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Vascular Supply: Important Arterial and Venous Variants

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Textbook of Pancreatic Cancer
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Abstract

The vascular anatomy of the pancreas permits its partial resection, thereby greatly enhancing life expectancy of patients with pancreatic cancer while limiting morbidity associated with a total pancreatectomy. Variations in arterial anatomy are common, directly relate to the embryology of the pancreas, and need to be understood by the surgeon to prevent inadvertent injury with potentially catastrophic consequences during resection. Variation in venous anatomy, while also common, are of lesser importance when planning standard resection. Differences in venous anatomy can, however, become relevant when planning venous resection and reconstruction.

This chapter describes normal pancreatic vascular anatomy in detail, while highlighting its common variants and their relevance to pancreatic resection providing points of clinical reference to aid understanding. This knowledge is essential in order to perform a standard pancreatic resection safely. An appreciation of specific anatomical variants and their implications may also allow alternate approaches when resecting locally advanced cancers.

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References

  1. Shinde RS, et al. Cutting-edge strategies for borderline resectable pancreatic cancer. Ann Gastroenterol Surg. 2019;3(4):368–72.

    Article  Google Scholar 

  2. Assi HA, et al. Surgery versus surveillance for well-differentiated, nonfunctional pancreatic neuroendocrine tumors: an 11-year analysis of the National Cancer Database. Oncologist. 2020;25(2):e276–83.

    Article  CAS  Google Scholar 

  3. Huang Q, et al. Surgical resection for metastatic tumors in the pancreas: a single-center experience and systematic review. Ann Surg Oncol. 2019;26(6):1649–56.

    Article  Google Scholar 

  4. Scholten L, et al. Outcome and long-term quality of life after total pancreatectomy (PANORAMA): a nationwide cohort study. Surgery. 2019;166(6):1017–26.

    Article  Google Scholar 

  5. Koike H, et al. Modelling human hepato-biliary-pancreatic organogenesis from the foregut-midgut boundary. Nature. 2019;574(7776):112–6.

    Article  CAS  Google Scholar 

  6. Jennings RE, et al. Human pancreas development. Development. 2015;142(18):3126–37.

    Article  CAS  Google Scholar 

  7. Larsen HL, Grapin-Botton A. The molecular and morphogenetic basis of pancreas organogenesis. Semin Cell Dev Biol. 2017;66:51–68.

    Article  CAS  Google Scholar 

  8. Walker TG. Mesenteric vasculature and collateral pathways. Semin Intervent Radiol. 2009;26(3):167–74.

    Article  Google Scholar 

  9. Jin GY, et al. Anatomical variations of the origin of the segment 4 hepatic artery and their clinical implications. Liver Transpl. 2008;14(8):1180–4.

    Article  Google Scholar 

  10. Hikspoors J, et al. The fate of the vitelline and umbilical veins during the development of the human liver. J Anat. 2017;231(5):718–35.

    Article  CAS  Google Scholar 

  11. Carneiro C, et al. All about portal vein: a pictorial display to anatomy, variants and physiopathology. Insights Imaging. 2019;10(1):38.

    Article  Google Scholar 

  12. Collardeau-Frachon S, Scoazec JY. Vascular development and differentiation during human liver organogenesis. Anat Rec (Hoboken). 2008;291(6):614–27.

    Article  Google Scholar 

  13. di Francesco F, et al. Pre-duodenal portal vein reconstruction at liver transplantation: the challenges and a solution. Liver Transpl. 2019;25(12):1841–4.

    Article  Google Scholar 

  14. Abe H, et al. Regressing vitelline vein and the initial development of the superior mesenteric vein in human embryos. Okajimas Folia Anat Jpn. 2017;94(3):87–92.

    Article  Google Scholar 

  15. Macchi V, et al. Anatomo-radiological patterns of pancreatic vascularization, with surgical implications: clinical and anatomical study. Clin Anat. 2017;30(5):614–24.

    Article  Google Scholar 

  16. Bertelli E, et al. The arterial blood supply of the pancreas: a review. II. The posterior superior pancreaticoduodenal artery. An anatomical and radiological study. Surg Radiol Anat. 1996;18(1):1–9.

    Article  CAS  Google Scholar 

  17. Bertelli E, et al. The arterial blood supply of the pancreas: a review. III. The inferior pancreaticoduodenal artery. An anatomical review and a radiological study. Surg Radiol Anat. 1996;18(2):67–74.

    Article  CAS  Google Scholar 

  18. Katz MH, et al. Anatomy of the superior mesenteric vein with special reference to the surgical management of first-order branch involvement at pancreatoduodenectomy. Ann Surg. 2008;248(6):1098–102.

    Google Scholar 

  19. Kim HJ, et al. Radiologic anatomy of the superior mesenteric vein and branching patterns of the first jejunal trunk: evaluation using multi-detector row CT venography. Surg Radiol Anat. 2007;29(1):67–75.

    Article  Google Scholar 

  20. Ramesh Babu CS, Sharma M. Biliary tract anatomy and its relationship with venous drainage. J Clin Exp Hepatol. 2014;4(Suppl 1):S18–26.

    Article  Google Scholar 

  21. Stefura T, et al. The venous trunk of henle (gastrocolic trunk): a systematic review and meta-analysis of its prevalence, dimensions, and tributary variations. Clin Anat. 2018;31(8):1109–21.

    Article  Google Scholar 

  22. Michels NA. Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg. 1966;112(3):337–47.

    Article  CAS  Google Scholar 

  23. Gkaragkounis A, et al. Celiac trunk and hepatic arteries: anatomical variations of liver arterial supply as detected with multidetector computed tomography in 1,520 patients and its clinical importance. Clin Anat. 2019.

    Google Scholar 

  24. Hicks CW, et al. Management of type 9 hepatic arterial anatomy at the time of pancreaticoduodenectomy: considerations for preservation and reconstruction of a completely replaced common hepatic artery. J Gastrointest Surg. 2016;20(7):1400–4.

    Article  Google Scholar 

  25. Bertelli E, et al. The arterial blood supply of the pancreas: a review. IV. The anterior inferior and posterior pancreaticoduodenal aa., and minor sources of blood supply for the head of the pancreas. An anatomical review and radiologic study. Surg Radiol Anat. 1997;19(4):203–12.

    CAS  PubMed  Google Scholar 

  26. Bull DA, et al. Hepatic ischemia, caused by celiac axis compression, complicating pancreatoduodenectomy. Ann Surg. 1993;217(3):244–7.

    Google Scholar 

  27. Bramis K, et al. Whipple’s procedure complicated by celiac artery stenosis: case report and review of treatment options. Cancer Res Front. 2016;2(3):427–31.

    Article  Google Scholar 

  28. Covantev S, Mazuruc N, Belic O. The arterial supply of the distal part of the pancreas. Surg Res Pract. 2019;2019:5804047.

    CAS  PubMed  PubMed Central  Google Scholar 

  29. Pinal-Garcia DF, et al. The celiac trunk and its anatomical variations: a cadaveric study. J Clin Med Res. 2018;10(4):321–9.

    Article  Google Scholar 

  30. Buhler A. Uber eine Anastomose zwischen den Stammen der Art. coeliaca und der Art. mesenterica superior. Morph Jahrb. 1904;32:185–8.

    Google Scholar 

  31. Egorov VI, et al. Liver blood supply after a modified Appleby procedure in classical and aberrant arterial anatomy. World J Gastrointest Surg. 2013;5(3):51–61.

    Article  Google Scholar 

  32. Latona JA, et al. Modified Appleby procedure with arterial reconstruction for locally advanced pancreatic adenocarcinoma: a literature review and report of three unusual cases. J Gastrointest Surg. 2016;20(2):300–6.

    Article  Google Scholar 

  33. Egorov VI, et al. Spleen-preserving distal pancreatectomy with resection of the splenic vessels. Should one rely on the short gastric arteries? JOP. 2011;12(5):445–57.

    PubMed  Google Scholar 

  34. Kimura W, et al. Spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein. World J Gastroenterol. 2007;13(10):1493–9.

    Article  Google Scholar 

  35. Mosca S, et al. The superior horizontal pancreatic artery of Popova: a review and an anatomoradiological study of an important morphological variant of the pancreatica magna artery. Surg Radiol Anat. 2014;36(10):1043–9.

    Article  CAS  Google Scholar 

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Correspondence to Declan F. J. Dunne .

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Szatmary, P., Dunne, D.F.J. (2021). Vascular Supply: Important Arterial and Venous Variants. In: Søreide, K., Stättner, S. (eds) Textbook of Pancreatic Cancer. Springer, Cham. https://doi.org/10.1007/978-3-030-53786-9_12

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  • DOI: https://doi.org/10.1007/978-3-030-53786-9_12

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