Abstract
Knowledge of the molecular mechanisms responsible for testicular failure still remains poor. The testicular volume, the histological features, and the serologic markers of gonadal function vary in different stages of life. The extra genetic material could play an important role in the pathophysiology of testicular development. It is possible that the testicular defect is primarily found in the germ cells or in an abnormal gonadal microenvironment.
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Calogero, A.E., Condorelli, R.A., La Vignera, S. (2020). Testicular Development. In: Garolla, A., Corona, G. (eds) Klinefelter’s Syndrome. Trends in Andrology and Sexual Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-51410-5_11
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