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Posterior Reversible Encephalopathy Syndrome (PRES) and Meningo-Encephalitis in COVID

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Neuroimaging of Covid-19. First Insights based on Clinical Cases

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Abstract

Neurological symptoms described in COVID-19 infected patients can also occur in a more inflammatory related setting as in case of posterior reversible encephalopathy syndrome (PRES) that can be associated with SARS-CoV2 infection due to the massive cytokine storm, damage to endothelium and vasogenic oedema. At brain imaging, quite symmetric bilateral focal or confluent vasogenic oedema with posterior parietal and occipital lobe involvement are found. In severe cases like in COVID-setting, PRES can be complicated by ischemia or haemorrhage: we then describe in the atlas two cases of classic and complicated COVID-related PRES.

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Acknowledgements

Cases 1 and 2 of Sect. 4.1 and Case 2 of Sect. 4.2 courtesy of:

  • E. D’Adda, MD; M.E. Fruguglietti, MD; Neurologist Stroke Unit Cerebrovascular Dept; ASST Crema Hospital

  • M. Borghetti MD, G. Benelli MD; Radiology Unit, Cerebrovascular Dept; ASST Crema Hospital

  • G. Merli MD, G. Lupi MD, Department of Anesthesia and Critical Care Medicine, ASST Crema Hospital

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  1. Neuroradiology Department, Papa Giovanni XXIII Hospital, Bergamo, Italy

    Ornella Manara, Giulio Pezzetti & Simonetta Gerevini

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    Simonetta Gerevini M.D.

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Manara, O., Pezzetti, G., Gerevini, S. (2021). Posterior Reversible Encephalopathy Syndrome (PRES) and Meningo-Encephalitis in COVID. In: Gerevini M.D., S. (eds) Neuroimaging of Covid-19. First Insights based on Clinical Cases. Springer, Cham. https://doi.org/10.1007/978-3-030-67521-9_4

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