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Lower Limb Ulcers

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Practical Management of Systemic Sclerosis in Clinical Practice

Part of the book series: In Clinical Practice ((ICP))

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Abstract

Lower limb ulcers may represent real clinical challenge in patients with systemic sclerosis (SSc). They are often multifactorial, long-lasting and difficult to treat. In addition to microangiopathy, macrovascular arterial and venous involvement may overlap and cause ulcer formation. Other local factors, as calcinosis and hyperkeratosis can contribute. Several types of lesions with different aetiology may occur, even in the same patient. Systematic clinical evaluation and diagnostic work-up are mandatory for proper ulcer classification that is essential for their management, since diverse lesions may require different treatment.

The learning objectives of this chapter are to understand etiopathogenesis of lower limb ulcers in SSc, to comprehend their clinical assessment and management.

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Authors and Affiliations

  1. Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

    Jelena Blagojevic & Silvia Bellando-Randone

  2. Department of Geriatric Medicine, Division of Rheumatology and Scleroderma Unit, AOUC, Florence, Italy

    Jelena Blagojevic & Silvia Bellando-Randone

Authors
  1. Jelena Blagojevic
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  2. Silvia Bellando-Randone
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Correspondence to Jelena Blagojevic .

Editor information

Editors and Affiliations

  1. University of Florence, Firenze, Firenze, Italy

    Marco Matucci-Cerinic

  2. University College London, Royal Free Hospital, London, UK

    Christopher P. Denton

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Blagojevic, J., Bellando-Randone, S. (2021). Lower Limb Ulcers. In: Matucci-Cerinic, M., Denton, C.P. (eds) Practical Management of Systemic Sclerosis in Clinical Practice. In Clinical Practice. Springer, Cham. https://doi.org/10.1007/978-3-030-53736-4_11

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  • DOI: https://doi.org/10.1007/978-3-030-53736-4_11

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-53735-7

  • Online ISBN: 978-3-030-53736-4

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