Abstract
Thermal ablative techniques have been used in kidney tumour treatments; these treatments use electromagnetic energy to increase the temperature of the target tissue in order to destroy it. Dielectric and thermal properties influence the deposition of electromagnetic energy and the heat distribution into the tissue, respectively. Accurate knowledge of dielectric and thermal properties permits accurate modelling of the therapeutic results. Extensive research has been conducted on dielectric property characterisation of tissue, while significantly less data are available in literature on thermal property characterisation. The aim of this study is to experimentally investigate the kidney thermal properties in ex vivo ovine models (n = 4) in a temperature range from room to ablative temperatures (95–96 °C). Results show changes in thermal properties at temperatures approaching the water transition to gas, i.e. above 95 °C.
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References
Iezzi, R., et al.: Radiofrequency thermal ablation of renal graft neoplasms: a literature review. Transp. Rev. 33(3), 161–165 (2019)
Raman, J.D., Jafri, S.M., Qi, D.: Kidney function outcomes following thermal ablation of small renal masses. World J. Nephrol. 5(3), 283 (2016)
Brace, C.L.: Microwave tissue ablation: biophysics, technology, and applications. Critical Rev. Biomed. Eng. 38(1), 65–78 (2010)
Rossmann, C., Haemmerich, D.: Review of temperature dependence of thermal properties, dielectric properties, and perfusion of biological tissues at hyperthermic and ablation temperatures. Critical Rev. Biomed. Eng. 42(6), 467–492 (2014)
Sebek, J., Albin, N., Bortel, R., Natarajan, B., Prakash, P.: Sensitivity of microwave ablation models to tissue biophysical properties: a first step toward probabilistic modeling and treatment planning. Med. Phys. 43(5), 2649–2661 (2016)
Lopresto, V., Pinto, R., Farina, L., Cavagnaro, M.: Microwave thermal ablation: effects of tissue properties variations on predictive models for treatment planning. Med. Eng. Phys. 46(1), 63–70 (2017)
Singh, S., Repaka, R., Al-Jumaily, A.: Sensitivity analysis of critical parameters affecting the efficacy of microwave ablation using Taguchi method. Int. J. RF Microwave Comput.-Aided Eng. 29(4), 1–12 (2019)
Lopresto, V., Pinto, R., Farina, L., Cavagnaro, M.: Treatment planning in microwave thermal ablation: clinical gaps and recent research advances. Int. J. Hyperthermia 33(1), 83–100 (2017)
Porter, E., et al.: Minimum information for dielectric measurements of biological tissues (MINDER): a framework for repeatable and reusable data. Int. J. RF Microwave Comput.-Aided Eng. 28(3), 1–27 (2018)
Ruvio, G., et al.: Comparison of coaxial open-ended probe based dielectric measurements on ex-vivo thermally ablated liver tissue. In: 13th European Conference on Antennas and Propagation (EuCAP), pp. 1–4 (2019)
Lopresto, V., Argentieri, A., Pinto, R., Cavagnaro, M.: Temperature dependence of thermal properties of ex vivo liver tissue up to ablative temperatures. Phys. Med. Biol. 64, 1–13 (2019)
Guntur, S.R., Il Lee, K., Paeng, D.-G., Coleman, A.J., Choi, M.J.: Temperature-dependent thermal properties of ex vivo liver undergoing thermal ablation. Ultrasound Med. Biol. 39(10), 1771–84 (2013)
Bhattacharya, A., Mahajan, R.L.: Temperature dependence of thermal conductivity of biological tissues. Physiol. Measur. 24(3), 769–783 (2003)
Bhavaraju, N.C., Valvano, J.W.: Thermophysical properties of swine myocardium. Int. J. Thermophys. 20(2), 665–676 (1999)
Haemmerich, D., Dos Santos, I., Schutt, D.J., Webster, J.G., Mahvi, D.M.: In vitro measurements of temperature-dependent specific heat of liver tissue. Med. Eng. Phys. 28(2), 194–197 (2006)
Valvano, J.W., Cochran, J.R., Diller, K.R.: Thermal conductivity and diffusivity of biomaterials measured with self-heated thermistors. Int. J. Thermophys. 6(3), 301–311 (1985)
Silva, N.P., Bottiglieri, A., Conceição, R.C., O’Halloran, M., Farina, L.: Thermal properties of ex vivo biological tissue at room and body temperature. In: 14th European Conference on Antennas and Propagation (EuCAP), pp. 1–5 (2020)
Silva, N.P., Bottiglieri, A., Conceição, R.C., O’Halloran, M., Farina, L.: Characterisation of ex vivo liver thermal properties for electromagnetic-based hyperthermic therapies. Sensors 20(10), 1–14 (2020)
METER Group Inc., TEMPOS. Pullman, WA, USA (2018)
Acknowledgments
The research leading to these results has received funding from the European Research Council under the European Horizon-2020 Programme (H2020)/ERC grant agreement n.637780. This publication has emanated from research conducted with the financial support of Science Foundation Ireland (SFI) and is co-funded under the European Regional Development Fund under Grant Number 13/RC/2073. This project has received funding from the European Union Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement n.713690. This work has been developed in the framework of COST Action CA17115 “MyWAVE”.
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Silva, N.P., Bottiglieri, A., Porter, E., O’Halloran, M., Farina, L. (2021). Evaluation of Thermal Properties of Ex Vivo Kidney up to Ablative Temperatures. In: Jarm, T., Cvetkoska, A., Mahnič-Kalamiza, S., Miklavcic, D. (eds) 8th European Medical and Biological Engineering Conference. EMBEC 2020. IFMBE Proceedings, vol 80. Springer, Cham. https://doi.org/10.1007/978-3-030-64610-3_61
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