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Absorbable Wire Radiopacity: Influence of Composition and Size on X-ray Visibility

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Magnesium Technology 2021

Abstract

Imaging systems employing X-rays (such a 2D projectional radiography, computed tomography, and fluoroscopy) are widely used in medicine to aid in surgical planning, intervention, and follow up. Visualization of medical devices using these techniques relies on differences in x-ray absorption between the medical device and the surrounding tissue. The amount of absorption of a given device is largely a function of its cross-sectional dimensions, density, and atomic properties. Consequently, imaging of relatively small devices, like stents, made of a low-density material, like magnesium, can be very challenging. The aim of this study is to quantify the relative radiopacities of key absorbable metal alloy systems, determine the influence of magnesium alloy composition on radiopacity, and estimate the diameters at which wires are no longer visible under typical clinical conditions. This is accomplished by producing wires from five different magnesium alloys, a zinc alloy, and an iron alloy, in sizes ranging from 0.2 to 1.0 mm diameter, and imaging on a clinical x-ray system.

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References

  1. J. Rosch, F. Keller and J. Kaufman, “The Birth, Early Years, and Future of Interventional Radiology,” Journal of Vascular Interventional Radiology, vol. 14, pp. 841–853, 2003.

    Article  Google Scholar 

  2. H. Chen, M. Rogalski and J. Anker, “Advances in functional X-ray imaging techniques and contrast agents,” Physical Chemistry Chemical Physics, no. 39, 2012

    Google Scholar 

  3. S. A. M. Tofail, J. M. Carlson, A. A. Gandhi, J. Butler, P. Tiernan and L. O’Donoghue, “Nickel-titanium-rare earth alloy and method of processing the alloy”. USA Patent 8,440,031 B2, 2013

    Google Scholar 

  4. X.-m. Li and e. al, “Evaluation of peripheral artery stent with 64-slice multi-detector row CT angiography: prospective comparison with digital subtraction angiography,” European Journal of Radiology, vol. 75, no. 1, pp. 98–103, 2010

    Google Scholar 

  5. A. Kastrati, J. Mehilli and et al, “Intracoronary Stenting and Angiographic Results,” Circulation, vol. 103, pp. 2816–2821, 2001.

    Google Scholar 

  6. R. Noad, C. Hanratty and S. Walsh, “Clinical Impact of Stent Design,” Interventional Cardiology Review, vol. 9, no. 2, pp. 89–93, 2014.

    Article  Google Scholar 

  7. G. Rajah, S. Narayanan and L. Rangel-Castilla, “Update on flow diverters for the endovascular,” Neurosurgical Focus, vol. 42, no. 6, 2017.

    Google Scholar 

  8. P. Maier, A. Steinacker, B. Clausius and N. Hort, “Influence of Solution Heat Treatment on the Microstructure Hardness and Stress Corrosion Behavior of Extruded Resoloy(R),” JOM, pp. 1870–1879, 2020

    Google Scholar 

  9. A. Griebel, “An in vitro and in vivo characterization of fine WE43B magnesium wire with varied thermomechanical processing conditions,” Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2017

    Google Scholar 

  10. M. Stekker, N. Hort, F. Feyerabend, E. Hoffmann, M. Hoffmann and R. Horres, “Resorbable stents which contain a magnesium alloy”. USA Patent 9522219 B2, 2016

    Google Scholar 

  11. Y. Zheng, X. Gu and F. Witte, “Biodegradable Metals,” Materials Science and Engineering R, vol. 77, pp. 1–34, 2015

    Article  Google Scholar 

  12. M. Sikora-Jasinska, “Fabrication, mechanical properties and in vitro degradation behavior of newly developed Zn-Ag alloys for degradable implant applications,” Materials Science and Engineering: C, pp. 1170–1181, 2017

    Google Scholar 

  13. J. Schaffer, “Cold drawn bioabsorbable ferrous and ferrous composite wires: An evaluation of in vitro vascular cytocompatibility,” Acta Biomaterialia, pp. 8574–8584, 2013

    Google Scholar 

  14. Sonnow, “Biodegradable magnesium Herbert screw – image quality and artifacts with radiography, CT and MRI,” BMC Medical Imaging, 2017

    Google Scholar 

  15. J. Espiritu, J. Seitz and M. Meier, “The performance of Mg-based implants in MRI: a systematic review,” in Updates in Bioabsorbable Metals, Virtual, 2020

    Google Scholar 

  16. ASTM International, F640: Standard Test Methods for Determining Radiopacity for Medical Use, 2012

    Google Scholar 

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Correspondence to Adam J. Griebel .

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© 2021 The Minerals, Metals & Materials Society

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Griebel, A.J., Ehle, A.L., Schaffer, J.E. (2021). Absorbable Wire Radiopacity: Influence of Composition and Size on X-ray Visibility. In: Miller, V.M., Maier, P., Jordon, J.B., Neelameggham, N.R. (eds) Magnesium Technology 2021. The Minerals, Metals & Materials Series. Springer, Cham. https://doi.org/10.1007/978-3-030-65528-0_17

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