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The International System for Reporting Serous Fluid Cytopathology: Introduction and Overview of Diagnostic Terminology and Reporting

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The International System for Serous Fluid Cytopathology

Abstract

The International System (TIS) for Reporting Serous Fluid Cytopathology is comprised of six diagnostic categories adopted from previous cytopathology reporting models. These include Nondiagnostic (ND), Negative for Malignancy (NFM), Atypia of Undetermined Significance (AUS), Suspicious for Malignancy (SFM), Malignant-Primary (MAL-P), and Malignant-Secondary (MAL-S). We discuss the rationale for and use of this proposed terminology, along with a meta-analysis-supported risk of malignancy associated with each category and the limitations of the existing literature.

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Author information

Authors and Affiliations

  1. Gynecologic, Breast and Cytopathology, Joint Pathology Center, Silver Spring, MD, USA

    Barbara Crothers

  2. Department of Pathology & Laboratory Medicine, University of Pennsylvania Medical Center, Perelman School of Medicine, Philadelphia, PA, USA

    Zubair Baloch

  3. Cellular Pathology, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

    Ashish Chandra

  4. Renaissance School of Medicine, Stony Brook University, Department of Pathology, Stony Brook, NY, USA

    Sahar Farahani

  5. University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine and Wisconsin State Laboratory of Hygiene, Madison, WI, USA

    Daniel Kurtycz

  6. Department of Pathology, Medical Faculty of Porto University and Unit of Molecular Pathology, Institute of Molecular Pathology and Immunology, Porto University, Porto, Portugal

    Fernando Schmitt

Authors
  1. Barbara Crothers
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  2. Zubair Baloch
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  3. Ashish Chandra
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  4. Sahar Farahani
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  5. Daniel Kurtycz
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  6. Fernando Schmitt
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Corresponding author

Correspondence to Barbara Crothers .

Editor information

Editors and Affiliations

  1. Cellular Pathology, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

    Ashish Chandra

  2. Gynecology, Breast and Cytopathology Joint Pathology Center, Silver Spring, MD, USA

    Barbara Crothers

  3. University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine and Wisconsin State Laboratory of Hygiene, Madison, WI, USA

    Daniel Kurtycz

  4. Department of Pathology, Medical Faculty of Porto University and Unit of Molecular Pathology, Institute of Molecular Pathology and Immunology Porto University, Porto, Portugal

    Fernando Schmitt

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Crothers, B., Baloch, Z., Chandra, A., Farahani, S., Kurtycz, D., Schmitt, F. (2020). The International System for Reporting Serous Fluid Cytopathology: Introduction and Overview of Diagnostic Terminology and Reporting. In: Chandra, A., Crothers, B., Kurtycz, D., Schmitt, F. (eds) The International System for Serous Fluid Cytopathology. Springer, Cham. https://doi.org/10.1007/978-3-030-53908-5_1

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  • DOI: https://doi.org/10.1007/978-3-030-53908-5_1

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-53907-8

  • Online ISBN: 978-3-030-53908-5

  • eBook Packages: MedicineMedicine (R0)

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