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Gross Pathology in Schizophrenia

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The Neuropathology of Schizophrenia

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Abstract

The difficulties in identifying brain pathology typical of schizophrenia are present in large-scale changes of the brain as much as in finer neuropathology, but there are several pathological findings which have become commonplace enough to be accepted as general characteristics of the disorder. Enlarged ventricles are possibly the most consistent in the illness, with imaging sciences suggesting the schizophrenic brain is smoother and lighter by a few percent. The familiar brain torque observed in healthy brains is often decreased or lost in schizophrenia, producing several theories as to the developmental cause. Whatever to complexities found in the illness in specific regions of interest, it seems that the development of schizophrenia leaves its mark global on pathology.

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  1. Francis Fraser Clinic, Hammersmith Hospital, London, UK

    Matthew Williams

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Williams, M. (2021). Gross Pathology in Schizophrenia. In: Williams, M. (eds) The Neuropathology of Schizophrenia. Springer, Cham. https://doi.org/10.1007/978-3-030-68308-5_3

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