Abstract
Cleft lip and palate (CLP) is the most common congenital craniofacial anomaly and constitutes about 13% of all congenital anomalies. The CLP has wide range presentations and severity. Understanding the embryology and anatomy of the deformity is the key point for the treatment. This chapter aims to present the basis of anatomical distortions and highlight some important variations and discuss about its classification.
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References
Allori AC, Mulliken JB, Meara JG, Shusterman S, Marcus JR. Classification of cleft lip/palate: then and now. Cleft Palate Craniofac J. 2017;54(2):175–88. https://doi.org/10.1597/14-080.
Alonso N, Amaral CER d. Cleft lip and palate treatment: a comprehensive guide. Cham: Springer; 2018.
Batra P, Duggal R, Parkash H. Genetics of cleft lip and palate revisited. J Clin Pediatr Dent. 2003;27(4):311–20.
Brito LA, Meira JGC, Kobayashi GS, Passos-Bueno MR. Genetics and management of the patient with orofacial cleft. Plast Surg Int. 2012;2012:782821. https://doi.org/10.1155/2012/782821.
Campbell A, Restrepo C, eds. Essentials of Cleft Surgery. Cartagena: Global Surgical Arts; 2017.
Campbell A, Restrepo C, Park E, et al. Influence of severity on aesthetic outcomes of unilateral cleft lip repair in 1,823 patients. Plast Recon Surg Global Open. 2019;7:e2083.
Fogh-Andersen, P. Epidemiology and etiology of clefts. Birth Defects Orig Artic Ser. 1971;7(7):50–53.
Kernahan DA. The striped Y—a symbolic classification for cleft lip and palate. Plast Reconstr Surg. 1971;47:469–470.
Leslie EJ, Marazita ML. Genetics of cleft lip and cleft palate. Am J Med Genet C Semin Med Genet. 2013;163c(4):246–58. https://doi.org/10.1002/ajmg.c.31381.
Mossey P, Little J. Addressing the challenges of cleft lip and palate research in India. Indian J Plast Surg. 2009;42 Suppl:S9–s18. https://doi.org/10.4103/0970-0358.57182.
Mossey PA, Little J, Munger RG, Dixon MJ, Shaw WC. Cleft lip and palate. Lancet. 2009;374(9703):1773–85. https://doi.org/10.1016/s0140-6736(09)60695-4.
Mossey PA, Modell B. Epidemiology of oral clefts 2012: an international perspective. Front Oral Biol. 2012;16:1–18. https://doi.org/10.1159/000337464.
Rossell-Perry P, Nano EC, Gavino-Gutierrez AM. Association between palatal index and cleft palate repair outcomes in patients with complete unilateral cleft lip and palate. JAMA Facial Plast Surg. 2014;16(3):206–10.
Smarius B, Loozen C, Manten W, Bekker M, Pistorius L, Breugem C. Accurate diagnosis of prenatal cleft lip/palate by understanding the embryology. World J Methodol. 2017;7(3):93–100.
Sperber GH. In: Sperber SM, Guttmann GD, Sperber GH, editors. Craniofacial embryogenetics and development. 2nd ed. Shelton: People’s Medical Pub. House USA; 2010.
Spina V. A proposed modification for the classification of cleft lip and cleft palate. Cleft Palate J. 1973;10:251–2.
World health Organization (WHO), I. C. o. B. D., European Surveillance of Congenital Anomalies (EUROCAT). World atlas of birth defects. 2nd ed. Geneva: World Health Organization; 2003.
Wu RT, Peck CJ, Shultz BN, Travieso R, Steinbacher DM. Racial disparities in cleft palate repair. Plast Reconstr Surg. 2019;143(6):1738–45. https://doi.org/10.1097/prs.0000000000005650.
Yao CA, Imahiyerobo T, Swanson J, Auslander A, De Cardenas D, Figueiredo JC, McCullough M, Costa M, Vanderburg R, Magee WP. The smile index: part 1. A large-scale study of phenotypic norms for preoperative and postoperative unilateral cleft lip. Plast Reconstr Surg. 2018;141(1):137–46.
Zhang Z, Stein M, Mercer N, Malic C. Post-operative outcomes after cleft palate repair in syndromic and non-syndromic children: a systematic review protocol. Syst Rev. 2017;6:1–7.
Zhao J, Zhang B, Yang S, Mei H, Qian Z, Liang S, . . . Du Y. Maternal exposure to ambient air pollutant and risk of oral clefts in Wuhan, China. Environ Pollut. 2018;238:624–630. https://doi.org/10.1016/j.envpol.2018.03.053.
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da Silva Freitas, R., Nasser, I.J.G., Zimmerman, C., Lupion, F.G. (2021). Patterns, Anatomy, and Classification of Clefts. In: Swanson, J.W. (eds) Global Cleft Care in Low-Resource Settings. Springer, Cham. https://doi.org/10.1007/978-3-030-59105-2_5
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DOI: https://doi.org/10.1007/978-3-030-59105-2_5
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