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The Quantity and Quality of Surgical Trials in Pancreatic Cancer

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Textbook of Pancreatic Cancer

Abstract

Randomized controlled trials represent the foundation for evidence-based decision making in clinical practice. However, especially in complex surgical areas such as pancreatic cancer surgery, high quality evidence from surgical randomized controlled trials was usually scarce. In recent years both, the quantity as well as the quality of surgical trials focusing on pancreatic cancer have increased. Nevertheless, there are still evidence gaps regarding specific issues of surgical treatment of pancreatic cancer. Shortcomings remain in trial methodology and reporting for individual domains such as blinding and selective reporting. Novel methods, including priority setting partnerships and evidence mapping, could help to identify and prioritize the most patient-relevant research questions that need to be answered by collaborative research projects with bundled forces in the future.

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Authors and Affiliations

  1. Department of General, Visceral and Transplantation Surgery, University Heidelberg, Heidelberg, Germany

    Felix J. Hüttner, Pascal Probst & Markus K. Diener

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  1. Stavanger University Hospital, The University of Bergen, Bergen, Norway

    Kjetil Søreide

  2. Chirurgie (VTT), Innsbruck Medical University, Innsbruck, Tirol, Austria

    Stefan Stättner

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Hüttner, F.J., Probst, P., Diener, M.K. (2021). The Quantity and Quality of Surgical Trials in Pancreatic Cancer. In: Søreide, K., Stättner, S. (eds) Textbook of Pancreatic Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-53786-9_7

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