Abstract
During the last decade, biomedical applications of nanoparticles describes the most interesting and investigated applications of nanoparticles, emphasising their therapeutic impact. There have been enormous developments in utilising the power of nanotechnology in various fields including biomedical sciences. The most important biomedical applications of nanoparticles are in disease diagnosis and treatment. Functionalised nanoparticles possess unique properties as contrast agents for dual and even triple modal imaging. The potential of these new generation nanoparticles in targeted drug delivery has revolutionised safe and effective pharmacotherapies for complex diseases. One more step ahead, theranostic nanoparticles are equipped with dual capabilities for disease diagnosis as well as treatment. Specifically, designed nanoparticles have also been utilised to improve the delivery and efficiency of different vaccines, including their application in cancer immunotherapy. This chapter provides an overview of the biomedical applications of nanoparticles and recent advancements in this area on the basis of current research. Progress made in the therapy of severe diseases, such as cancer and difficult infections, is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The chapter highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect, and also anticancer strategies. Nanoparticles are minute particles that produce a major change in the healthcare and biomedical industry. It is not restricted to any field and its presence is observed in every field of biomedicine from diagnosis to treatment to implants to cosmetics.
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References
Allahverdiyev A, Rafailovich M. Coping with antibiotic resistance: combining nanoparticles with antibiotics and other antimicrobial agents. Expert Rev Anti-Infect Ther. 2011;9(11):1035–52.
Amin MT, Alazba AA, Manzoor U. A review of removal of pollutants from water/wastewater using different types of nanomaterials. Adv Mater Sci Eng. 2014;2014:1–25.
Bonelmekki M. An introduction to nanoparticles and nanotechnology. IOP Concise Phys. 2017;2017:1–14.
Chan JM, Zhang L, Yuet KP, Liao G, Rhee J, Langer R, et al. PLGA – Lecithin – PEG Core – shell nanoparticles for controlled drug delivery. Biomaterials. 2009;30(8):1627–34.
El Ansary A, Faddah LM. Nanoparticles as biochemical sensors. Nanotechnol Sci Appl. 2010;3:65–76.
Engel G. The need for a new medical model : a challenge for biomedicine. Sci New Ser. 1977;196(4286):129–36.
Fakruddin M, Hossain Z, Afroz H. Prospects and applications of nanobiotechnology : a medical perspective. J Nanobiotechnol. 2012;10(31):1–8.
Harris DL, Graffagnini MJ. Nanomaterials in medical devices: a snapshot of markets, technologies and companies. Nanotechnol Law Bus. 2006;2007(255):415–22.
Herranz F, Almarza E, RodrÃguez I. The application of nanoparticles in gene therapy and magnetic resonance imaging. Natl Inst Health. 2012;74(7):577–91.
Ioannou D, Griffin DK. Nanotechnology and molecular cytogenetics: the future has not yet arrived. Nano Rev. 2010;1(5117):1–14.
Kundu B, Kurland NE, Bano S, Patra C, Engel FB, Yadavalli VK, et al. Silk Proteins for Biomedical Applications : Bioengineering Perspectives. Prog Polym Sci. 2014;39(2):251–67.
Maojo V, Fritts M. Nanoinformatics: developing new computing applications for nanomedicine. Comput Sci Eng. 2012;94(6):521–39.
Prajapati P. Overview on applications of nanoparticles in cosmetics. Asian J Pharm Sci Res. 2011;1(2):40–55.
Quirke V, Gaudillière JP. The era of biomedicine: science, medicine, and public health in Britain and France after the Second World War. Med Hist. 2008;52(4):441–52.
Remião MH, Segatto NV, Pohlmann A, Guterres SS, Seixas FK, Collares T. The potential of nanotechnology in medically assisted reproduction. Perspective. 2018;8:1–9.
Rico CM. Chemistry, biochemistry of nanoparticles, and their role in antioxidant defense system in plants. In: Nanotechnology and plant sciences. Cham: Springer; 2015. p. 1–17.
Saji VS, Choe HC, Yeung KWK. Nanotechnology in biomedical applications : a review. Int J Nano Biomater. 2010;3(2):119–39.
Silva GA. Neuroscience nanotechnology: progress, opportunities and challenges. Nat Rev. 2006;7(1):65–74.
Sun S. Recent advances in chemical synthesis, self-assembly, and applications of FePt nanoparticles. Adv Mater. 2006;18:393–403.
Thimiri Govinda Raj DB, Khan NA. Designer nanoparticle : nanobiotechnology tool for cell biology. Nano Converg. 2016;3(22):1–12.
Wade DT, Halligan PW. Do biomedical models of illness make for good healthcare systems? Br Med J. 2004;329(7479):1398–401.
Wang EC, Wang A. Nanoparticles and their applications in cell and molecular biology. Integr Biol. 2004;6(1):9–26.
Wu C, Yang Y, Hsu Y, Wu T. Nanoparticle-induced intraperitoneal hyperthermia and targeted photoablation in treating ovarian cancer. Oncotarget. 2015;6(29):26861–75.
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Patel, M.P., Patel, J.K. (2021). Biomedical Applications of Nanoparticles. In: Patel, J.K., Pathak, Y.V. (eds) Emerging Technologies for Nanoparticle Manufacturing. Springer, Cham. https://doi.org/10.1007/978-3-030-50703-9_2
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DOI: https://doi.org/10.1007/978-3-030-50703-9_2
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