Abstract
CNS involvement in AML in adults is rare and usually associated with a dismal prognosis. One of the most frequent forms of CNS infiltration is myeloid sarcoma of the dura and subperiosteum, described here.
Keywords
- AML
- Leukaemia
- CNS
- Myeloid sarcomaChloroma
- Dura
- Pachymeninx
This is a preview of subscription content, access via your institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Döhner H, et al. Acute myeloid leukemia. N Engl J Med. 2015;373(12):1136–52. https://doi.org/10.1056/NEJMra1406184.
Bar M, et al. Central nervous system involvement in acute myeloid leukemia patients undergoing hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2015;21(3):546–51. https://doi.org/10.1016/j.bbmt.2014.11.683.
Alakel N, et al. Symptomatic central nervous system involvement in adult patients with acute myeloid leukemia. Cancer Manag Res. 2017;9:97–102. https://doi.org/10.2147/CMAR.S125259.
Patkowska E, et al. Primary and secondary central nervous system involvement in acute myeloid leukemia. J Leuke. 2019;7:257. https://doi.org/10.24105/2329-6917.7.257.
Cheng C-L, et al. Risk factors and clinical outcomes of acute myeloid leukaemia with central nervous system involvement in adults. BMC Cancer. 2015;15:344. https://doi.org/10.1186/s12885-015-1376-9.
Cervantes GM, Cayci Z. Intracranial CNS manifestations of myeloid sarcoma in patients with acute myeloid leukemia: review of the literature and three case reports from the author's institution. J Clin Med. 2015;4(5):1102–12. https://doi.org/10.3390/jcm4051102.
Yang B, et al. Clinicoradiological characteristics, management and prognosis of primary myeloid sarcoma of the central nervous system: a report of four cases. Oncol Lett. 2017;14(3):3825–31. https://doi.org/10.3892/ol.2017.6620.
Audouin J, et al. Myeloid sarcoma: clinical and morphologic criteria useful for diagnosis. Int J Surg Pathol. 2003;11(4):271–82. https://doi.org/10.1177/106689690301100404.
Singh A, et al. Unravelling chloroma: review of imaging findings. Br J Radiol. 2017;90(1075):20160710. https://doi.org/10.1259/bjr.20160710.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Vavro, H. (2021). Pachymeningial Involvement in Acute Myeloid Leukaemia (AML). In: Neuroradiology - Images vs Symptoms. Springer, Cham. https://doi.org/10.1007/978-3-030-69213-1_19
Download citation
DOI: https://doi.org/10.1007/978-3-030-69213-1_19
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-69212-4
Online ISBN: 978-3-030-69213-1
eBook Packages: MedicineMedicine (R0)