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Neuroendocrine Neoplasms of the Upper Aerodigestive Tract, Ear, and Salivary Glands

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The Spectrum of Neuroendocrine Neoplasia

Abstract

Neuroendocrine neoplasms (NENs) of the head and neck (H&N) region include a heterogeneous group of neoplastic proliferations arising in the nasal cavity, paranasal sinuses, nasopharynx, larynx, salivary glands, middle ear, and skin. In addition to epithelial neoplasms, H&N paraganglioma and olfactory neuroblastoma can be included in this group. The morphological and clinical features of H&N NENs depend on several different factors, including their degree of differentiation, site of origin, and molecular background. Indeed, H&N NENs encompass a wide spectrum of neoplasms, ranging from indolent neuroendocrine tumors to highly aggressive neuroendocrine carcinomas.

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Author information

Authors and Affiliations

  1. Pathology Unit, Department of Medicine and Surgery, University of Insubria, Varese, Italy

    Silvia Uccella

  2. Institute of Pathology, University Hospital and University of Lausanne, Lausanne, Switzerland

    Stefano La Rosa

Authors
  1. Silvia Uccella
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  2. Stefano La Rosa
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Corresponding author

Correspondence to Silvia Uccella .

Editor information

Editors and Affiliations

  1. University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, OH, USA

    Sylvia L. Asa

  2. Institute of Pathology, University Hospital of Lausanne, Lausanne, Vaud, Switzerland

    Stefano La Rosa

  3. Department of Pathology, University Health Network, Toronto, ON, Canada

    Ozgur Mete

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Uccella, S., La Rosa, S. (2021). Neuroendocrine Neoplasms of the Upper Aerodigestive Tract, Ear, and Salivary Glands. In: Asa, S.L., La Rosa, S., Mete, O. (eds) The Spectrum of Neuroendocrine Neoplasia. Springer, Cham. https://doi.org/10.1007/978-3-030-54391-4_6

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  • DOI: https://doi.org/10.1007/978-3-030-54391-4_6

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  • Online ISBN: 978-3-030-54391-4

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