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Quality of Life in Peritoneal Dialysis

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Applied Peritoneal Dialysis

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Abstract

End-stage kidney disease (ESKD) is a chronic medical condition with a significant symptom burden. Treatment with kidney replacement therapies, including peritoneal dialysis (PD), can improve survival and ameliorate the complications and consequences of ESKD but do not provide a ‘cure’. For many patients, some of whom may be on dialysis for life, the quality, rather than duration of life, is increasingly important. Health-related quality of life (HRQOL) is a concept that relates to the impact of both the disease and its treatment on a patient’s physical, functional, social and psychological well-being. HRQOL is an important outcome measure in patients on PD – it correlates with outcomes such as mortality and hospitalisation, but it also reflects the patient’s perspective and experience of dialysis. Whilst HRQOL is often overlooked as an outcome measure in favour of assessment of mortality, infection rates or dialysis adequacy, it more closely reflects the subjective patient experience of PD and offers opportunities to optimise an individual patient’s care.

This chapter will focus on definitions of quality of life and measurement tools to assess this, compare quality of life in haemodialysis and peritoneal dialysis and identify a selection of factors that influence HRQOL in PD.

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References

  1. WHOQOL: measuring quality of life. [Online] [Cited: January 2, 2019]. https://www.who.int/healthinfo/survey/whoqol-qualityoflife/en/.

  2. Pais-Ribero JL. Quality of life is a primary-endpoint in clinical settings. Clin Nutr. 2004;23(1):121–30.

    Article  Google Scholar 

  3. Murtagh FE, Addington-Hall J, Higginson IJ. The prevalence of symptoms in end-stage renal disease: a systematic review. Adv Chronic Kidney Dis. 2007;14(1):82–99.

    Article  PubMed  Google Scholar 

  4. Joshi VD. Quality of life in end stage renal disease patients. World J Nephrol. 2014;3(4):308–16.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Cameron JI, et al. Differences in quality of life across renal replacement therapies: a meta-analytic comparison. Am J Kidney Dis. 2000;35(4):629–37.

    Article  CAS  PubMed  Google Scholar 

  6. Mapes DL, et al. Health-related quality of life in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis. 2004;44(5 Suppl 2):54–60.

    Article  PubMed  Google Scholar 

  7. Grincenkov FR, et al. Impact of baseline health-related quality of life scores on survival of incident patients on peritoneal dialysis: a cohort study. Nephron. 2015;129(9):97–103.

    Article  PubMed  Google Scholar 

  8. Manera KE, et al. Standardised outcomes in nephrology—peritoneal dialysis (SONG-PD): study protocol for establishing a core outcome set in PD. Perit Dial Int. 2017;37:639–47.

    Article  PubMed  Google Scholar 

  9. Finkelstein FO, Finkelstein SH. Time to rethink our approach to patient-reported outcome measures for ESRD. Clin J Am Soc Nephrol. 2017;12(11):1885–8.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Mapes DL, et al. Health-related quality of life as a predictor of mortality and hospitalization: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Kidney Int. 2003;64(1):339–49.

    Article  PubMed  Google Scholar 

  11. Ginieri-Coccosis M, et al. Quality of life, mental health and health beliefs in haemodialysis and peritoneal dialysis patients: investigating differences in early and later years of current treatment. BMC Nephrol. 2008;9:14.

    Article  Google Scholar 

  12. Manera KE, et al. Patient and caregiver priorities for outcomes in peritoneal dialysis. Clin J Am Soc Nephrol. 2019;14:74–83.

    Article  PubMed  Google Scholar 

  13. Avramovic M, Stefanovic V. Health-related quality of life in different stages of renal failure. Artif Organs. 2012;36(7):581–9.

    Article  PubMed  Google Scholar 

  14. Hamilton AJ, et al. Psychosocial health and lifestyle behaviors in young adults receiving renal replacement therapy compared to the general population: findings from the SPEAK study. Am J Kidney Dis. 2019;73(2):194–205.

    Article  PubMed  Google Scholar 

  15. Wyld M, et al. A systematic review and meta-analysis of utility-based quality of life in chronic kidney disease treatments. PLoS Med. 2012;9(9):e1001307.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Purnell TS, et al. Comparison of life participation activities among adults treated by hemodialysis, peritoneal dialysis, and kidney transplantation: a systematic review. Am J Kidney Dis. 2013;62(5):953–73.

    Article  PubMed  Google Scholar 

  17. Tian X, et al. The comparison of cognitive function and risk of dementia in CKD patients under peritoneal dialysis and hemodialysis. Medicine. 2019;98(6):e14390.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Griva K, et al. Quality of life and emotional distress between patients on peritoneal dialysis versus community-based hemodialysis. Qual Life Res. 2014;23(1):57–66.

    Article  CAS  PubMed  Google Scholar 

  19. Al Wakeel J, et al. Quality of life in hemodialysis and peritoneal dialysis patients in Saudi Arabia. Ann Saudi Med. 2012;32(6):570–4.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Homaie RE, et al. Health-related quality of life in patients on hemodialysis. A meta-analysis of Iranian studies. Iran J Kidney Dis. 2015;9(5):386–93.

    Google Scholar 

  21. Zazzeroni L, et al. Comparison of quality of life in patients undergoing hemodialysis and peritoneal dialysis: a systematic review and meta-analysis. Kidney Blood Press Res. 2017;42:717–27.

    Article  PubMed  Google Scholar 

  22. Queeley GL, Campbell ES. Comparing treatment modalities for end-stage renal disease: a meta-analysis. Am Health Drug Benefits. 2018;11(3):118–27.

    PubMed  PubMed Central  Google Scholar 

  23. Rocco MV, et al. Cross-sectional study of quality of life and symptoms in chronic renal disease patients: the modification of diet in renal disease study. Am J Kidney Dis. 1997;29(6):888–96.

    Article  CAS  PubMed  Google Scholar 

  24. Mingardi G, et al. Health-related quality of life in dialysis patients. A report from an Italian study using the SF-36 Health Survey. DIA-QOL Group. Nephrol Dial Transplant. 1999;14:1503–10.

    Article  CAS  PubMed  Google Scholar 

  25. Saad MM, et al. Predictors of quality of life in patients with end-stage renal disease on hemodialysis. Int J Nephrol Renovasc Dis. 2015;8:119–23.

    Article  PubMed  PubMed Central  Google Scholar 

  26. Ricardo AC, et al. Sex-related disparities in CKD progression. J Am Soc Nephrol. 2019;30(1):137–46.

    Article  CAS  PubMed  Google Scholar 

  27. Carrero JJ, et al. Chronic kidney disease, gender, and access to care: a global perspective. Semin Nephrol. 2017;37(3):296–308.

    Article  PubMed  Google Scholar 

  28. Bakewell AB, Higgins RM, Edwards ME. Quality of life in peritoneal dialysis patients: decline over time and association with clinical outcomes. Kidney Int. 2002;61(1):239–48.

    Article  PubMed  Google Scholar 

  29. Kutner NG, Zhang R, Brogan D. Race, gender, and incident dialysis patients’ reported health status and quality of life. J Am Soc Nephrol. 2005;16(5):1440–8.

    Article  PubMed  Google Scholar 

  30. Lai C-F, et al. Sexual dysfunction in peritoneal dialysis patients. Am J Nephrol. 2007;27(6):615–21.

    Article  PubMed  Google Scholar 

  31. Udayaraj U, et al. Ethnicity, socioeconomic status, and attainment of clinical practice guideline standards in dialysis patients in the United Kingdom. Clin Am J Soc Nephrol. 2009;4(5):979–87.

    Article  Google Scholar 

  32. van den Beukel TO, et al. The role of psychosocial factors in ethnic differences in survival on dialysis in the Netherland. Nephrol Dial Transplant. 2011;6(1):2472–9.

    Google Scholar 

  33. Hicks LS, et al. Differences in health-related quality of life and treatment preferences among black and white patients with end-stage renal disease. Qual Life Res. 2004;13:1129–37.

    Article  PubMed  Google Scholar 

  34. Bakewell AB, Higgins RM, Edmunds ME. Does ethnicity influence perceived quality of life of patients on dialysis and following renal transplant? Nephrol Dial Transplant. 2001;16(7):1395–401.

    Article  CAS  PubMed  Google Scholar 

  35. Fukuhara S, et al. Health-related quality of life among dialysis patients on three continents: the Dialysis Outcomes and Practice Patterns Study. Kidney Int. 2003;64(5):1903–10.

    Article  PubMed  Google Scholar 

  36. Brown EA, et al. Peritoneal or hemodialysis for the frail elderly patient, the choice of 2 evils? Kidney Int. 2016;91(2):294–303.

    Article  PubMed  Google Scholar 

  37. Ahmed S, et al. Opinions of elderly people on treatment for end-stage renal disease. Gerontology. 1999;45(3):156–9.

    Article  CAS  PubMed  Google Scholar 

  38. Harris SA, et al. Clinical outcomes and quality of life in elderly patients on peritoneal dialysis versus hemodialysis. Perit Dial Int. 2002;22(4):463–70.

    Article  PubMed  Google Scholar 

  39. Brown EA, et al. Broadening Options for Long-term Dialysis in the Elderly (BOLDE): differences in quality of life on peritoneal dialysis compared to haemodialysis for older patients. Nephrol Dial Transplant. 2010;25(11):3755–63.

    Article  PubMed  PubMed Central  Google Scholar 

  40. Iyasere OU, et al. Quality of life and physical function in older patients on dialysis: a comparison of assisted peritoneal dialysis with hemodialysis. Clin J Am Soc Nephrol. 2016;11(3):423–30.

    Article  CAS  PubMed  Google Scholar 

  41. Griva K, et al. Quality of life and emotional distress in patients and burden in caregivers: a comparison between assisted peritoneal dialysis and self-care peritoneal dialysis. Qual Life Res. 2016;25(2):373–84.

    Article  CAS  PubMed  Google Scholar 

  42. dos Santos Grincenkov FR, et al. Longitudinal changes in health-related quality of life scores in Brazilian incident peritoneal dialysis patients (BRAZPD): socio-economic status not a barrier. Perit Dial Int. 2013;33(6):687–96.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Neumann D, et al. Social relationships and their impact on health-related. Nephrol Dial Transplant. 2018;33:1235–44.

    Article  PubMed  Google Scholar 

  44. Bardak S, et al. The other side of the coin in renal replacement therapies: the burden on caregivers. Int Urol Nephrol. 2019;51(2):343–9.

    Article  PubMed  Google Scholar 

  45. Gilbertson EL, et al. Burden of care and quality of life among caregivers for adults receiving maintenance dialysis: a systematic review. Am J Kidney Dis. 2019;73(3):332–43.

    Article  PubMed  Google Scholar 

  46. Farroki F, et al. Association between depression and mortality in patients receiving long-term dialysis: a systematic review and meta-analysis. Am J Kidney Dis. 2014;63(4):623–5.

    Article  Google Scholar 

  47. Steele TE, et al. Quality of life in peritoneal dialysis patients. J Nerv Ment Dis. 1996;184:368–74.

    Article  CAS  PubMed  Google Scholar 

  48. Sensky T, Leger C, Gilmour S. Psychosocial and cognitive factors associated with adherence to dietary and fluid restriction regimens by people on chronic haemodialysis. Psychother Psychosom. 1996;65(1):36–42.

    Article  CAS  PubMed  Google Scholar 

  49. Lew SQ, Piraino B. Quality of life and psychological issues in peritoneal dialysis patients. Semin Dial. 2005;18(2):119–23.

    Article  PubMed  Google Scholar 

  50. Troidle L, et al. Depression and its association with peritonitis in long-term peritoneal dialysis patients. Am J Kidney Dis. 2003;42(2):350–4.

    Article  PubMed  Google Scholar 

  51. Palmer S, et al. Prevalence of depression in chronic kidney disease: systematic review and meta-analysis of observational studies. Kidney Int. 2013;84:174–91.

    Article  Google Scholar 

  52. Jung HY, et al. Depressive symptoms, patient satisfaction, and quality of life over time in automated and continuous ambulatory peritoneal dialysis patients. Medicine (Baltimore). 2016;95(21):e3795.

    Article  Google Scholar 

  53. Wuerth D, et al. Identification and treatment of depression in a cohort of patients maintained on chronic peritoneal dialysis. Am J Kidney Dis. 2001;37(5):1011–7.

    Article  CAS  PubMed  Google Scholar 

  54. Mok MMY, et al. A longitudinal study on the prevalence and risk factors for depression and anxiety, quality of life, and clinical outcomes in incident peritoneal dialysis patients. Perit Dial Int. 2019;39(1):174–82.

    Article  Google Scholar 

  55. Griva K, et al. Predicting technique and patient survival over 12 months in peritoneal dialysis: the role of anxiety and depression. Int Urol Nephrol. 2016;48(5):791–6.

    Article  CAS  PubMed  Google Scholar 

  56. Partridge KA, Robertson N. Body-image disturbance in adult dialysis patients. Disabil Rehabil. 2010;33(6):504–10.

    Article  PubMed  Google Scholar 

  57. Oyekcin DG, et al. Depression, anxiety, body image, sexual functioning, and dyadic adjustment associated with dialysis type in chronic renal failure. Int J Psychiatry Med. 2012;43(3):227–41.

    Article  PubMed  Google Scholar 

  58. Diemont WL, et al. Sexual dysfunction after renal replacement therapy. Am J Kidney Dis. 2000;35:845–54.

    Article  CAS  PubMed  Google Scholar 

  59. Michels WM, et al. Quality of life in automated and continuous ambulatory peritoneal dialysis. Perit Dial Int. 2011;31(2):138–47.

    Article  PubMed  Google Scholar 

  60. Johansson L, Hickson M, Brown EA. Influence of psychosocial factors on the energy and protein intake of older people on dialysis. J Ren Nut. 2013;23(5):348–55.

    Article  Google Scholar 

  61. Johansson L. Nutrition in older adults on peritoneal dialysis. Perit Dial Int. 2015;35(6):655–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  62. Kosmadakis G, et al. Gastrointestinal disorders in peritoneal dialysis patients. Am J Nephrol. 2018;48(5):319–25.

    Article  PubMed  Google Scholar 

  63. Masoumi M, et al. Sleep quality in patients on maintenance hemodialysis and peritoneal dialysis. Int J Prev Med. 2013;4(2):165–72.

    PubMed  PubMed Central  Google Scholar 

  64. Tang SCW, et al. Improvement in sleep apnea during nocturnal peritoneal dialysis is associated with reduced airway congestion and better uremic clearance. Clin Am J Soc Nephrol. 2009;4(2):410–8.

    Article  Google Scholar 

  65. Dowling TC. Prevalence, etiology, and consequences of anemia and clinical and economic benefits of anemia correction in patients with chronic kidney disease: an overview. Am J Health Syst Pharm. 2007;64(13):S3–7.

    Article  PubMed  Google Scholar 

  66. Alexander M, et al. Association of anemia correction with health related quality of life in patients not on dialysis. Curr Med Res Opin. 2007;23(12):2997–3008.

    Article  CAS  PubMed  Google Scholar 

  67. Okpechi IG, Ntithe T, Swanepoel CR. Health-related quality of life in patients on hemodialysis and peritoneal dialysis. Saudi J Kidney Dis Transpl. 2003;24(3):519–26.

    Article  Google Scholar 

  68. Campbell DJ, et al. Patient’s perspectives on the prevention and treatment of peritonitis in peritoneal dialysis: a semi-structured interview study. Perit Dial Int. 2016;36(6):631–9.

    Article  PubMed  PubMed Central  Google Scholar 

  69. Kerschbaum J, Konig P, Rudnicki M. Risk factors associated with peritoneal-dialysis-related peritonitis. Int J Nephrol. 2012;2012:483250.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Park HC, et al. Lower residual renal function is a risk factor for depression and impaired health-related quality of life in korean peritoneal dialysis patients. J Korean Med Sci. 2012;27(1):64–71.

    Article  CAS  PubMed  Google Scholar 

  71. Xhou W, et al. The impact of residual renal function on quality of life in patients with peritoneal dialysis. Clin Nephrol. 2018;90(2):106–12.

    Article  Google Scholar 

  72. Lo WK, et al. Effect of Kt/V on survival and clinical outcome in CAPD patients in a randomized prospective study. Kidney Int. 2003;64(2):649–56.

    Article  PubMed  Google Scholar 

  73. Paniangua R, et al. Health-related quality of life predicts outcomes but is not affected by peritoneal clearance: the ADEMEX trial. Kidney Int. 2005;67(3):1093–104.

    Article  Google Scholar 

  74. Bro S, et al. A prospective, randomized multicenter study comparing APD and CAPD treatment. Perit Dial Int. 1999;19(6):526–3.

    Article  CAS  PubMed  Google Scholar 

  75. Htay H, et al. Biocompatible dialysis fluids for peritoneal dialysis. Cochrane Database Syst Rev. 2018;10:CD007554.

    PubMed  Google Scholar 

  76. Hassan K, et al. Associations of peritoneal glucose load with male sexual dysfunction and depression in peritoneal dialysis patients. Ther Apher Dial. 2018;22(4):380–8.

    Article  CAS  PubMed  Google Scholar 

  77. Guo A, Wolfson M, Holt R. Early quality of life benefits of icodextrin in peritoneal dialysis. Kidney Int Suppl. 2002;81:S72–9.

    Article  Google Scholar 

  78. Chow SK, Wong FK. Health-related quality of life in patients undergoing peritoneal dialysis: effects of a nurse-led case management programme. J Adv Nurs. 2010;66(8):1780–92.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, UK

    Jack Beadle & Edwina A. Brown

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  1. Jack Beadle
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  2. Edwina A. Brown
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Correspondence to Edwina A. Brown .

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Editors and Affiliations

  1. CORE Kidney Health Program, Department of Medicine, Division of Nephrology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

    Anjay Rastogi

  2. University of Illinois at Chicago, College of Medicine, Chicago, IL, USA

    Edgar V. Lerma

  3. Division of Nephrology, University of Toronto, University Health Network/Toronto General Hospital, Toronto, ON, Canada

    Joanne M. Bargman

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Beadle, J., Brown, E.A. (2021). Quality of Life in Peritoneal Dialysis. In: Rastogi, A., Lerma, E.V., Bargman, J.M. (eds) Applied Peritoneal Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-030-70897-9_22

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  • DOI: https://doi.org/10.1007/978-3-030-70897-9_22

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