Abstract
Oral herpes is a disease caused mainly by herpes simplex virus-1 (HSV-1) and primarily affects the face, mouth and throat. It causes pain, burning, tingling or itching at the infection site which is normally followed by clusters of blisters. After the first infection, the disease can recur as episodes of cold sores on the lips. It’s usually mild and self-limiting, lasting 2–3 weeks, but can cause severe disease in those who are at risk such as the immunocompromised. It’s a very common disease – 90% of the world’s population are infected by the age of 40 years, and 40% of these will experience a recurrent infection. Infection is lifelong. Treatment includes medication for the relief of pain and fever – topical medications like anaesthetics and anti-virals may also be useful. Adequate fluid intake is important to avoid dehydration. Oral anti-viral agents are available for treating severe or frequently recurring infections.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Want to Know More?
American Dental Association. https://ada.com/conditions/herpes-labialis/
American Family Physician. https://www.aafp.org/afp/2010/1101/p1075.html
DermNet, New Zealand. https://www.dermnetnz.org/cme/viral-infections/herpes-simplex/
Mayo Clinic, USA. https://www.mayoclinic.org/diseases-conditions/cold-sore/symptoms-causes/syc-20371017
National Health Service, UK. https://www.nhs.uk/conditions/cold-sores/
National Institute for Clinical Care and Excellence (NICE), UK. Herpes simplex – oral, 2016. https://cks.nice.org.uk/herpes-simplex-oral#!topicSummary
Patient Info, UK. https://patient.info/doctor/oral-herpes-simplex
Primary Care Dermatology Society, UK. http://www.pcds.org.uk/clinical-guidance/herpes-simplex
School of Medicine at Mount Sinai, USA. https://www.mountsinai.org/health-library/diseases-conditions/herpes-oral
World Health Organisation. https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus
Ayoade FO. Herpes Simplex. Medscape from WebMD, 2018. https://emedicine.medscape.com/article/218580-overview
Lorenz BD. Herpes simplex virus infection. BMJ Best Practice, BMJ Publishing Group, 2019. https://bestpractice.bmj.com/topics/en-gb/53
Opstelten W, Neven AK, Eekhof J. Treatment and prevention of herpes labialis. Canadian Family Physician. 2008 Dec;54(12):1683-7. PMID: 19074705
Saleh D, Sharma S. Herpes Simplex Type 1. Treasure Island (FL): StatPearls Publishing LLC; 2019. https://www.ncbi.nlm.nih.gov/books/NBK482197/
Worrall G. Herpes labialis. BMJ Clinical Evidence. 2009 Sep 23;2009. pii: 1704. PMID: 21726482
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Wilson, M., Wilson, P.J.K. (2021). Cold Sores. In: Close Encounters of the Microbial Kind. Springer, Cham. https://doi.org/10.1007/978-3-030-56978-5_24
Download citation
DOI: https://doi.org/10.1007/978-3-030-56978-5_24
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-56977-8
Online ISBN: 978-3-030-56978-5
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)