Abstract
The immune system is the primary defense mechanism to protect the body from harmful environment and diseases such as infectious diseases and cancer. Therefore, it is very important that the immune system must work very effectively and strongly. The recent treatment methods developed for modulation of the immune system in an effective defense against diseases include many products of biotechnology. In fact, biotechnological approaches for the new generation immunotherapies are becoming quite innovative novel era. In this chapter, biotechnology products of vaccines and therapeutic monoclonal antibodies, and their applications will be discussed.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Ada G (1997) Overview of vaccines. Mol Biotechnol 8:123–134
Almagro JC, Pedraza-Escalona M, Arrieta HI, Pérez-Tapia SM (2019) Phage display libraries for antibody therapeutic discovery and development. Antibodies (Basel) 8(3). pii: E44
Bagriacik EU (2017) Antigen presenting cell therapies: dendritic cell-based tumor vaccines. Turk Klinikleri J Med Oncol Spec Top 10(2):206–210
Barrett ADT (2017) Yellow fever live attenuated vaccine: a very successful live attenuated vaccine but still we have problems controlling the disease. Vaccine 35:5951–5955
Bartlett BL, Pellicane AJ, Tyring SK (2009) Vaccine immunology. Dermatol Ther 22(2):104–109
Betáková T, SvetlÃková D, GocnÃk M (2013) Overview of measles and mumps vaccine: origin, present, and future of vaccine production. Acta Virol 57:91–96
Bizzini B (1979) Tetanus toxin. Microbiol Rev 43:224–240
Brüggemann M, Osborn MJ, Ma B, Hayre J, Avis S, Lundstrom B, Buelow R (2015) Human antibody production in transgenic animals. Arch Immunol Ther Exp 63:101–108
Burke RM, Tate JE, Kirkwood CD, Steele AD, Parashar UD (2019) Current and new rotavirus vaccines. Curr Opin Infect Dis 32:435–444
Carter H, Campbell H (1993) Rational use of measles, mumps and rubella (MMR) vaccine. Drugs 45:677–683
Chung Y-J, Jung M-Y, Lee J-A, Kim T-Y, Choe Y-K, Kim I-H (2016) Tetanus toxin production from Clostridium tetani, using a casein-based medium in a single-use bioreactor. Biotechnol Bioprocess Eng 21:531–536
Coursaget P, Bringer L, Sarr G, Bourdil C, Fritzell B, Blondeau C, Yvonnet B, Chiron JP, Jeannée E, Guindo S et al (1992) Comparative immunogenicity in children of mammalian cell-derived recombinant hepatitis B vaccine and plasma-derived hepatitis B vaccine. Vaccine 10:379–382
Dahl O, Brydøy M (2018) The pioneers behind immune checkpoint blockers awarded the Nobel Prize in physiology or medicine 2018. Acta Oncol 58:1–8
Deering RP, Kommareddy S, Ulmer JB, Brito LA, Geall AJ (2014) Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines. Expert Opin Drug Deliv 11:885–899
Dorner F, Barrett PN (1999) Vaccine technology: looking to the future. Ann Med 31:51–60
Feldman C, Anderson R (2014) Review: current and new generation pneumococcal vaccines. J Infect 69(4):309–325
Gatti-Mays ME, Redman JM, Collins JM, Bilusic M (2017) Cancer vaccines: enhanced immunogenic modulation through therapeutic combinations. Hum Vaccin Immunother 13:2561–2574
Glyn I, Glyn J (2004) The life and death of smallpox. Cambridge University Press, New York, p 269. ISBN: 0 521 84542 4
Grilo AL, Mantalaris A (2019) The increasingly human and profitable monoclonal antibody market. Trends Biotechnol 37:9–16
Hannoun C (2013) The evolving history of influenza viruses and influenza vaccines. Expert Rev Vaccines 12:1085–1094
Hawken J, Troy SB (2012) Adjuvants and inactivated polio vaccine: a systematic review. Vaccine 30:6971–6979
Hicks DJ, Fooks AR, Johnson N (2012) Developments in rabies vaccines. Clin Exp Immunol 169:199–204
Kapil P, Merkel TJ (2019) Pertussis vaccines and protective immunity. Curr Opin Immunol 59:72–78
Knuf M, Faber J, Barth I, Habermehl P (2008) A combination vaccine against measles, mumps, rubella and varicella. Drugs Today (Barc) 44:279–292
Leclerc C (2003) New approaches in vaccine development. Comp Immunol Microbiol Infect Dis 26:329–341
Maynard J, Georgiou G (2000) Antibody engineering. Annu Rev Biomed Eng 2:339–376
Nothdurft HD (2008) Hepatitis A vaccines. Expert Rev Vaccines 7:535–545
Petrosky E, Bocchini JA Jr, Hariri S, Chesson H, Curtis CR, Saraiya M et al (2015) Use of 9-valent human papillomavirus (HPV) vaccine: updated HPV vaccination recommendations of the advisory committee on immunization practices. MMWR Morb Mortal Wkly Rep 64:300–304
Rapley R (1995) The biotechnology and applications of antibody engineering. Mol Biotechnol 3(2):139–154
Relyveld EH (1980) Current developments in production and testing of tetanus and diphtheria vaccines. Prog Clin Biol Res 47:51–76
Rossetto O, Scorzeto M, Megighian A, Montecucco C (2013) Tetanus neurotoxin. Toxicon 66:59–63
Shim H (2016) Therapeutic antibodies by phage display. Curr Pharm Des 22:6538–6559
Thomas S, Prendergast GC (2016) Cancer vaccines: a brief overview. Methods Mol Biol 1403:755–761
Vitek CR, Wharton M (2008) Diphtheria toxoid. In: Plotkin SA, Orenstein WA, Offit PA (eds) Vaccines. Saunders/Elsevier, Philadelphia, pp 139–156
Wang M, Jiang S, Wang Y (2016) Recent advances in the production of recombinant subunit vaccines in Pichia pastoris. Bioengineered 7:155–165
Wang S, Tafalla M, Hanssens L, Dolhain J (2017) A review of Haemophilus influenzae disease in Europe from 2000-2014: challenges, successes and the contribution of hexavalent combination vaccines. Expert Rev Vaccines 16:1095–1105
Warren-Gash C, Forbes H, Breuer J (2017) Varicella and herpes zoster vaccine development: lessons learned. Expert Rev Vaccines 16:1191–1201
Wirz M, Gentili G, Collotti C (1990) Tetanus vaccine: present status. Adv Biotechnol Process 13:35–55
Zughaier SM (2017) Analysis of novel meningococcal vaccine formulations. Hum Vaccin Immunother 13:1728–1732
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Bagriacik, E.U. (2021). Biotechnological Approaches in Maintenance of a Healthy Immune System for Protection Against Diseases. In: Saglam, N., Korkusuz, F., Prasad, R. (eds) Nanotechnology Applications in Health and Environmental Sciences. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-64410-9_15
Download citation
DOI: https://doi.org/10.1007/978-3-030-64410-9_15
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-64409-3
Online ISBN: 978-3-030-64410-9
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)