Abstract
The first linkage of healthcare databases that laid the basis for the PHARMO Database Network dates back to the first quarter of 1989 and was an initiative of Prof. Dr. B.Ch. Stricker and Dr. R.M.C. Herings. Drug exposure files of community pharmacies (now the Out-patient Pharmacy Database) were linked to the hospital administration records of the national Hospital Database creating the PHARmacoMOrbidity linkage. With these linked data, questions on the use, effectiveness, and safety of drugs in daily clinical practice could be answered.
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References
Bezemer ID, van der Berg EJ, Herings R et al (2016) Anticoagulant treatment after VTE in the Netherlands: a retrospective cohort study. Jacobs J Hematol 2(2):030
Bezemer ID, Verhamme KM, Gini R et al (2016) Use of oral contraceptives in three European countries: a population-based multi-database study. Eur J Contracept Reprod Health Care 21(1):81–87. https://doi.org/10.3109/13625187.2015.1102220
Castellsague J, Kuiper JG, Pottegard A et al (2018) A cohort study on the risk of lymphoma and skin cancer in users of topical tacrolimus, pimecrolimus, and corticosteroids (Joint European Longitudinal Lymphoma and Skin Cancer Evaluation—JOELLE study). Clin Epidemiol 10:299–310. https://doi.org/10.2147/clep.S146442
Heintjes EM, Overbeek JA, Penning-van Beest FJ et al (2016) Post authorization safety study comparing quetiapine to risperidone and olanzapine. Hum Psychopharmacol 31(4):304–312. https://doi.org/10.1002/hup.2539
Herings RMC, Pedersen L (2012) Pharmacy-based medical record linkage systems. In: Strom BL, Kimmel SE, Hennessy S (eds) Pharmacoepidemiology, 5th edn. Wiley, Chichester, pp 271–286
Houben E, van Haalen HG, Sparreboom W et al (2017) Chemotherapy for ovarian cancer in the Netherlands: a population-based study on treatment patterns and outcomes. Med Oncol 34(4):50. https://doi.org/10.1007/s12032-017-0901-x
Houben E, Johansson S, Nagy P et al (2018) Observational cohort study: safety outcomes in children using proton pump inhibitors or histamine-2 receptor antagonists. Curr Med Res Opin 34(4):577–583. https://doi.org/10.1080/03007995.2017.1407302
Houben E, Smits E, Overbeek JA et al (2018) No evidence for an association between renal function and serious bleeding events in patients treated with coumarins: a population-based study. Ann Pharmacother 52(3):221–234. https://doi.org/10.1177/1060028017735340
Houben E, Smits E, Pimenta JM et al (2019) Increased risk of morbidities and health-care utilisation in children born following preterm labour compared with full-term labour: a population-based study. J Paediatr Child Health 55(4):446–453. https://doi.org/10.1111/jpc.14225
IKNL-Netherlands Comprehensive Cancer Organisation (2020) https://www.iknl.nl/. Accessed 17 Jan 2020
Korhonen P, Heintjes EM, Williams R et al (2016) Pioglitazone use and risk of bladder cancer in patients with type 2 diabetes: retrospective cohort study using datasets from four European countries. BMJ 354:i3903. https://doi.org/10.1136/bmj.i3903
Kuiper JG, Bezemer ID, Driessen MT et al (2016) Rates of prostate surgery and acute urinary retention for benign prostatic hyperplasia in men treated with dutasteride or finasteride. BMC Urol 16(1):53. https://doi.org/10.1186/s12894-016-0170-6
Kuiper J, Musingarimi P, Tapprich C et al (2017) Chemotherapy exposure and outcomes of chronic lymphoid leukemia patients. J Clin Intensive Care Med 2:025–033
Kuiper JG, Sanchez RJ, Houben E et al (2017) Use of lipid-modifying therapy and LDL-C goal attainment in a high-cardiovascular-risk population in the Netherlands. Clin Ther 39(4):819-827.e811. https://doi.org/10.1016/j.clinthera.2017.03.001
Kuiper JG, van Herk-Sukel MPP, Castellsague J et al (2018) Use of topical tacrolimus and topical pimecrolimus in four European countries: a multicentre database cohort study. Drugs Real World Outcomes 5(2):109–116. https://doi.org/10.1007/s40801-018-0133-1
Overbeek JA, Heintjes EM, Prieto-Alhambra D et al (2017) Type 2 diabetes mellitus treatment patterns across Europe: a population-based multi-database study. Clin Ther 39(4):759–770. https://doi.org/10.1016/j.clinthera.2017.02.008
Overbeek JA, Heintjes EM, Huisman EL et al (2018) Clinical effectiveness of liraglutide vs basal insulin in a real-world setting: evidence of improved glycaemic and weight control in obese people with type 2 diabetes. Diabetes Obes Metab 20(9):2093–2102. https://doi.org/10.1111/dom.13335
Overbeek JA, van Herk-Sukel MPP, Vissers PAJ et al (2019) Type 2 diabetes, but not insulin (analog) treatment, is associated with more advanced stages of breast cancer: a national linkage of cancer and pharmacy registries. Diabetes Care 42(3):434–442. https://doi.org/10.2337/dc18-2146
PALGA (2020) The nationwide network and registry of histopathology and cytopathology. https://www.palga.nl/. Accessed 17 Jan 2020
Penning-van Beest FJ, Overbeek JA, Smulders M et al (2011) Evaluation of smoking cessation drug use and outcomes in the Netherlands. J Med Econ 14(1):124–129. https://doi.org/10.3111/13696998.2010.551165
PRN-The Netherlands Perinatal Registry (2020) Perined. https://www.perined.nl/, 17 Jan 2020
van Herk-Sukel MP, van de Poll-Franse LV, Lemmens VE et al (2010) New opportunities for drug outcomes research in cancer patients: the linkage of the Eindhoven Cancer Registry and the PHARMO Record Linkage System. Eur J Cancer 46(2):395–404. https://doi.org/10.1016/j.ejca.2009.09.010
van Herk-Sukel MP, Shantakumar S, Penning-van Beest FJ et al (2013) Pulmonary embolism, myocardial infarction, and ischemic stroke in lung cancer patients: results from a longitudinal study. Lung 191(5):501–509. https://doi.org/10.1007/s00408-013-9485-1
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Bakker, M., Herings, R. (2021). PHARMO Database Network. In: Sturkenboom, M., Schink, T. (eds) Databases for Pharmacoepidemiological Research. Springer Series on Epidemiology and Public Health. Springer, Cham. https://doi.org/10.1007/978-3-030-51455-6_7
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