What you will learn
The content of the following chapter briefly describes the basics of biological genetic information and their function in living organisms. You will gain principle knowledge on DNA and RNA and understand the differences of analyzing these by sequencing templates. Next generation sequencing technologies can be used to sequence DNA or RNA, respectively, answering the research or clinical question you have. Different sequencing approaches thus lead to different readouts.
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Acknowledgements
We are grateful to Dr. Ines Böhme (Institute of Biochemistry (Emil-Fischer Center), Friedrich–Alexander (University Erlangen–Nürnberg, Erlangen, Germany) for critically reading this text and correcting our mistakes.
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Bosserhoff, A., Kappelmann-Fenzl, M. (2021). Next Generation Sequencing (NGS): What Can Be Sequenced?. In: Kappelmann-Fenzl, M. (eds) Next Generation Sequencing and Data Analysis. Learning Materials in Biosciences. Springer, Cham. https://doi.org/10.1007/978-3-030-62490-3_1
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DOI: https://doi.org/10.1007/978-3-030-62490-3_1
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