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Diagnosis of Underactive Bladder in Female

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Non-Neurogenic Bladder Dysfunctions

Part of the book series: Urodynamics, Neurourology and Pelvic Floor Dysfunctions ((UNPFD))

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Abstract

Diagnosis of underactive bladder (UAB) is by clinical and urodynamic evaluation. The clinical evaluation is based firstly on the patient’s medical history, with the aim of assessing risk factors and sequelae associated with UAB, and secondly on an evaluation of urinary symptoms. However, the diagnosis of UAB from symptoms alone is difficult owing to the presence of symptoms that overlap with other bladder pathologies such as overactive bladder (OAB) or bladder outlet obstruction (BOO). We propose a new diagnostic algorithm for LUTS for distinguishing UAB, OAB and BOO patients. When diagnosis remains uncertain, urodynamics will evaluate contractility and a diagnosis of detrusor underactivity (DUA) will denote UAB. However, this is hindered by a lack of a gold-standard measurement for DUA in women. To date, the most effective diagnostic indicator of DUA in female patients is a PIP value <30.

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References

  1. Chapple CR, Osman NI, Birder L, van Koeveringe GA, Oelke M, Nitti VW, et al. The underactive bladder: a new clinical concept? Eur Urol. 2015;68:351–3. https://doi.org/10.1016/j.eururo.2015.02.030.

    Article  PubMed  Google Scholar 

  2. Smith PP, Birder LA, Abrams P, Wein AJ, Chapple CR. Detrusor underactivity and the underactive bladder: symptoms, function, cause-what do we mean? ICI-RS think tank 2014. Neurourol Urodyn. 2016;35:312–7. https://doi.org/10.1002/nau.22807.

    Article  PubMed  Google Scholar 

  3. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, et al. The standardisation of terminology in lower urinary tract function: report from the standardisation subcommittee of the International Continence Society. Urology. 2003;61:37–49.

    Article  Google Scholar 

  4. Jeong SJ, Kim HJ, Lee YJ, Lee JK, Lee BK, Choo YM, et al. Prevalence and clinical features of detrusor underactivity among elderly with lower urinary tract symptoms: a comparison between men and women. Korean J Urol. 2012;53:342–8. https://doi.org/10.4111/kju.2012.53.5.342.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Aldamanhori R, Chapple CR. Underactive bladder, detrusor underactivity, definition, symptoms, epidemiology, etiopathogenesis, and risk factors. Curr Opin Urol. 2017;27:293–9. https://doi.org/10.1097/MOU.0000000000000381.

    Article  PubMed  Google Scholar 

  6. Chapple CR, Osman NI, Birder L, Dmochowski R, Drake MJ, van Koeveringe G, et al. Terminology report from the International Continence Society (ICS) Working Group on Underactive Bladder (UAB). Neurourol Urodyn. 2018;37:2928–31. https://doi.org/10.1002/nau.23701.

    Article  PubMed  Google Scholar 

  7. Li X, Liao LM, Chen GQ, Wang ZX, Lu TJ, Deng H. Clinical and urodynamic characteristics of underactive bladder: data analysis of 1726 cases from a single center. Medicine (Baltimore). 2018;97:e9610. https://doi.org/10.1097/MD.0000000000009610.

    Article  Google Scholar 

  8. Araki I, Kitahara M, Oida T, Kuno S. Voiding dysfunction and Parkinsonʼs: urodynamic abnormalities and urinary symptoms. J Urol. 2000;164:1640–3.

    Article  CAS  Google Scholar 

  9. Bloch F, Pichon B, Bonnet AM, Pichon J, Vidailhet M, Roze E, et al. Urodynamic analysis in multiple system atrophy: characterisation of detrusor-sphincter dyssynergia. J Neurol. 2010;257:1986–91. https://doi.org/10.1007/s00415-010-5645-x.

    Article  PubMed  Google Scholar 

  10. Yamamoto T, Sakakibara R, Uchiyama T, Yamaguchi C, Ohno S, Nomura F, et al. Time-dependent changes and gender differences in urinary dysfunction in patients with multiple system atrophy. Neurourol Urodyn. 2014;33:516–23. https://doi.org/10.1002/nau.22441.

    Article  PubMed  Google Scholar 

  11. Chapple CR, Osman NI. The underactive detrusor. In: Wein AJ, Kavoussi LR, Partin AW, Peters CA, editors. Campbell-Walsh urology. 11th ed. Philadelphia, PA: Elsevier; 2016.

    Google Scholar 

  12. Litwiller SE, Frohman EM, Zimmern PE. Multiple sclerosis and the urologist. J Urol. 1999;161:743–57.

    Article  CAS  Google Scholar 

  13. Taylor JA, Kuchel GA. Detrusor underactivity: clinical features and pathogenesis of an underdiagnosed geriatric condition. J Am Geriatr Soc. 2006;54:1920–32.

    Article  Google Scholar 

  14. Gammie A, Kaper M, Dorrepaal C, Kos T, Abrams P. Signs and symptoms of detrusor underactivity: an analysis of clinical presentation and urodynamic tests from a large group of patients undergoing pressure flow studies. Eur Urol. 2016;69:361–9. https://doi.org/10.1016/j.eururo.2015.08.014.

    Article  PubMed  Google Scholar 

  15. Food and Drug Administration. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims; 2009.

    Google Scholar 

  16. Uren AD, Cotterill N, Harding C, Hillary C, Chapple C, Klaver M, et al. The development of the ICIQ-UAB: a patient reported outcome measure for underactive bladder. Neurourol Urodyn. 2019;38:996–1004. https://doi.org/10.1002/nau.23947.

    Article  PubMed  Google Scholar 

  17. Gani J, Hennessey D. The underactive bladder: diagnosis and surgical treatment options. Transl Androl Urol. 2017;6(Suppl 2):S186–95. https://doi.org/10.21037/tau.2017.04.07.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Hoag N, Gani J. Underactive bladder: clinical features, urodynamic parameters, and treatment. Int Neurourol J. 2015;19:185–9. https://doi.org/10.5213/inj.2015.19.3.185.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Groutz A, Gordon D, Lessing JB, Wolman I, Jaffa A, David MP. Prevalence and characteristics of voiding difficulties in women: are subjective symptoms substantiated by objective urodynamic data? Urology. 1999;54:268–72.

    Article  CAS  Google Scholar 

  20. Abarbanel J, Marcus EL. Impaired detrusor contractility in community-dwelling elderly presenting with lower urinary tract symptoms. Urology. 2007;69:436–40.

    Article  Google Scholar 

  21. Griffiths DJ. Editorial: bladder failure—a condition to reckon with. J Urol. 2003;169:1011–2.

    Article  Google Scholar 

  22. Griffiths D. Detrusor contractility–order out of chaos. Scand J Urol Nephrol Suppl. 2004;215:93–100.

    Article  Google Scholar 

  23. Lecamwasam HS, Yalla SV, Cravalho EG, Sullivan MP. The maximum watts factor as a measure of detrusor contractility independent of outlet resistance. Neurourol Urodyn. 1998;17:621–35.

    Article  CAS  Google Scholar 

  24. Griffiths DJ. Assessment of detrusor contraction strength or contractility. Neurourol Urodyn. 1991;10:1–18.

    Article  Google Scholar 

  25. Griffiths DJ, Constantinou CE, van Mastrigt R. Urinary bladder function and its control in healthy females. Am J Physiol. 1986;251:R225–30.

    CAS  PubMed  Google Scholar 

  26. Griffiths DJ. The mechanics of the urethra and of micturition. Br J Urol. 1973;45:497–507.

    Article  CAS  Google Scholar 

  27. Schafer W. Analysis of bladder-outlet function with the linearized passive urethral resistance relation, linPURR, and a disease-specific approach for grading obstruction: from complex to simple. World J Urol. 1995;3:47–58.

    Google Scholar 

  28. Abrams P. Bladder outlet obstruction index, bladder contractility index and bladder voiding efficiency: three simple indices to define bladder voiding function. BJU Int. 1999;84:14–5.

    Article  CAS  Google Scholar 

  29. Cucchi A, Quaglini S, Rovereto B. Proposal for a urodynamic redefinition of detrusor underactivity. J Urol. 2009;181:225–9.

    Article  Google Scholar 

  30. Cucchi A. Some observations on a condition of relatively lower detrusor contractility in stable versus unstable unobstructed bladders. Neurourol Urodyn. 1995;14:317–24.

    Article  CAS  Google Scholar 

  31. Cucchi A, Quaglini S, Guarnaschelli C, Rovereto B. Urodynamic findings suggesting two-stage development of idiopathic detrusor underactivity in adult men. Urology. 2007;70:75–9.

    Article  Google Scholar 

  32. Cucchi A, Quaglini S, Rovereto B. Different evolution of voiding function in underactive bladders with and without detrusor overactivity. J Urol. 2010;183:229–33. https://doi.org/10.1016/j.juro.2009.08.162.

    Article  PubMed  Google Scholar 

  33. Cucchi A, Quaglini S, Rovereto B. Development of idiopathic detrusor underactivity in women: from isolated decrease in contraction velocity to obvious impairment of voiding function. Urology. 2008;71(5):844–8. https://doi.org/10.1016/j.urology.2007.11.145.

    Article  PubMed  Google Scholar 

  34. Smith PP, Chalmers DJ, Feinn RS. Does defective volume sensation contribute to detrusor underactivity? Neurourol Urodyn. 2015;34:752–6. https://doi.org/10.1002/nau.22653.

    Article  PubMed  Google Scholar 

  35. Jiang YH, Kuo HC. Urothelial barrier deficits, suburothelial inflammation and altered sensory protein expression in detrusor underactivity. J Urol. 2017;197:197–203. https://doi.org/10.1016/j.juro.2016.07.071.

    Article  PubMed  Google Scholar 

  36. Yang TH, Chuang FC, Kuo HC. Urodynamic characteristics of detrusor underactivity in women with voiding dysfunction. PLoS One. 2018;13:e0198764. https://doi.org/10.1371/journal.pone.0198764.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  37. Resnick NA, Yalla SV. Detrusor hyperactivity with impaired contractile function. An unrecognized but common cause of incontinence in elderly patients. JAMA. 1987;257:3076–81.

    Article  CAS  Google Scholar 

  38. Wagg A, Chen LK, Johnson T, Kirschner-Hermanns R, Kuchel G, Markland A, et al. Incontinence in frail older persons. In: Abrams P, Cardozo L, Wagg A, Wien A, editors. Incontinence. 6th ed. Tokyo: ICUD and ICS; 2016. p. 1309–441.

    Google Scholar 

  39. Gammie A, Kaper M, Steup A, Yoshida S, Dorrepaal C, Kos T, et al. What are the additional signs and symptoms in patients with detrusor underactivity and coexisting detrusor overactivity? Neurourol Urodyn. 2018;37:2220–5. https://doi.org/10.1002/nau.23565.

    Article  PubMed  Google Scholar 

  40. Stav K, Shilo Y, Zisman A, Lindner A, Leibovici D. Comparison of lower urinary tract symptoms between women with detrusor overactivity and impaired contractility, and detrusor overactivity and preserved contractility. J Urol. 2013;189:2175–8. https://doi.org/10.1016/j.juro.2012.11.178.

    Article  PubMed  Google Scholar 

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Natale, F., Trama, F. (2021). Diagnosis of Underactive Bladder in Female. In: Balzarro, M., Li Marzi, V. (eds) Non-Neurogenic Bladder Dysfunctions. Urodynamics, Neurourology and Pelvic Floor Dysfunctions. Springer, Cham. https://doi.org/10.1007/978-3-030-57393-5_10

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  • DOI: https://doi.org/10.1007/978-3-030-57393-5_10

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