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Pathophysiology of Types of Pediatric and Adolescent Diabetes

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Diabetes in Children and Adolescents

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

In this chapter, we will describe the many and varied types of diabetes that can affect youth. We will also discuss the synthesis of insulin and mechanisms regulating β-cell secretion in non-diabetic individuals, as well as insulin-mediated glucose clearance. The development of hyperglycemia and pathogenesis of ketogenesis in type 1 diabetes will be presented, as well as differences between type 1 and type 2 diabetes.

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Authors and Affiliations

  1. Yale-New Haven Children’s Hospital, Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA

    Stephan Siebel & Pamela Hu

  2. Yale University School of Medicine, Cellular & Molecular Physiology and Internal Medicine (Endocrinology), New Haven, CT, USA

    Rachel Perry

Authors
  1. Stephan Siebel
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  2. Pamela Hu
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  3. Rachel Perry
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Corresponding author

Correspondence to Stephan Siebel .

Editor information

Editors and Affiliations

  1. Yale-New Haven Children’s Hospital, Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA

    William V. Tamborlane

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Siebel, S., Hu, P., Perry, R. (2021). Pathophysiology of Types of Pediatric and Adolescent Diabetes. In: Tamborlane, W.V. (eds) Diabetes in Children and Adolescents. Contemporary Endocrinology. Humana, Cham. https://doi.org/10.1007/978-3-030-64133-7_2

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  • DOI: https://doi.org/10.1007/978-3-030-64133-7_2

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  • Publisher Name: Humana, Cham

  • Print ISBN: 978-3-030-64132-0

  • Online ISBN: 978-3-030-64133-7

  • eBook Packages: MedicineMedicine (R0)

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