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Healthy Worms

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Explaining Health Across the Sciences

Part of the book series: Healthy Ageing and Longevity ((HAL,volume 12))

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Abstract

Health is often seen as the attractive opposite to disease but what are the molecular mechanisms that underpin health and can we target these pathways to improve health? Model organisms have been instrumental in defining the molecular genetics of complex biological processes, including longevity, and now they are increasingly being used to investigate health. In this chapter, we review some of the insights that have been gained by studying health and healthspan in the soil nematode Caenorhabditis elegans. Interestingly, several gene mutations and interventions have been shown to improve health in C. elegans offering possibilities of translation to humans.

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Authors and Affiliations

  1. Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, 9220, Aalborg, Denmark

    Rikke Hindsgaul Harders, Katrine Vogt Møller, Maria Grymer Metz Mørch & Anders Olsen

  2. Department of Molecular Medicine, The Scripps Research Institute, Jupiter, Florida, USA

    Matthew S. Gill

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  1. Rikke Hindsgaul Harders
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  2. Katrine Vogt Møller
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  3. Maria Grymer Metz Mørch
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  4. Matthew S. Gill
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  5. Anders Olsen
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Correspondence to Matthew S. Gill or Anders Olsen .

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  1. Philosophy and History of Ideas, Aarhus University, Aarhus, Denmark

    Jonathan Sholl

  2. Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

    Suresh I.S. Rattan

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Harders, R.H., Møller, K.V., Mørch, M.G.M., Gill, M.S., Olsen, A. (2020). Healthy Worms. In: Sholl, J., Rattan, S.I. (eds) Explaining Health Across the Sciences. Healthy Ageing and Longevity, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-030-52663-4_20

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