Recurrent Epistaxis from Kiesselbach’s Area Syndrome (REKAS)

Abstract

Vascular diseases are a major threat to human health nowadays. Cardiovascular diseases, including coronary heart disease and a stroke, are the leading cause of death in the United States and Europe. Several risk factors (i.e., stressful life, overweight, physical inactivity, smoking, hypertension, and diabetes mellitus; high levels of cholesterol and lipids; and, so far only hypothetically, the genetic predisposition to the development of the acute coronary syndrome because of certain deletion of some of the chromosomes that causes both the development of some of the dominantly inherited types of nasal septal deformities, i.e., types 5 and 6) are associated with the development of cardiovascular disease. Hypertension and cardiovascular disease, including atherosclerosis, cardiac hypertrophy, and ischemic disease, nowadays have been increasingly recognized as inflammatory diseases. In recent years, this hypothesis has led to heightened interest in studying the role of inflammatory cytokines in the pathogenesis of this diseases. Like arteries, the veins are also a part of vascular system and have their own pathology. In this chapter, recurrent epistaxis from Kiesselbach’s area syndrome (REKAS) is presented.