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Treatment Options in Patients with Overactive Bladder: Initial and Pharmacological Management

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Non-Neurogenic Bladder Dysfunctions

Abstract

Overactive bladder syndrome (OAB) is a common disorder with significant impact on quality of life. To date the first-line management options are lifestyle modification and the pharmacological treatment. However, it is daily experience that these patients are often not satisfied with therapies. This may result from a choice of the drug not ideal for the characteristics of the patient that requires its use, or it may result from the underestimation of the comorbidities, or frailties, of the patient. All this results in high abandonment of therapies and a mistrust in being able to see a solution to the symptoms of overactive bladder. This chapter describes lifestyle modification, the drugs available for the treatment of overactive bladder, and analyses numerous critical issues often found in patients with overactive bladder.

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Abbreviations

ACh:

Acetylcholine

BOO:

Bladder outlet obstruction

BPH:

Benign prostate hypertrophy

CNS:

Central nervous system

DO:

Detrusor overactivity

LUTS:

Lower urinary tract symptoms

MUI:

Mixed urinary incontinence

OAB:

Overactive bladder syndrome

QOL:

Quality of life

SUI:

Stress urinary incontinence

UI:

Urinary incontinence

UUI:

Urgency urinary incontinence

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Balzarro, M., Antonelli, A. (2021). Treatment Options in Patients with Overactive Bladder: Initial and Pharmacological Management. In: Balzarro, M., Li Marzi, V. (eds) Non-Neurogenic Bladder Dysfunctions. Urodynamics, Neurourology and Pelvic Floor Dysfunctions. Springer, Cham. https://doi.org/10.1007/978-3-030-57393-5_3

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