A, Kaise M, Gotoda T, Sugiyama M, et al. Guidelines for sedation in gastroenterological endoscopy. Dig Endosc. 2015;27:435–49.

    Article  Google Scholar 

  2. Lin OS. Sedation for routine gastrointestinal endoscopic procedures: a review on efficacy, safety, efficiency, cost and satisfaction. Intest Res. 2017;15:456–66.

    Article  Google Scholar 

  3. Nishizawa T, Suzuki H, Arita M, Kataoka Y, Fukagawa K, Ohki D, et al. Pethidine dose and female sex as risk factors for nausea after esophagogastroduodenoscopy. J Clin Biochem Nutr. 2018;63:230–2.

    Article  Google Scholar 

  4. Nishizawa T, Sakitani K, Suzuki H, Takeuchi M, Takahashi Y, Takeuchi K, et al. Adverse events associated with bidirectional endoscopy with midazolam and pethidine. J Clin Biochem Nutr. 2019;65:1–4.

    Google Scholar 

  5. Horn E, Nesbit SA. Pharmacology and pharmacokinetics of sedatives and analgesics. Gastrointest Endosc Clin N Am. 2004;14:247–68.

    Article  Google Scholar 

  6. Wu W, Chen Q, Zhang LC, Chen WH. Dexmedetomidine versus midazolam for sedation in upper gastrointestinal endoscopy. J Int Med Res. 2014;42:516–22.

    Article  CAS  Google Scholar 

  7. Nishizawa T, Suzuki H, Sagara S, Kanai T, Yahagi N. Dexmedetomidine versus midazolam for gastrointestinal endoscopy: a meta-analysis. Dig Endosc. 2015;27:8–15.

    Article  Google Scholar 

  8. Shafer A, Doze VA, Shafer SL, White PF. Pharmacokinetics and pharmacodynamics of propofol infusions during general anesthesia. Anesthesiology. 1988;69:348–56.

    Article  CAS  Google Scholar 

  9. Qadeer MA, Vargo JJ, Khandwala F, Lopez R, Zuccaro G. Propofol versus traditional sedative agents for gastrointestinal endoscopy: a meta-analysis. Clin Gastroenterol Hepatol. 2005;3:1049–56.

    Article  CAS  Google Scholar 

  10. Nishizawa T, Suzuki H. Propofol for gastrointestinal endoscopy. United European Gastroenterol J. 2018;6:801–5.

    Article  CAS  Google Scholar 

  11. Nishizawa T, Suzuki H, Hosoe N, Ogata H, Kanai T, Yahagi N. Dexmedetomidine vs propofol for gastrointestinal endoscopy: a meta-analysis. United European Gastroenterol J. 2017;5:1037–45.

    Article  CAS  Google Scholar 

  12. Bo LL, Bai Y, Bian JJ, Wen PS, Li JB, Deng XM. Propofol vs traditional sedative agents for endoscopic retrograde cholangiopancreatography: a meta-analysis. World J Gastroenterol. 2011;17:3538–43.

    Article  Google Scholar 

  13. Nishizawa T, Suzuki H, Matsuzaki J, Kanai T, Yahagi N. Propofol versus traditional sedative agents for endoscopic submucosal dissection. Dig Endosc. 2014;26:701–6.

    Article  Google Scholar 

  14. Wang D, Chen C, Chen J, Xu Y, Wang L, Zhu Z, et al. The use of propofol as a sedative agent in gastrointestinal endoscopy: a meta-analysis. PLoS One. 2013;8:e53311.

    Article  CAS  Google Scholar 

  15. Triantafillidis JK, Merikas E, Nikolakis D, Papalois AE. Sedation in gastrointestinal endoscopy: current issues. World J Gastroenterol. 2013;19:463–81.

    Article  CAS  Google Scholar 

  16. Nakai Y, Kogure H, Matsubara S, Isayama H, Koike K. Sedation for “triple-win” endoscopic ultrasonography. Endosc Digest. 2017;29:1100–1.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hidekazu Suzuki .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Nishizawa, T., Suzuki, H. (2021). Sedation for Endoscopic Ultrasound. In: Facciorusso, A., Muscatiello, N. (eds) Endoscopic Ultrasound Management of Pancreatic Lesions. Springer, Cham. https://doi.org/10.1007/978-3-030-71937-1_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-71937-1_18

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-71936-4

  • Online ISBN: 978-3-030-71937-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics