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Protein Translocation into the Nucleus during Leukemia Cell Differentiation

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Epigenetics and Proteomics of Leukemia

Abstract

Protein moves between cell compartments as cells develop and functioning. This is closely related to signal transmission from cell surface into the nucleus. In the Chap. 7 we have described a method for the study of protein translocation from the cytoplasm into the nucleus. And we provided a method for estimating where protein phosphorylation occurs. The identified tyrosine phosphorylated proteins translocated into the nucleus of leukemic cells during granulocytic differentiation are defined.

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Navakauskienė, R., Navakauskas, D., Borutinskaitė, V., Matuzevičius, D. (2021). Protein Translocation into the Nucleus during Leukemia Cell Differentiation. In: Epigenetics and Proteomics of Leukemia. Springer, Cham. https://doi.org/10.1007/978-3-030-68708-3_7

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