Abstract
Against the pathogen threats, the pulmonary immune system (PIS) acts systemically, by executing a series of strategies. At the first it detects and blocks the intruder; then, it activates and recruits the immune cells; and finally, it kills and evacuates the damage. On its side, the virus is diversifying techniques to evade the PIS, enter to the cells and replicate. This relationship makes the two in a game situation that takes place on several rounds. The goal of the present work, is to design a game theory model, by establishing the strategies of each player, the payoffs at the end of each round, and the winner after a high number of rounds. We prove that our model relates six parameters: four to assess the probabilities of success of the strategies, replication rate and winning player. After that, we show that we can estimate the value of one parameter, if the other five parameters are known.
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Lakhal, S., Guennoun, Z. (2021). Covid-19 and the Pulmonary Immune System Fight: A Game Theory Model. In: Abraham, A., Piuri, V., Gandhi, N., Siarry, P., Kaklauskas, A., Madureira, A. (eds) Intelligent Systems Design and Applications. ISDA 2020. Advances in Intelligent Systems and Computing, vol 1351. Springer, Cham. https://doi.org/10.1007/978-3-030-71187-0_47
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