Abstract
Circulating tumor cells (CTCs) are the main reasons for metastasize and primary tumors, and they have an ability to be cancer markers to monitor the disease progression. The progression of the disease has conventionally been designated by imaging the tumor sizes, hounding the standards of specific proteins found in human serum, etc. Most of these strategies are restricted by their certainty and repeatability, for example, traditionally they can be used to identify the amendments of the tumor sizes CT scans, without providing knowledge-related to the biology of the tumor. Therefore, the treatment with these strategies could be inefficient. So, it is important to have more advanced devices that provide accurate prognostic factors for each patient. This chapter presents two main fields, the first one is about nanomaterial-assisted biosensor implementations with a direct measurement perspective and the second one with microfluidic platforms for the detection and diagnosis of CTCs with emphasis on the studies focused on the types of nanomaterials and signal transduction mechanisms.
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Brimo, N., Serdaroğlu, D.Ç. (2021). Emerging Role of Nanomaterial-Assisted Biosensors for Circulating Tumor Cell Detection. In: Saglam, N., Korkusuz, F., Prasad, R. (eds) Nanotechnology Applications in Health and Environmental Sciences. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-64410-9_9
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