Skin Cancer and Uveal Melanoma

Abstract

Skin cancer is the most common cancer diagnosed in the United States annually with the vast majority presenting as basal cell carcinoma followed by squamous cell carcinoma, melanoma, and Merkel cell carcinoma. While surgery is the mainstay of treatment, this section aims to reinforce the indications of radiation therapy and rationale of these indications backed by clinical research findings. This section has also been expanded to include updates in clinical staging per the American Joint Committee on Cancer and novel therapeutic agents. Given the rarity of uveal melanoma, this disease entity is briefly included in the same chapter as cutaneous melanoma as radiation is an integral component of management organ preservation.