Skip to main content

Semi-supervised Instance Segmentation with a Learned Shape Prior

Part of the Lecture Notes in Computer Science book series (LNIP,volume 12446)

Abstract

To date, most instance segmentation approaches are based on supervised learning that requires a considerable amount of annotated object contours as training ground truth. Here, we propose a framework that searches for the target object based on a shape prior. The shape prior model is learned with a variational autoencoder that requires only a very limited amount of training data: In our experiments, a few dozens of object shape patches from the target dataset, as well as purely synthetic shapes, were sufficient to achieve results en par with supervised methods with full access to training data on two out of three cell segmentation datasets. Our method with a synthetic shape prior was superior to pre-trained supervised models with access to limited domain-specific training data on all three datasets. Since the learning of prior models requires shape patches, whether real or synthetic data, we call this framework semi-supervised learning. The code is available to the public (https://github.com/looooongChen/shape_prior_seg).

Keywords

  • Semi-supervised
  • Instance segmentation
  • Shape prior
  • Variational autoencoder
  • Edge loss

This work was supported by the Deutsche Forschungsgemeinschaft (Research Training Group 2416 MultiSenses-MultiScales).

This is a preview of subscription content, access via your institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Notes

  1. 1.

    https://data.broadinstitute.org/bbbc.

  2. 2.

    https://cocodataset.org/.

  3. 3.

    https://www.kaggle.com/c/data-science-bowl-2018.

References

  1. Ulman, V., et al.: An objective comparison of cell-tracking algorithms. Nat. Methods 14, 1141–1152 (2017)

    CrossRef  Google Scholar 

  2. He, K., Gkioxari, G., Dollár, P., Girshick, R.: Mask R-CNN. In: ICCV 2017, pp. 2980–2988 (2017)

    Google Scholar 

  3. Schmidt, U., Weigert, M., Broaddus, C., Myers, G.: Cell detection with star-convex polygons. In: Frangi, A., Schnabel, J., Davatzikos, C., Alberola-López, C., Fichtinger, G. (eds.) MICCAI 2018. LNCS, vol. 11071, pp. 265–273. Springer, Cham (2018). https://doi.org/10.1007/978-3-030-00934-2_30

    CrossRef  Google Scholar 

  4. Chen, L., Strauch, M., Merhof, D.: Instance segmentation of biomedical images with an object-aware embedding learned with local constraints. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11764, pp. 451–459. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32239-7_50

    CrossRef  Google Scholar 

  5. Oktay, O., et al.: Anatomically constrained neural networks (ACNNs): application to cardiac image enhancement and segmentation. IEEE Trans. Med. Imaging 37(2), 384–395 (2018)

    CrossRef  Google Scholar 

  6. Larrazabal, A.J., Martinez, C., Ferrante, E.: Anatomical priors for image segmentation via post-processing with denoising autoencoders. In: Shen, D., et al. (eds.) MICCAI 2019. LNCS, vol. 11769, pp. 585–593. Springer, Cham (2019). https://doi.org/10.1007/978-3-030-32226-7_65

    CrossRef  Google Scholar 

  7. Dalca, A.V., Guttag, J., Sabuncu, M.R.: Anatomical priors in convolutional networks for unsupervised biomedical segmentation. In: CVPR 2018, pp. 9290–9299 (2018)

    Google Scholar 

  8. Crawford, E., Pineau, J.: Spatially invariant unsupervised object detection with convolutional neural networks. In: AAAI 2019, pp. 3412–3420 (2019)

    Google Scholar 

  9. Jaderberg, M., Simonyan, K., Zisserman, A., Kavukcuoglu, K.: Spatial transformer networks. In: NIPS 2015, pp. 2017–2025 (2015)

    Google Scholar 

  10. Kingma, D.P., Welling, M.: Auto-encoding variational Bayes. In: ICLR 2014 (2014)

    Google Scholar 

  11. Simard, P.Y., Steinkraus, D., Platt, J.C.: Best practices for convolutional neural networks applied to visual document analysis. In: Proceedings of the Seventh International Conference on Document Analysis and Recognition, p. 958. IEEE (2003)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Long Chen .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and Permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Chen, L., Zhang, W., Wu, Y., Strauch, M., Merhof, D. (2020). Semi-supervised Instance Segmentation with a Learned Shape Prior. In: Cardoso, J., et al. Interpretable and Annotation-Efficient Learning for Medical Image Computing. IMIMIC MIL3ID LABELS 2020 2020 2020. Lecture Notes in Computer Science(), vol 12446. Springer, Cham. https://doi.org/10.1007/978-3-030-61166-8_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-61166-8_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-61165-1

  • Online ISBN: 978-3-030-61166-8

  • eBook Packages: Computer ScienceComputer Science (R0)