Abstract
As numerously depicted elsewhere in this book, the clinical problem of well-differentiated nonmuscle-invasive bladder cancer is the markedly high recurrence rate. A valuable tool of the management of these tumors is single immediate instillation, dubbed early instillation, i.e., a single dose of chemotherapy instilled into the bladder immediately after transurethral resection of bladder tumor (TURBT). In this chapter, the rationale and practical considerations of single immediate instillations directly after TURBT are lined out. Single immediate instillation is effective in nonmuscle-invasive bladder cancer of low-risk constellation, i.e., primary, solitary, and small tumors with presumed high-grade differentiation. As agents, mitomycin C, epirubicin, pirarubicin, and gemcitabine have been assessed with largely comparable effects.
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Burger, M. (2021). Single Immediate Intravesical Instillation of Chemotherapy- Rationale and Practical Considerations. In: Kamat, A.M., Black, P.C. (eds) Bladder Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-70646-3_8
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DOI: https://doi.org/10.1007/978-3-030-70646-3_8
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