Abstract
Soft tissue sarcomas (STS) are rare malignancies, accounting for 1% of all tumors. The most common site of origin is the extremities (50%), followed by the retroperitoneum (20%), the viscera (15%), the superficial trunk (10%) and the head and neck (5%). Local recurrence is more common among low-grade tumors, while high-grade STS tend to spread distantly. Optimal surgery, with en-bloc resection and clear margins is the only potential curative treatment of localized STS, but it should be tailored to the specific histology and be part of a multidisciplinary management of the disease. A multidisciplinary approach is the goal in all cases of STS. Treatment strategies for all patients must be the result of the consensus of the multidisciplinary team including surgical oncologists, pathologists, radiologists, radiation therapists, and medical oncologists. Given the complexity of the disease and the heterogeneity of the various presentations, it is necessary that the management of sarcoma patients is centralized to referral centers and/or within reference networks that share multidisciplinary expertise. These centers should treat a high number of patients annually and be involved in ongoing clinical trials that allow for the best tailored treatment for each specific case.
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Spolverato, G., Quagliuolo, V., Gronchi, A. (2021). Volume-Outcome Relationship in Surgery of Soft Tissue Sarcomas. In: Montorsi, M. (eds) Volume-Outcome Relationship in Oncological Surgery. Updates in Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-51806-6_8
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DOI: https://doi.org/10.1007/978-3-030-51806-6_8
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