Skip to main content

Glioblastoma

  • Chapter
  • First Online:
Intracranial and Spinal Radiotherapy

Part of the book series: Practical Guides in Radiation Oncology ((PGRO))

  • 682 Accesses

Abstract

Radiation therapy has been a cornerstone of treatment for patients with glioblastoma for several decades. As imaging and dosimetric advances have occurred over the years, further refinement in targeting of the resection bed and residual tumor cells has occurred. This chapter outlines basic principles and clinical pearls for simulation, contouring, and planning radiation therapy for patients with glioblastoma.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Further Reading

  • Cabrera AR, Kirkpatrick JP, Fiveash JB, Shih HA, Koay EJ, Lutz S, Petit J, Chao ST, Brown PD, Vogelbaum M, Reardon DA, Chakravarti A, Wen PY, Chang E (2016) Radiation therapy for glioblastoma: executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline. Pract Radiat Oncol 6(4):217–225

    Article  Google Scholar 

  • Gebhardt BJ, Dobelbower MC, Ennis WH, Bag AK, Markert JM, Fiveash JB (2014) Patterns of failure for glioblastoma multiforme following limited-margin radiation and concurrent temozolomide. Radiat Oncol 9:130

    Article  Google Scholar 

  • Kruser TJ, Bosch WR, Badiyan SN, Bovi JA, Ghia AJ, Kim MM, Solanki AA, Sachdev S, Tsien C, Wang TJC, Mehta MP, McMullen KP (2019) NRG brain tumor specialists consensus guidelines for glioblastoma contouring. J Neuro-Oncol 143(1):157–166

    Article  Google Scholar 

  • McDonald MW, Shu HK, Curran WJ Jr, Crocker IR (2011) Pattern of failure after limited margin radiotherapy and temozolomide for glioblastoma. Int J Radiat Oncol Biol Phys 79(1):130–136

    Article  CAS  Google Scholar 

  • Niyazi M, Brada M, Chalmers AJ, Combs SE, Erridge SC, Fiorentino A, Grosu AL, Lagerwaard FJ, Minniti G, Mirimanoff RO, Ricardi U, Short SC, Weber DC, Belka C (2016) ESTRO-ACROP guideline “target delineation of glioblastomas”. Radiother Oncol 118(1):35–42

    Article  Google Scholar 

  • Perry JR, Laperriere N, O’Callaghan CJ, Brandes AA, Menten J, Phillips C, Fay M, Nishikawa R, Cairncross JG, Roa W, Osoba D, Rossiter JP, Sahgal A, Hirte H, Laigle-Donadey F, Franceschi E, Chinot O, Golfinopoulos V, Fariselli L, Wick A, Feuvret L, Back M, Tills M, Winch C, Baumert BG, Wick W, Ding K, Mason WP, Trial Investigators (2017) Short-course radiation plus temozolomide in elderly patients with glioblastoma. N Engl J Med 376(11):1027–1037

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to John B. Fiveash .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2021 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Fiveash, J.B., Dulaney, C. (2021). Glioblastoma. In: Halasz, L.M., Lo, S.S., Chang, E.L., Sahgal, A. (eds) Intracranial and Spinal Radiotherapy . Practical Guides in Radiation Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-64508-3_15

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-64508-3_15

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-64507-6

  • Online ISBN: 978-3-030-64508-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics